TITLE:
Synthesis, Characterization, Anti-Bacterial and Anti-Fungal Activities of New Quinoxaline 1,4-di-N-Oxide Derivatives
AUTHORS:
Dalia Hussein Soliman
KEYWORDS:
Quinoxaline 1, 4-di-N-Oxide; Beirut Reaction; Benzofuroxanes; β-Ketoamide; β-Cyanoamide; Antibacterial; Antifungal
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.3 No.3A,
November
28,
2013
ABSTRACT: A new series of quinoxaline 1,4-di-N-oxides were synthesized and evaluated for their antibacterial and antifungal activities. The best result was demonstrated by 3-amino-N-(4-methoxyphenyl)-2-quinoxalinecarboxamide 1,4-di-N-oxide 4e, MIC (0.24 μg/ml) against Aspergillus fumigatus, and (0.12 μg/ml) against Streptococcus pneumonia.