Advances in Bioscience and Biotechnology

Advances in Bioscience and Biotechnology

ISSN Print: 2156-8456
ISSN Online: 2156-8502
www.scirp.net/journal/abb
E-mail: [email protected]
"pHluorin2: an enhanced, ratiometric, pH-sensitive green florescent protein"
written by Matthew John Mahon,
published by Advances in Bioscience and Biotechnology, Vol.2 No.3, 2011
has been cited by the following article(s):
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[3] Progress in pH-Sensitive sensors: essential tools for organelle pH detection, spotlighting mitochondrion and diverse applications
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[4] GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
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[5] A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish
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[7] Dysregulation of intercellular communication in vitro and in vivo via extracellular vesicles secreted by pancreatic duct adenocarcinoma cells and generated under the …
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[8] Author Spotlight: Advancements in Glycosomal pH Monitoring in Trypanosoma brucei Using pHluorin2 Biosensor
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[10] Human iPSC genetically encoded fluorescent biosensor models for toxicity imaging
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[11] Measuring Dynamic Glycosomal pH Changes in Living Trypanosoma brucei
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[12] Potassium-mediated bacterial chemotactic response
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[13] Design of a two-fluorophore pH biosensor targeted to the digestive vacuole of Plasmodium falciparum
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[14] Burkholderia cenocepacia antimicrobial resistance and physiology at acidic pH in the cystic fibrosis nutritional environment
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[15] Intrinsically disordered proteins as physicochemical sensors
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[16] Cryo-printed microfluidics enable rapid prototyping for optical-cell analysis
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[17] The pH-dependent lactose metabolism of Lactobacillus delbrueckii subsp. bulgaricus: An integrative view through a mechanistic computational model
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[18] Viral attachment blocking chimera composed of DNA origami and nanobody inhibits Pseudorabies Virus infection in vitro
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[19] Quantifying pH in Malaria Using pHluorin and Flow Cytometry
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[20] Seeing neurodegeneration in a new light using genetically encoded fluorescent biosensors and iPSCs
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[21] Fusion proteins of organophosphorus hydrolase and pHluorin for a whole-cell biosensor for organophosphorus pesticide measurement
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[22] Mapping of subcellular local pH in the marine diatom Phaeodactylum tricornutum
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[23] Using A Protoplast Transformation System to Enable Functional Studies in Mangifera indica L.
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[24] DRAGON: Harnessing the power of DNA repair for accelerating genome evolution in Corynebacterium glutamicum
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[25] VmPma1 contributes to virulence via regulation of the acidification process during host infection in Valsa mali
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[26] Intracellular kynurenine promotes acetaldehyde accumulation, further inducing the apoptosis in soil beneficial fungi Trichoderma guizhouense NJAU4742 under acid …
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[27] Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps)
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[28] Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy
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[29] Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae
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[30] Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
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[31] Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
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[32] Probing the Internal pH and Permeability of a Carboxysome Shell
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[33] Bioluminescence Color-Tuning Firefly Luciferases: Engineering and Prospects for Real-Time Intracellular pH Imaging and Heavy Metal Biosensing
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[34] pH Distribution along Growing Fungal Hyphae at Microscale
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[35] Establishment of Corynebacterium glutamicum for the heterologous production of bacteriocins
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[36] Synthetic Biology: Bottom-Up Assembly of Molecular Systems
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[37] Genetically Encoded Ratiometric pH Sensors for the Measurement of Intra-and Extracellular pH and Internalization Rates
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[38] Intracellular pH Control by Membrane Transport in Mammalian Cells. Insights Into the Selective Advantages of Functional Redundancy
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[39] The bacteriocin Angicin interferes with bacterial membrane integrity through interaction with the mannose phosphotransferase system
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[40] Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process
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[41] Characterization of Amyloidβ-Neurexin interaction in Alzheimer's disease
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[42] Cellular stress characterisation in S. cerevisiae budding yeast using optical microscopy
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[43] Evidence of a Novel Sodium Hydrogen Exchanger With Sperm Specific Expression
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[44] Improved fluorescent Listeria spp. biosensors for analysis of antimicrobials by flow cytometry
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[45] Activation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cells
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[46] Maturing autophagosomes are transported towards the cell periphery
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[47] Comparable initial engagement of intracellular signaling pathways by parathyroid hormone receptor ligands teriparatide, abaloparatide, and long‐acting PTH
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[48] Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH
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[49] Low-level brain somatic mutations are implicated in schizophrenia
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[50] Acidosis-induced activation of anion channel SLAH3 in the flooding-related stress response of Arabidopsis
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[51] Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligands
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[52] Illuminate the hidden: in vivo mapping of microscale pH in the mycosphere using a novel whole-cell biosensor
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[53] Absence of carbonic anhydrase in chloroplasts affects C3 plant development but not photosynthesis
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[54] Fluorescence lifetime imaging of pH along the secretory pathway
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[55] Visualization of integrin molecules by fluorescence imaging and techniques
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[56] Direct inhibitory effect on viral entry of influenza A and SARS‐CoV‐2 viruses by azithromycin
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[57] Growth response and recovery of Corynebacterium glutamicum colonies on single-cell level upon defined pH stress pulses
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[58] Human neurons from Christianson syndrome iPSCs reveal mutation-specific responses to rescue strategies
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[59] Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells
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[60] Salt Inducible Kinase activation and IRE1-dependent intracellular ATP depletion to form Sec bodies in Drosophila cells
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[61] CamelliA-based simultaneous imaging of Ca2+ dynamics in subcellular compartments
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[62] Fluorescent toys 'n'tools lighting the way in fungal research
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[63] Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
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[64] Discovery of putative prognostic and therapeutic miRNA in uEVs of Dent's Disease 1 patients and characterisation of cellular models of the disease
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[65] Genetically encoded fluorescent biosensors for detection of ligands and protein-protein interactions
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[66] Investigating the use of novel fluorescent nanosensors to measure chemical changes in bacterial surroundings
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[67] Formation of Cytoplasmic Actin-Cofilin Rods is Triggered by Metabolic Stress and Changes in Cellular pH
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[68] Activation of salt Inducible Kinases, IRE1 and PERK leads to Sec bodies formation in Drosophila S2 cells
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[69] TC10 regulates breast cancer invasion and metastasis by controlling membrane type-1 matrix metalloproteinase at invadopodia
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[70] Spatiotemporal Quantification of Cytosolic pH in Arabidopsis Pollen Tubes
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[71] Fluorescence-based sensing of the bioenergetic and physicochemical status of the cell
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[72] Leucine-Responsive Regulatory Protein in Acetic Acid Bacteria Is Stable and Functions at a Wide Range of Intracellular pH Levels
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[73] Investigating the loss of sodium/proton exchanger isoform 6 (nhe6) function in christianson syndrome
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[74] Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants
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[75] Comparable initial engagement of intracellular signaling pathways by parathyroid hormone receptor ligands teriparatide, abaloparatide, and long acting PTH
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[76] Triclosan Disrupts Immune Cell Function by Depressing Ca2+ Influx via Acidification of the Cytoplasm
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[77] in basic and clinical sciences
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[78] A new pH sensor localized in the Golgi apparatus of Saccharomyces cerevisiae reveals unexpected roles of Vph1p and Stv1p isoforms
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[79] Acidification of Cytoplasm in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance
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[80] Acidification of Cytoplasmic pH in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance
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[81] An acid-tolerance response system protecting exponentially growing Escherichia coli
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[82] A survey of biological building blocks for synthetic molecular communication systems
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[83] A putative bet-hedging strategy buffers budding yeast against environmental instability
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[84] A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast
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[85] Cancer and pH dynamics: Transcriptional regulation, proteostasis, and the need for new molecular tools
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[86] Bacterial vivisection: how fluorescence-based imaging techniques shed a light on the inner workings of bacteria
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[87] DNA-Origami-Based Fluorescence Brightness Standards for Convenient and Fast Protein Counting in Live Cells
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[88] Metabolic diversification as a buffer against environmental instability in budding yeast
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[89] Illuminating Bacterial Electrophysiology
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[90] Bet hedging buffers budding yeast against environmental instability
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[91] Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae
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[92] Subcompartment Formation by Phase Separation
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[93] Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome
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[94] Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes
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[95] Reversible and irreversible fluorescence activity of the Enhanced Green Fluorescent Protein in pH: Insights for the development of pH-biosensors
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[96] The SensorOverlord predicts the accuracy of measurements with ratiometric biosensors
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[97] Synaptic Organizers in Alzheimer's Disease: a classification based on amyloid-β sensitivity
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[98] Interrogating Cellular Communication in Cancer with Genetically Encoded Imaging Reporters
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[99] Genetically Encoded Tools for Research of Cell Signaling and Metabolism under Brain Hypoxia
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[100] Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
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[101] AAV diffuses across zona pellucida for effortless gene delivery to fertilized eggs
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[102] Improved GPCR ligands from nanobody tethering
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[103] THE ROLE OF CHLOROPLAST CARBONIC ANHYDRASES IN THE DEVELOPMENT OF C3 PHOTOSYNTHESIZING PLANTS
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[104] Bioinformatic Analysis and Design of a GLUT3 Construct to Examine Cell Surface Expression
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[105] An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in …
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[106] Non‐invasive, ratiometric determination of intracellular pH in Pseudomonas species using a novel genetically encoded indicator
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[107] Automated high-throughput high-content autophagy and mitophagy analysis platform
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[108] Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions
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[109] pH Nanosensor Using Electronic Spins in Diamond
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[110] Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements
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[112] Live cell imaging of signaling and metabolic activities
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[113] Analysis of Golgi pH in Chinese hamster ovary cells using ratiometric pH‐sensitive fluorescent proteins
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[114] On the development of optical peripheral nerve interfaces
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[115] INSIGHTS TO CHROMOPHORE INTERACTIONS IN GREEN FLUORESCENT PROTEIN AND ITS VARIANTS
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[116] Novel application of Macrolampis sp2 firefly luciferase for intracellular pH-biosensing in mammalian cells
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[118] 基于慢病毒系统的双荧光标记多功能自噬流监测系统建立与应用 *
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[119] Investigating the Role of LIMK1 Signaling in PKA-dependent LTP in the Hippocampus
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[120] Divergent Single-Cell Trajectories in Homeostatic Control and Genome Instability during Aging
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[121] A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome
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[122] Perspective Tools for Optogenetics and Photopharmacology: From Design to Implementation
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[123] Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks
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[124] Intracellular pHluorin as sensor for easy assessment of bacteriocin-induced membrane-damage in Listeria monocytogenes
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[125] A recurrent missense variant in SLC9A7 causes nonsyndromic X-linked intellectual disability with alteration of Golgi acidification and aberrant glycosylation
Human Molecular Genetics, 2018
[126] Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells
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[127] Genetically encoded fluorescent indicators for live cell pH imaging
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018
[128] Mechanisms Underlying Biphasic Synaptic Vesicle Acidification in Glutamatergic Synapses
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[129] Biobased, Internally pH-Sensitive Materials: Immobilized Yellow Fluorescent Protein as an Optical Sensor for Spatiotemporal Mapping of pH Inside Porous Matrices
ACS Applied Materials & Interfaces, 2018
[130] Environmental Decontamination of a Chemical Warfare Simulant Utilizing a Membrane Vesicle-Encapsulated Phosphotriesterase
ACS Applied Materials & Interfaces, 2018
[131] Novel Methods for Monitoring Glucose Metabolism in Trypanosoma brucei Using Fluorescent Biosensors
ProQuest Dissertations Publishing, 2018
[132] A novel CLCN5 pathogenic mutation supports Dent disease with normal endosomal acidification
Human mutation, 2018
[133] Redox biosensors in a context of multiparameter imaging
Free Radical Biology and Medicine, 2018
[134] Imaging of electrical activity in small diameter fibers of the murine peripheral nerve with virally-delivered GCaMP6f
Scientific Reports, 2018
[135] To appear in: Free Radical Biology and Medicine
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[136] Phase separation of a yeast prion protein promotes cellular fitness
2018
[137] Conditional toxicity and synergy drive diversity among antibacterial effectors
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[138] Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery
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[139] Synthesis and properties of the para-trimethylammonium analogues of green fluorescence protein (GFP) chromophore: The mimic of protonated GFP chromophore
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[140] Population heterogeneity in microbial bioprocesses: origin, analysis, mechanisms, and future perspectives
Bioprocess and Biosystems Engineering, 2018
[141] imaging, Free Radical Biology and Medicine
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[142] On the role of CIC-5 anion/proton exchangers in endocytosis: insights from intestinal infections and the hereditary renal dent's disease
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[143] Exploration of Non-Viral Gene Delivery Methods for Safe and Efficient Protein Expression in Non-Dividing Mammalian Cell Types
2018
[144] Illuminating pathogen–host intimacy through optogenetics
2018
[145] In Pursuit of an Optical Peripheral Nerve Interface: Targeting Axons and Evaluation of a Genetically Encoded Indicator
2017
[146] The Rap GTPases coordinate actin and microtubule cytoskeleton reorganization, and promote antigen extraction at the B cell immune synapse
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[147] Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator
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[148] Rôle du jeûne et de la perturbation de la cascade de signalisation de l'insuline sur le clivage du précurseur de la protéine amyloïde (APP)
2017
[149] Dynamics and Liquid-Like Behavior of the Pyrenoid of the Green Alga Chlamydomonas reinhardtii
2017
[150] Recent Advances in Development of Genetically Encoded Fluorescent Sensors
Methods in Enzymology, 2017
[151] Imaging of Intracellular pH in Tumor Spheroids Using Genetically Encoded Sensor SypHer2
Multi-Parametric Live Cell Microscopy of 3D Tissue Models, 2017
[152] Live Cell Imaging Reveals pH Oscillations in Saccharomyces cerevisiae During Metabolic Transitions
Scientific Reports, 2017
[153] Development and application of a recombination-based library versus library high-throughput yeast two-hybrid (RLL-Y2H) screening system
Nucleic Acids Research, 2017
[154] Live-cell Microscopy and Fluorescence-based Measurement of Luminal pH in Intracellular Organelles
Frontiers in Cell and Developmental Biology, 2017
[155] SRpHi ratiometric pH biosensors for super-resolution microscopy
Nature Communications, 2017
[156] Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm.
eLife, 2017
[157] Mechanically switching single-molecule fluorescence of GFP by unfolding and refolding
2017
[158] Characterization of a Missense Mutation in the Alkali Cation/Proton Exchanger SLC9A7 that Associates with a Novel Form of X-linked Intellectual Disability
2017
[159] Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm
2017
[160] Optical Quantification of Intracellular pH in
Journal of Visualized Experiments, 2017
[161] Nanotechnology and Neuroscience Convergence: A Novel Tool for Neurotransmitters Monitoring
2017
[162] Determination of glucose deficiency-induced cell death by mitochondrial ATP generation-driven proton homeostasis
Journal of Molecular Cell Biology, 2017
[163] In Vivo Indicators of Cytoplasmic, Vacuolar, and Extracellular pH Using pHluorin2 in Candida albicans
2017
[164] Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking
2017
[165] Vacuolar ATPase in phago (lyso) some biology
International Journal of Medical Microbiology, 2017
[166] Ammonium chloride alters neuronal excitability and synaptic vesicle release
Scientific Reports, 2017
[167] pHluorins–a tool to measure intracellular pH
2016
[168] Recent developments of genetically encoded optical sensors for cell biology
Biology of the Cell, 2016
[169] How does neuroprotective sAPPα initiate its signalling cascade?
2016
[170] Live-cell imaging approaches for the investigation of xenobiotic-induced oxidant stress
Biochimica et Biophysica Acta (BBA) - General Subjects, 2016
[171] Cellular models for Parkinson's disease
Journal of neurochemistry, 2016
[172] pH‐sensitive pHluorins as a molecular sensor for in situ monitoring of enzyme‐catalyzed prodrug activation
Biotechnology and applied biochemistry, 2016
[173] A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy
2016
[174] Design and development of genetically encoded fluorescent sensors to monitor intracellular chemical and physical parameters
Biophysical Reviews, 2016
[175] Fluorescence-based ion concentration measurements in living cells and tissues
2016
[176] Molecular and cellular insights into mitochondrial contributions to neuronal autophagy: links to energetics and mitophagy
2016
[177] Life Under the Microscope: Quantifying Live Cell Interactions to Improve Nanoscale Drug Delivery
ACS Sensors, 2016
[178] Peroxide dependent effects in human airway epithelial cells exposed to oxidant air pollutants
ProQuest Dissertations Publishing, 2016
[179] Maintaining proton homeostasis is an essential role of glucose metabolism in cell survival
2016
[180] REVIEW Cellular models for Parkinson's disease
2016
[181] Improved Methods for the Development and Adaptation of Protein Switches
2015
[182] RECONNOITERING WNTLESS IN THE WNT SECRETION PATHWAY
2015
[183] Engineering of red fluorescent proteins and red fluorescent protein-based pH biosensors
2015
[184] pH 敏感型荧光蛋白及其在植物细胞生物学中的应用
植物学报, 2015
[185] Fluorescent protein biosensors applied to microphysiological systems
Experimental Biology and Medicine, 2015
[186] Mutations associated with Dent's disease affect gating and voltage dependence of the human anion/proton exchanger ClC-5
Frontiers in Physiology, 2015
[187] Fluorescent ratiometric pH indicator SypHer2: Applications in neuroscience and regenerative biology
Biochimica et Biophysica Acta (BBA)-General Subjects, 2015
[188] 14-3-3 Proteins Buffer Intracellular Calcium Sensing Receptors to Constrain Signaling
PloS one, 2015
[189] pH-sensitive fluorescent proteins and their applications in plant cell biology
Chinese Bulletin of Botany, 2015
[190] Photochemical & Photobiological Sciences
Photochem. Photobiol. Sci, 2014
[191] Understanding the Structural Basis for Transmembrane Signaling in the CLR-RAMP1 Heterodimer
2014
[192] Novel application of pH-sensitive firefly luciferases as dual reporter genes for simultaneous ratiometric analysis of intracellular pH and gene expression/location
Photochemical & Photobiological Sciences, 2014
[193] Application of BRET for studying G protein-coupled receptors
Mini reviews in medicinal chemistry, 2014
[194] A genetically-encoded YFP sensor with enhanced chloride sensitivity, photostability and reduced ph interference demonstrates augmented transmembrane …
PLOS ONE, 2014
[195] Intracellular pH responses in the industrially important fungus< i> Trichoderma reesei
Fungal Genetics and Biology, 2014
[196] The zebrafish merovingian mutant reveals a role for pH regulation in hair cell toxicity and function
Disease models & mechanisms, 2014
[197] A Genetically-Encoded YFP Sensor with Enhanced Chloride Sensitivity, Photostability and Reduced pH Interference Demonstrates Augmented Transmembrane Chloride Movement by Gerbil Prestin (SLC26a5)
PloS one, 2014
[198] Intracellular pH responses in the industrially important fungus Trichoderma reesei
Fungal Genetics and Biology, 2014
[199] Understanding the Structural Basis for Transmembrane Signaling inthe CLR-RAMP1 Heterodimer
2014
[200] FLUORESCENT CHEMOSENSORS FOR THE DETECTION OF BIOLOGICAL AMINES
Dissertation, 2014
[201] A genetically-encoded YFP sensor with enhanced chloride sensitivity, photostability and reduced ph interference demonstrates augmented transmembrane …
2014
[202] SNARE proteins in human mast cells
2013
[203] Non-invasive High-Throughput Single-Cell Analysis of the Intracellular pH of Yeast by Ratiometric Flow Cytometry
2013
[204] Development and properties of genetically encoded pH sensors in plants
Frontiers in plant science, 2013
[205] Illumination of the Spatial Order of Intracellular pH by Genetically Encoded pH-Sensitive Sensors
Sensors, 2013
[206] Noninvasive high-throughput single-cell analysis of the intracellular pH of saccharomyces cerevisiae by ratiometric flow cytometry
Applied and environmental microbiology, 2013
[207] Development and Validation of a Novel Quantitative Assay for Cell surface Expression of GPCRs using a Receptor β-lactamase fusion Protein and the Colourometric …
2013
[208] Noninvasive High-Throughput Single-Cell
2013
[209] Development and Validation of a Novel Quantitative Assay for Cell Surface expression of GPCRs using a Receptor beta-lactamase Fusion Protein and the …
2013
[210] Saccharomyces cerevisiae — a model to uncover molecular mechanisms for yeast biofilm biology
Pathogens and Disease, 2012
[211] Inhibitors of V-ATPase proton transport reveal uncoupling functions of tether linking cytosolic and membrane domains of V0 subunit a (Vph1p)
Journal of Biological Chemistry, 2012
[212] Saccharomyces cerevisiae–a model to uncover molecular mechanisms for yeast biofilm biology
FEMS Immunology & Medical Microbiology, 2012
[213] In vivo determination of organellar pH using a universal wavelength-based confocal microscopy approach
PloS one, 2012
[214] The flatworm Macrostomum lignano is a powerful model organism for ion channel and stem cell research
Stem cells international, 2012
[215] Saccharomyces cerevisiae—a model to uncover molecular mechanisms for yeast biofilm biology
2012
[216] Characterisation of two calmodulin-related calcium sensors, CaBP7 and CaBP8
Thesis, 2011
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