TITLE:
Post-transplant plasma cell hepatitis in a liver transplant patient treated with pegylated interferon plus ribavirin
AUTHORS:
Miguel Jiménez-Pérez, Francisco Javier Rando-Muñoz, Rocío González-Grande, Fernando González-Panizo Tamargo, Jesús de la Cruz Lombardo, Juan Miguel Rodrigo López, Román Manteca González
KEYWORDS:
Liver Transplantation; C Hepatitis Treatment; Plasmatic Cells; Allograft Rejection; Autoinmune Response
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.3 No.7,
November
26,
2013
ABSTRACT: The recurrence of hepatitis C after a liver
transplant remains an important cause of graft loss and retransplant. Antiviral
therapy with peginterferon plus ribavirin (PEG-INF/RBV) can achieve a sustained
viral response and histological improvement in a high percentage of cases.
However, this treatment is not exempt from important side effects or from the
possibility of precipitating rejection, with the resulting graft loss. We
report the case of a liver transplant patient who received treatment with
PEG-INF/RBV and developed plasma cell hepatitis as the presenting form of
rejection.