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National Committee for Clinical Laboratory Standards, “Susceptibility Testing of Mycobacteria, Nocardia, and Other Aerobic Actinomycetes; Approved Standard,” 2nd Edition, CLSI Document M24-A2, Vol. 31, No. 5, 2011, pp. 3-19.

has been cited by the following article:

• TITLE: Synthesis and Evaluation of 2-Amino-4H-Pyran-3-Carbonitrile Derivatives as Antitubercular Agents

  AUTHORS: Chunxia Chen, Minghui Lu, Zhihui Liu, Junting Wan, Zhengchao Tu, Tianyu Zhang, Ming Yan

  KEYWORDS: 2-Amino-4H-Pyran-3-Carbonitrile; Synthesis; Antitubercular Activity

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.3 No.4, December 5, 2013

  ABSTRACT: A series of 2-amino-4H-pyran-3-carbonitrile derivatives were designed and synthesized. Their antitubercular activities were evaluated against autoluminescent M. tuberculosis H37Ra and standard strain M. tuberculosis H37Rv. No obvious antitubercular activities could be observed (MIC > 10 ug/mL). The results are in sharp contrast with the previously reported data.