Prof. Ayman I. Sayegh

College of Veterinary Medicine

Tuskegee University, USA

Professor and Interim Head

Email: [email protected]

Qualifications

2000 Ph.D., Washington State University, USA, Neuroscience

1997 Surgical Internship, University of Illinois, USA, Equine Medicine and Surgery

1993 M.Sc., Kansas State University, USA, Equine Surgery

1987 D.V.M., Baghdad University, Iraq, Veterinary Medicine

Publications (selected)

1. Mhalhal, T. R., Washington, M. C., Heath, J. C., & Sayegh, A. I. (2021). Effect of vagotomy and sympathectomy on the feeding responses evoked by intra-aortic cholecystokinin-8 in adult male sprague dawley rats. Endocrine Research, 46(2), 57-65.
2. Dafalla, A. I., Mhalhal, T. R., Hiscocks, K., Heath, J., & Sayegh, A. I. (2020). The Vagus Nerve and the Celiaco-mesenteric Ganglia Participate in the Feeding Responses Evoked by Non-sulfated Cholecystokinin-8 in Male Sprague Dawley Rats. Endocrine Research, 45(2), 73-83.
3. Al-Sayegh, M., Ali, H., Jamal, M. H., ElGindi, M., Chanyong, T., Al-Awadi, K., & Abu-Farha, M. (2021). Mouse embryonic fibroblast adipogenic potential: A comprehensive transcriptome analysis. Adipocyte, 10(1), 1-20.
4. Dafalla, A. I., Mhalhal, T. R., Hiscocks, K., Heath, J., & Sayegh, A. I. (2019). Non-sulfated cholecystokinin-8 increases enteric and hindbrain Fos-like immunoreactivity in male Sprague Dawley rats. Brain research, 1708, 200-206.
5. Dafalla, A. I., Mhalhal, T. R., Washington, M. C., Spann, S., Reguero, A. M., Morgan, A. L., ... & Sayegh, A. I. (2019). Non-sulfated cholecystokinin-8 reduces meal size and prolongs the intermeal interval in male Sprague Dawley rats. Neuropeptides, 73, 57-65.
6. Mhalhal, T. R., Washington, M. C., Newman, K. D., Heath, J. C., & Sayegh, A. I. (2018). Combined gastrin releasing peptide-29 and glucagon like peptide-1 reduce body weight more than each individual peptide in diet-induced obese male rats. Neuropeptides, 67, 71-78.
7. Newman, K. D., Mhalhal, T. R., Washington, M. C., Heath, J. C., & Sayegh, A. I. (2017). Peptide Tyrosine Tyrosine 3-36 Reduces Meal Size and Activates the Enteric Neurons in Male Sprague–Dawley Rats. Digestive Diseases and Sciences, 62, 3350-3358.
8. Sayegh, A. I., Washington, M. C., Raboin, S. J., Aglan, A. H., & Reeve Jr, J. R. (2014). CCK-58 prolongs the intermeal interval, whereas CCK-8 reduces this interval: not all forms of cholecystokinin have equal bioactivity. Peptides, 55, 120-125.
9. Washington, M. C., Mhalhal, T. R., & Sayegh, A. I. (2016). The BB2 receptor antagonist BW2258U89 attenuates the feeding responses evoked by exogenous gastrin releasing peptide-29. Hormones and behavior, 85, 1-4.
10. Washington, M. C., Mhalhal, T. R., Johnson-Rouse, T., Berger, J., Heath, J., Seeley, R., & Sayegh, A. I. (2016). Roux-en-Y gastric bypass augments the feeding responses evoked by gastrin-releasing peptides. Journal of Surgical Research, 206(2), 517-524.
11. Sayegh, A. I., & Ritter, R. C. (2003). Morphology and distribution of nitric oxide synthase‐, neurokinin‐1 receptor‐, calretinin‐, calbindin‐, and neurofilament‐M‐immunoreactive neurons in the myenteric and submucosal plexuses of the rat small intestine. The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology: An Official Publication of the American Association of Anatomists, 271(1), 209-216.
12. Sullivan, C. N., Raboin, S. J., Gulley, S., Sinzobahamvya, N. T., Green, G. M., Reeve Jr, J. R., & Sayegh, A. I. (2007). Endogenous cholecystokinin reduces food intake and increases Fos-like immunoreactivity in the dorsal vagal complex but not in the myenteric plexus by CCK1 receptor in the adult rat. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 292(3), R1071-R1080.
13. Larsen, C. J., Washington, M. C., & Sayegh, A. I. (2010). Cholecystokinin-8 increases the satiety ratio in diabetic rats more than cholecystokinin-33. Physiology & behavior, 101(5), 649-652.
14. Wright, S. A., Washington, M. C., Garcia, C., & Sayegh, A. I. (2012). Gastrin releasing peptide-29 requires vagal and splanchnic neurons to evoke satiation and satiety. Peptides, 33(1), 125-131.
15. Hunt, J. V., Washington, M. C., & Sayegh, A. I. (2012). Exenatide and feeding: possible peripheral neuronal pathways. Peptides, 33(2), 285-290.
16. Newman, K. D., Mhalhal, T. R., Washington, M. C., Heath, J. C., & Sayegh, A. I. (2017). Peptide Tyrosine Tyrosine 3-36 Reduces Meal Size and Activates the Enteric Neurons in Male Sprague–Dawley Rats. Digestive Diseases and Sciences, 62, 3350-3358.
17. Metcalf, S. A., Washington, M. C., Brown, T. A., Williams, C. S., Strader, A. D., & Sayegh, A. I. (2011). Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and-33. Peptides, 32(6), 1296-1302.
18. Raboin, S. J., Gulley, S., Henley, S. C., Chan, W. C., Esdaile, A. R., Jackson, C. A., ... & Sayegh, A. I. (2006). Effect of sympathectomy and demedullation on increased myenteric and dorsal vagal complex Fos-like immunoreactivity by cholecystokinin-8. Regulatory peptides, 134(2-3), 141-148.
19. Metcalf, S. A., Washington, M. C., Brown, T. A., Williams, C. S., Strader, A. D., & Sayegh, A. I. (2011). Ileal interposition attenuates the satiety responses evoked by cholecystokinin-8 and-33. Peptides, 32(6), 1296-1302.
20. Williams, K. E., Washington, M. C., Johnson-Rouse, T., Johnson, R. E., Freeman, C., Reed, C., ... & Sayegh, A. I. (2016). Exogenous glucagon-like peptide-1 acts in sites supplied by the cranial mesenteric artery to reduce meal size and prolong the intermeal interval in rats. Appetite, 96, 254-259.
21. Klein, T. B. G. (2012). Cunningham's Textbook of Veterinary Physiology-E-Book: Cunningham's Textbook of Veterinary Physiology-E-Book. Elsevier Health Sciences.

Profile Details

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