TITLE:
Diabetic mouse models
AUTHORS:
Yoshiaki Katsuda, Takeshi Ohta, Masami Shinohara, Tong Bin, Takahisa Yamada
KEYWORDS:
Diabetes; Diabetic Complication; Mouse Model; Obesity
JOURNAL NAME:
Open Journal of Animal Sciences,
Vol.3 No.4,
November
20,
2013
ABSTRACT: The number of patients with lifestyle-related diseases, such as cardiovascular disease, diabetes mellitus, hypertension, atherosclerosis, and cancer, is increasing all over the world, and that of diabetics is increasing especially rapidly. Diabetic animal models have played a key role in elucidating the etiology of diabetes and developing anti-diabetic drugs. In this review, we overviewed characteristics of diabetic mouse models and pharmacological evaluation using the diabetic models.