Prof. Sabzali A. Javadov

School of Medicine

University of Puerto Rico, USA

Associate Professor

Email: [email protected]

Qualifications

1992 D.Sc., Cardiology Research Center, Russian Academy of Medical Sciences, and Moscow State University, Cardiac Pathophysiology & Biochemistry

1986 Ph.D., Cardiology Research Center, Russian Academy of Medical Sciences, Cardiology & Biochemistry

1983 M.D., Russian Medical University, Medical Biochemistry

Publications (Selected)

1. Kozlov, A. V., Javadov, S., & Sommer, N. (2024). Cellular ROS and antioxidants: physiological and pathological role. Antioxidants, 13(5), 602.
2. Chapa-Dubocq, X. R., Rodríguez-Graciani, K. M., García-Báez, J., Vadovsky, A., Bazil, J. N., & Javadov, S. (2023). The role of swelling in the regulation of OPA1-mediated mitochondrial function in the heart in vitro. Cells, 12(16), 2017.
3. Chapa-Dubocq, X. R., Rodríguez-Graciani, K. M., García-Báez, J., Vadovsky, A., Bazil, J. N., & Javadov, S. (2023). The role of swelling in the regulation of OPA1-mediated mitochondrial function in the heart in vitro. Cells, 12(16), 2017.
4. Jang, S., Chorna, N., Rodríguez-Graciani, K. M., Inyushin, M., Fossati, S., & Javadov, S. (2023). The effects of amyloid-β on metabolomic profiles of cardiomyocytes and coronary endothelial cells. Journal of Alzheimer’s Disease, 93(1), 307-319.
5. Chapa-Dubocq, X. R., Garcia-Baez, J. F., Bazil, J. N., & Javadov, S. (2023). Crosstalk between adenine nucleotide transporter and mitochondrial swelling: Experimental and computational approaches. Cell biology and toxicology, 39(2), 435-450.
6. Kuznetsov, A. V., Javadov, S., Margreiter, R., Hagenbuchner, J., & Ausserlechner, M. J. (2022). Analysis of mitochondrial function, structure, and intracellular organization in situ in cardiomyocytes and skeletal muscles. International Journal of Molecular Sciences, 23(4), 2252.
7. Rodríguez-Graciani, K. M., Chapa-Dubocq, X. R., Ayala-Arroyo, E. J., Chaves-Negrón, I., Jang, S., Chorna, N., ... & Javadov, S. (2022). Effects of ferroptosis on the metabolome in cardiac cells: the role of glutaminolysis. Antioxidants, 11(2), 278.
8. Jang, S., Chapa-Dubocq, X. R., Parodi-Rullán, R. M., Fossati, S., & Javadov, S. (2022). Beta-amyloid instigates dysfunction of mitochondria in cardiac cells. Cells, 11(3), 373.
9. Jang, S., Chapa-Dubocq, X. R., Fossati, S., & Javadov, S. (2021). Analysis of mitochondrial calcium retention capacity in cultured cells: Permeabilized cells versus isolated mitochondria. Frontiers in physiology, 12, 773839.
10. Jang, S., Chapa-Dubocq, X. R., Tyurina, Y. Y., St Croix, C. M., Kapralov, A. A., Tyurin, V. A., ... & Javadov, S. (2021). Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes. Redox Biology, 45, 102021.
11. Sparvero, L. J., Tian, H., Amoscato, A. A., Sun, W. Y., Anthonymuthu, T. S., Tyurina, Y. Y., ... & Bayır, H. (2021). Direct mapping of phospholipid ferroptotic death signals in cells and tissues by gas cluster ion beam secondary ion mass spectrometry (GCIB‐SIMS). Angewandte Chemie, 133(21), 11890-11894.
12. Kuznetsov, A. V., Javadov, S., Margreiter, R., Grimm, M., Hagenbuchner, J., & Ausserlechner, M. J. (2021). Structural and functional remodeling of mitochondria as an adaptive response to energy deprivation. Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1862(6), 148393.
13. Chapa-Dubocq, X. R., Rodríguez-Graciani, K. M., Guzmán-Hernández, R. A., Jang, S., Brookes, P. S., & Javadov, S. (2020). Cardiac function is not susceptible to moderate disassembly of mitochondrial respiratory supercomplexes. International journal of molecular sciences, 21(5), 1555.
14. Jang, S., & Javadov, S. (2020). OPA1 regulates respiratory supercomplexes assembly: The role of mitochondrial swelling. Mitochondrion, 51, 30-39.
15. Makarov, V. I., Khmelinskii, I., Khuchua, Z., & Javadov, S. (2020). In silico simulation of reversible and irreversible swelling of mitochondria: The role of membrane rigidity. Mitochondrion, 50, 71-81.
16. M. Parodi-Rullán, R., Chapa-Dubocq, X., Guzmán-Hernández, R., Jang, S., A. Torres-Ramos, C., Ayala-Peña, S., & Javadov, S. (2019). The role of adenine nucleotide translocase in the assembly of respiratory supercomplexes in cardiac cells. Cells, 8(10), 1247.

Profile Details

WoS ResearcherID: J-9594-2017

https://www.researchgate.net/profile/Sabzali-Javadov