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A. Goldbeter and D. E. Koshland, “An Amplified Sensitivity Arising from Covalent Modification in Biological Systems,” Proceedings of National Academy of Sciences of the United States of America, Vol. 78, No. 11, 1981, pp. 6840-6844. http://dx.doi.org/10.1073/pnas.78.11.6840

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