TITLE:
Properties of Microcrystalline Chitosan-Calcium Phosphate Complex Composite
AUTHORS:
Luciano Pighinelli, Magdalena Kucharska
KEYWORDS:
Microcrystalline Chitosan; Calcium Phosphate; Functional Biopolymer; Medical Applications
JOURNAL NAME:
Journal of Biomaterials and Nanobiotechnology,
Vol.4 No.4A,
December
11,
2013
ABSTRACT: Nature itself uses materials like, cellulose to provide the structure of plants, chitin as the exoskeleton of several insects and molluscs, collagen for mechanical support in connective tissues and so on. At present, the socioeconomic situation of the modern world has raised the interest in renewable materials being used in regenerative medicine. The composition of MCCh/?-TCP complex in sponge shape is derived from the junction of two or more different materials, containing organic and inorganic materials, including bioactivity and biodegradability as a characteristic. The chemical characteristics of MCCh/?-TCP complex composites showed that both of the components organic and inorganic exist in the material. All sponge preparations, with MCCh/?-TCP have a well-shaped 3-dimentional structure, a highly porous and interconnected and homogenous pore structure to ensure a biological environment conducive to cell attachment and proliferation as well as tissue growth, providing the passage of nutrient flow. These materials can be used in future for medical applications as a base for scaffolds production and as implants in regenerative medicine.