TITLE:
Bilateral involvement in patients with granulomatous mastitis: Surgical treatment and case report
AUTHORS:
P. Orsaria, F. De Sanctis, A. Esser, L. Dori, E. Bonanno, G. Petrella, O. Buonomo
KEYWORDS:
Granulomatous Mastitis; Medical Treatment; Breast Conserving Therapy; Surgical Margins
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.2 No.9,
December
13,
2013
ABSTRACT: Introduction:
Granulomatous mastitis (GM) is a rare benign histopathologic lesion, associated
with tissue inflammation, architectural distortions and heterogeneous
parenchymal inflammation upon radiological evaluation. The treatment of GM is
controversial, and currently, there is no consensus about the most appropriate
therapy. Case Presentation: We presented a unique, atypical GM case with a
prolonged disease course that ultimately led to a bilateral mastectomy. A
conservative therapeutic approach and limited or wide surgical excisions have
failed to prevent unfavorable outcomes in both the initial presentation and recurrent disease. Conclusions: There’re
no clear data in the literature delineating persistent recurrences of GM after
conservative treatment and multiple surgeries. Obtaining a disease-free
surgical margin might be an important prognostic factor for a lasting relapse-free
clinical resolution.