TITLE:
Effects of Ginkgo Biloba Special Extract EGb 761® in Very Mild Cognitive Impairment (vMCI)
AUTHORS:
Brigitte Grass-Kapanke, Arija Busmane, Andris Lasmanis, Robert Hoerr, Reiner Kaschel
KEYWORDS:
Ginkgo Biloba, EGb 761®, Mild Cognitive Impairment, Memory, Concentration, Randomised Controlled Trial
JOURNAL NAME:
Neuroscience and Medicine,
Vol.2 No.1,
March
17,
2011
ABSTRACT: Objective: To assess effects of EGb 761® on cognition and quality of life in subjects with very mild cognitive impair-ment. Methods: We randomized 300 subjects aged 45 to 65 with cognitive complaints and low functioning (more than one standard deviation below appropriate norm) in at least one cognitive test to double-blind treatment with once daily 240 mg EGb 761® or placebo for 12 weeks. Results: The exploratory intention-to-treat analysis showed significant im-provement (p