Prof. Mohamed Chahine
Laval University, Canada
Professor
Email: [email protected]
Qualifications
1984-1987 Ph.D., Cardiac Cellular and Molecular Biology
1982-1983 M.Sc., Animal Physiology
Publications (Selected)
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Lizot, G., Bescond, J., De Koninck, Y., Chahine, M., Bois, P., Faivre, J. F., & Chatelier, A. (2025). Excitability properties of cardiac calbindin neurons: Identifying a unique neuronal population. Heart Rhythm.
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Hammache, M., Benchekroun, S., Alamri, A., Jalouli, M., Yousry A. Mohamed, M., Boufahja, F., ... & Semlali, A. (2024). Modulation of signature cancer-related genes in oral cancer cells (Ca9-22) by anethole treatment: Insights into therapeutic potential. Plos one, 19(12), e0315085.
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Kadala, A., Kaabeche, M., Charreton, M., Mutterer, J., Pélissier, M., Cens, T., ... & Collet, C. (2024). Unravelling impacts of the insecticide deltamethrin on neuronal sodium channels in honey bees: Molecular insights and behavioural outcomes. Chemosphere, 369, 143852.
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Sleiman, Y., Reisqs, J. B., Tan, R. B., Cecchin, F., Chahine, M., & Boutjdir, M. (2024). Generation of an iPSC cell line (VANYHHi001-A) from a patient with cardiac arrythmias carrying CACNA1D, SCN5A, and DSP variants. Stem Cell Research, 81, 103608.
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Ng, A. C. H., Chahine, M., Scantlebury, M. H., & Appendino, J. P. (2024). Channelopathies in epilepsy: an overview of clinical presentations, pathogenic mechanisms, and therapeutic insights. Journal of Neurology, 271(6), 3063-3094.
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Djemai, M., Jauvin, D., Poulin, H., Chapotte-Baldacci, C. A., & Chahine, M. (2024). Generation of a patient-specific iPSC cell line with cardiac arrhythmias and dilated cardiomyopathy (CBRCULi016-A), an isogenic control (CBRCULi016-A-1), and a paternal control (CBRCULi017-A). Stem Cell Research, 75, 103308.
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Chapotte-Baldacci, C. A., Pierre, M., Djemai, M., & Chahine, M. (2024). Characterizing ionic currents of atrial-like and ventricular-like hiPSC-cardiomyocytes. Biophysical Journal, 123(3), 384a.
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Chapotte-Baldacci, C. A., Pierre, M., Djemai, M., Pouliot, V., & Chahine, M. (2023). Biophysical properties of NaV1. 5 channels from atrial-like and ventricular-like cardiomyocytes derived from human induced pluripotent stem cells. Scientific reports, 13(1), 20685.
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Pierre, M., Djemai, M., Chapotte-Baldacci, C. A., Pouliot, V., Puymirat, J., Boutjdir, M., & Chahine, M. (2023). Cardiac involvement in patient-specific induced pluripotent stem cells of myotonic dystrophy type 1: unveiling the impact of voltage-gated sodium channels. Frontiers in Physiology, 14, 1258318.
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Djemai, M., Cupelli, M., Boutjdir, M., & Chahine, M. (2023). Optical mapping of cardiomyocytes in monolayer derived from induced pluripotent stem cells. Cells, 12(17), 2168.
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Zaveri, S., Srivastava, U., Qu, Y. S., Chahine, M., & Boutjdir, M. (2023). Pathophysiology of Cav1. 3 L-type calcium channels in the heart. Frontiers in Physiology, 14, 1144069.
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Jauvin, D., Pierre, M., Boutjdir, M., Puymirat, J., & Chahine, M. (2023). Generation of four myotonic dystrophy type 1 patient iPSC lines (CBRCULi002-A, CBRCULi003-A, CBRCULi004-A, CBRCULi005-A) and a control (CBRCULi001-A) derived from lymphoblastoids cell lines. Stem Cell Research, 67, 103037.
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Ait Benichou, S., Jauvin, D., de Serres-Bérard, T., Pierre, M., Ling, K. K., Bennett, C. F., ... & Puymirat, J. (2022). Antisense oligonucleotides as a potential treatment for brain deficits observed in myotonic dystrophy type 1. Gene Therapy, 29(12), 698-709.
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Sheta, R., Teixeira, M., Idi, W., Pierre, M., de Rus Jacquet, A., Emond, V., ... & Oueslati, A. (2022). Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons. Scientific Reports, 12(1), 17176.
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Benichou, A., Jauvin, D., Bennett, F., Rigo, F., Gourdon, G., Boutjdir, M., ... & Puymirat, J. (2022). Enhanced Delivery of Ligand-Conjugated Antisense Oligonucleotides (C16-HA-ASO) Targeting Dystrophia Myotonica Protein Kinase Transcripts for the Treatment of Myotonic Dystrophy Type 1. Human Gene Therapy, 33(15-16), 810-820.
Profile Details
WoS ResearcherID: GAU-8487-2022
https://cervo.ulaval.ca/en/profile/mohamed-chahine/
https://scholar.google.com/citations?user=ZeLD0bUAAAAJ&hl=fr
https://www.researchgate.net/profile/Mohamed-Chahine