TITLE:
Rhino-Orbito-Cerebral Mucormycosis in a Diabetic Patient with Idiopathic CD4 + Lymphocytopenia
AUTHORS:
Nuno Rocha Pereira, Paulo Andrade, Laura Sá, Cândida Abreu, Rita Figueiredo, Roberto Silva, António Sarmento
KEYWORDS:
Mucormycosis; Idiopathic CD4 + Lymphocytopenia; Diabetes; Amphotericin B
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.3 No.4,
December
3,
2013
ABSTRACT: A 54-year-old diabetic male, with idiopathic CD4 + lymphocytopenia, was presented with a two-month history of headache and periocular pain followed by vertigo, left hypoacusia and left
peripheral facial palsy and hypoesthesia. More than a month after admission, a
palate ulcer appeared and Infectious Diseases consultation was required. Mucormycosis
was suspected and the diagnosis was confirmed by histologic examination.
Despite early surgery and combination antifungal therapy, the patient did not survive. This case report illustrates the difficulty in diagnosing a rare
condition with non-specific clinical manifestations and underlines the
importance of a timely multidisciplinary approach in order to recognise this
highly fatal disease earlier. It also
describes a previously non-reported situation of mucormycosis in a patient with
idiopathic CD4 + lymphocytopenia.