Dr. Nobuhiko Miyazawa

Dementia center, Fuefuki Central Hospital

Japan

E-mail: [email protected]

Qualifications

2022 Director, Dementia center, Fuefuki central Hospital.

2004 Director, PET center, Kofu Neurosurgical Hospital, Japan

1998 Assistant Professor, Department of Neurosurgery, Yamanashi University, Japan

1989 Research Fellow, Division of Neuro-isotope, Montreal Neurological Institute, Canada

Publications (selected)

1. Miyazawa N, Yamazaki H, Wakao T, et al. Epidermoid tumors of Meckel’s cave: case report and review of the literature. Neurosurgery. 1989; 25: 951-955.
2. Miyazawa N, Diksic M, Yamamoto Y. Chronological study of peripheral benzodiazepine biding sites in rat brain stab wounds using [3H] PK-11195 as a maker for gliosis. Acta Neurochir (Wien). 1995; 137: 207-216.
3. Miyazawa N, Fukamachi A, Nukui H. Evaluation of regional cerebral blood flow in high-intensity foci in white matter on T2-weighted magnetic resonance imaging using stable Xenon CT. Acta Neurol Scand. 1996;166:162.
4. Miyazawa N, Mitsuka S, Nukui H. Xenon CT CBF study in patients with brain stem infarction. Cerebrovasc Dis. 1996; 6: 86.
5. Miyazawa N, Satoh T, Hashizume K, et al. Xenon contrast CT-CBF measurements in high-intensity foci on T2-weighted MR images in Centrum Semiovale of asymptomatic individuals. Stroke. 1997; 28: 984-987.
6. Miyazawa N, Nukui H, Mitsuka S, et al. Surgical treatment of serious cases of ruptured cerebral aneurysm. Clin Neurol Neurosurg. 1997; 99: 46.
7. Miyazawa N, Hamel E, Diksic M. Assessment of the peripheral benzodiazepine receptors in human gliomas by two methods. J Neuro-Oncol. 1998; 38: 19-26.
8. Miyazawa N, Mitsuka S, Asahara T, et al. Clinical features of relative focal hyperperfusion in patients with intracerebral hemorrhage detected by contrast-enhanced Xenon CT. AJNR Am J Neuroradiol. 1998; 19: 1741-1746.
9. Miyazawa N, Koizumi K, Mitsuka S, et al. Discrepancies in brain perfusion SPECT findings between Tc-99m HMPAO and Tc-99m ECD: evaluation using dynamic SPECT in patients with hyperemia. Clin Nucl Med. 1998; 23: 686-690.
10. Miyazawa N, Koizumi K, Arbab AS, et al. Dynamic 99mTc-ECD SPET correlates well with 201Tl indices in brain tumours. Nucl Med Comm. 1999; 20: 1023-1029.
11. Miyazawa N, Nukui H, Mitsuka S, et al. Treatment of intradural paraclinoidal aneurysms. Neurol Med Chir. 1999; 39: 727-734.
12. Miyazawa N, Uchida M, Fukamachi A, et al. Xenon contrast-enhanced CT imaging of supratentorial hypoperfusion in patients with brain stem infarction. AJNR Am J Neuroradiol. 1999; 20: 1858-1862.
13. Miyazawa N, Fukui A, Fukamachi A, et al. Clinical features of patients with multiple occlusion or/and multiple stenosis of major cerebral artery. J Stroke Cerebrovasc Dis. 2000; 1: 137-138.
14. Miyazawa N, Saji H, Takaishi Y, et al. Protective effect of FK506 in the reperfusion model after short-term occlusion of middle cerebral artery in the rat: assessment by autoradiography using [125I] PK-11195. Neurol Res. 2000; 22: 630-633.
15. Miyazawa N, Nukui H, Yagi S, et al. Statistical analysis of factors affecting the outcome of patients with ruptured distal anterior cerebral artery aneurysms. Acta Neurochir(Wien). 2000; 142: 1241-1246.
16. Miyazawa N, Hida K, Iwasaki Y, et al. MRI at 1.5 T of intramedullary ependymoma and classification of pattern of contrast enhancement. Neuroradiology. 2000; 42: 828-832.
17. Miyazawa N, Hashizume K, Uchida M, et al. Long-term follow-up of asymptomatic patients with major artery occlusion: rate of symptomatic change and evaluation of cerebral hemodynamics. AJNR Am J Neuroradiol. 2001; 22: 243-247.
18. Miyazawa N, Toyama K, Arbab AS, et al. Evaluation of crossed cerebellar diaschisis in 30 patients major cerebral artery occlusion by means of quantitative I-123 IMP SPECT. Ann Nucl Med. 2001; 15: 513-519.
19. Miyazawa N, Nukui H, Horikoshi T, et al. Surgical management of aneurysms of the bifurcation of the internal carotid artery. Clin Neurol Neurosurg. 2002; 104: 103-114.
20. Miyazawa N, Aoki S, Toyama K, et al. Velocity-coded colour maganetic resonance angiography and perfusion-weighted magnetic resonance imaging for the evaluation of extracranial-to-intracranial artery bypass surgery. Clin Neurol Neurosurg. 2002; 105: 48-59.
21. Miyazawa N, Hayashi M, Komiya K, et al. Supernumenary phantom limbs associated with left hemispheric stroke: case report and review of the literature. Neurosurgery. 2004; 54: 228-231.
22. Miyazawa N, Arbab AS, Umeda T, et al. Perfusion CT investigation of chronic internal carotid artery occlusion: comparison with SPECT. Clin Neurol Neurosurg. 2005; 108: 11-17.
23. Miyazawa N, Akiyama I, Yamagata Z. Risk factors for growth of unruptured intracranial aneurysms: follow-up study by serial 0.5-T magnetic resonance angiography. Neurosurgery. 2006; 58: 1047-1053.
24. Miyazawa N, Akiyama I. Diffuse idiopathic skeletal hyperostosis associated with risk factors for stroke: a case-control study. Spine. 2006; 31: 225-229.
25. Miyazawa N, Akiyama I, Yamagata Z. Risk factors for the association of intracranial and aortic aneurysms. Acta Neurochir(Wien). 2007; 149: 221-229.
26. Miyazawa N, Akiyama I. Ossification of the ligamentum flavum of the cervical spine. J Neurosurg Sci. 2007; 51: 139-144.
27. Miyazawa N, Akiyama I, Yamagata Z. Analysis of incidence and risk factors for progression in patients with intracranial steno-occlusive lesions by serial magnetic resonance angiography. Clin Neurol Neurosurg. 2007; 109: 680-685.
28. Miyazawa N, Ishigame K, Kato S, et al. Thoracic chordoma: review and role of FDG-PET. J Neurosurg Sci. 2008; 52: 117-122.
29. Miyazawa N, Shinohara T, Nagasaka T, et al. Hypermetabolism in patients with dementia with Lewy bodies. Clin Nucl Med. 2010; 35: 490-493.
30. Miyazawa N, Shinohara T, Yamagata Z. Association of incompleteness of the anterior part of the circle of Willis with the occurrence of lacunes in the basal ganglia. Eur J Neurol. 2011; 18: 1358-1360.
31. Miyazawa N, Shinohara T. [18F] fluoro-deoxyglucose positron emission tomography in Alzheimer’s disease and related disorders. In: Hsieh CH, Ed. Positron Emission Tomography: Current Clinical and Research Aspects, Rijeka, Croatia: InTech, 2012:pp225-254.
32. Miyazawa N. Correlation between changes of FDG-PET findings and those of Mini-Mental Status Examination scores in patients with moderate Alzheimer’s disease: usefulness of stereotactic extraction estimation. Curr Mol Imag. 2014; 3: 10-14.
33. Miyazawa N, Shinohara T. FDG-PET studies of Semantic Dementia; a review. Curr Mol Imag. 2015; 4:126-130.
34. Miyazawa N. Creutzfelt-Jakob disease mimicking Alzheimer disease and dementia with Lewy Bodies-findings of FDG-PET with 3-dimentional stereotactic surface projection. Clin Nucl Med. 2017: 42; 247-248.
35. Miyazawa N, Shinohara T. Cerebral blood flow-single-photon emission computed tomography and Brodmann mapping may facilitate the evaluation of clinical features of early-onset Alzheimer’s disease. Front Clin Neurol Neurosurg, 2022: 1; 101--104.
36. Miyazawa N, Shinohara T. Single photon computed tomography (SPECT) findings in cases with adult-attention-deficit/hyperactivity disorder (ADHD): special attention to cerebellar posterior lobe hypoperfusion on Iodoamphetamine (IMP) SPECT using 3 dimensional stereotactic surface projection (3D-SSP) analysis. Open access J Neurol & Neurosurg, DOI; 10.19080/OAJNN 2023.18.555991.
37. Fukamachi A, Yagishita T, Miyazawa N, Sasaki H, Nukui H. Venous cerebral infarctions in an infant with subdural hematoma. Child’s Nerv Syst. 187; 3: 53-54.
38. Kaneko M, Fukamachi A, Sasaki H, Miyazawa N, Yagishita T, Nukui H. Intraoperative monitoring of the motor function; experimental and clinical study. Acta Neurochir suppl. 1988; 42: 18-21.
39. Nukui H, Kaneko M, Mitsuka S, Nishigaya K, Miyazawa N, Horikoshi T. Early operation in cases with ruptures basilar aneurysms. Intracranial aneurysms and arteriovenous malformation. Sugita K, Shibuya M ed. Nagoya University Coop. 1990; pp 55-59.
40. Yagishita T, Nukui H, Kanako M, Mitsuka S, Nishigaya K, Horikoshi T, Miyazawa N. Effect of continuous cisternal daranage for symptomatic vasospasm. Cerebral vasospasm. 1990; pp 311-313.
41. Nukui H, Mitsuka S, Hosaka T, Kakizawa T, Horikoshi T, Miyazawa N, Yagishita T. Fukamachi A, Shimizu T. Technical points to improve surgical results in cases with basilar tip aneurysms. Neuro Med Chir suppl 1998; 38: 74-78.
42. Arbab AS, Aoki S, Toyama K, Miyazawa N, Kumagai H, Umeda T, Arai T, Araki T, Arai T, Kabasawa H, Takahashi Y. Quantitative measurement of regional cerebral blood flow with flow-sensitive alternating invesuion recovery imaging; comparison with [Iodine 123]-Iodoamphetamine single photon emission CT. AJNR Am J Neuroradiol 2002;23:381-388.
43. Arbab AS, Aoki S, Toyama K, Araki T, Miyazawa N, Kumagai H, Umeda T, Arai T, Okubo T, Kabasawa H, Takahashi Y. Olin ptimal inversion time for acquiring flow-sensitive alternating inversion recovery images to quantify regional cerebral blood flow. Eur radiol. 2002; 12: 2950-2956.
44. Tsukahara S, Miyazawa N, Akagawa H, Forejtova S, Pavelka K, Tanaka T, Toh S, Tajima A, Akiyama I, Inoue I. COL6A1, the candidate gene for ossification of the posterior longitudinal ligament, is associated with diffuse idiopathic skeletal hypaerostosis in Japanese. Spine 2005; 30: 2321-2324.
45. Nagasaka T, Nagasaka K, Ohta E, Shindo K, Takiyama T, Shiozawa Z, Miyazawa N, Yamasaki N, Mori N, Onda H, Shinohara T. Cerebral hypermetabolism demonstrated by FDG PET in familial Creutzfeldt-Jakob Disease. Clin Nucl Med. 2011; 36: 725-727.
46. Ikeuchi T, Yano Y, Sato W, Morikawa F, Toru S, Nishimura C, Miyazawa N, Kuroha Y, Koike R, Tanaka S, Utsumi K, Kasuga K, Tokutake T, Ono K, Yano S, Naruse S, Yajima R, Hamano T, Yokoyama Y, Kitamura A, Kaneko E, Yamakado M, Nagao K. Development of a novel nutrition-related multivariate biomarker for mild cognitive impairment based on plasma free amino acid profile. Nutrients. 2022; 14: 637-652.

Last Updated: 2024-11-19