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Clatz, O., Sermesant, M., Bondiau, P., Delingette, H., Warfield, S., Malandain, G. and Ayache, N. (2005) Realistic simulation of the 3D growth of brain tumors in MR images coupling diffusion with biomechanical deformation. IEEE Transactions on Medical Imaging, 24, 1334-1346.

has been cited by the following article:

• TITLE: In Vivo Dynamic Image Characterization of Brain Tumor Growth Using Singular Value Decomposition and Eigenvalues

  AUTHORS: Murad Shibli

  KEYWORDS: Brain cancer, Tumor Image Identification, Singular Value Decomposition

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.4 No.3, March 8, 2011

  ABSTRACT: This paper presents a dynamic image approach to characterize the growth of brain cancer invasion of tumor gliomas cells using singular value decomposi-tion (SVD) technique. Such a dynamic image is identi-fied by the white and grey matter displayed by mag-netic resonance (MR) images of the patient brain taken at different times. SVD components and prop-erties have been analyzed for different brain images. It is figured out that the growth of tumor cells is quantized by the SVD eigenvalues. Since SVD geo-metrically interprets an ellipsoid transformation, then the higher the eigenvalues, the more of tumor growth is. In vivo SVD dynamic imaging offers a more pre-dictive model to assess the tumor therapy than con-ventional technologies. Furthermore, an efficient dy-namic white-black indicator of the tumor growth rate is constructed based on the change in the diagonal eigenvalues matrices of two MR images taken at dif-ferent times. Finally, SVD image processing results are demonstrated to verify the effectiveness of the applied approach that can be implemented for each individual patient.