Biography

Dr. Majella E. Lane

Department of Pharmaceutics

UCL School of Pharmacy, London, United Kingdom

Associate Professor


Email: [email protected]


Qualifications

1997 Ph.D., Trinity College, Dublin

1994 B.Sc., Trinity College, Dublin


Publications(selected)

  1. Lane, M. E. (2024). In vitro permeation testing for the evaluation of drug delivery to the skin. European Journal of Pharmaceutical Sciences, 201, 106873.
  2. Fluhr, J. W., Moore, D. J., Lane, M. E., Lachmann, N., & Rawlings, A. V. (2024). Epidermal barrier function in dry, flaky and sensitive skin: A narrative review. Journal of the European Academy of Dermatology and Venereology, 38(5), 812-820.
  3. Rahma, A., & Lane, M. E. (2022). Skin barrier function in infants: update and outlook. Pharmaceutics, 14(2), 433.
  4. Cristofoli, M., Kung, C. P., Hadgraft, J., Lane, M. E., & Sil, B. C. (2021). Ion pairs for transdermal and dermal drug delivery: a review. Pharmaceutics, 13(6), 909.
  5. Iliopoulos, F., Caspers, P. J., Puppels, G. J., & Lane, M. E. (2020). Franz cell diffusion testing and quantitative confocal raman spectroscopy: In vitro-in vivo correlation. Pharmaceutics, 12(9), 887.
  6. Zhang, Y., Lane, M. E., Hadgraft, J., Heinrich, M., Chen, T., Lian, G., & Sinko, B. (2019). A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model. International Journal of Pharmaceutics, 556, 142-149.
  7. Iliopoulos, F., Sil, B. C., Moore, D. J., Lucas, R. A., & Lane, M. E. (2019). 3-O-ethyl-l-ascorbic acid: Characterisation and investigation of single solvent systems for delivery to the skin. International Journal of Pharmaceutics: X, 1, 100025.
  8. Khan, M. N., Lane, M. E., McCarron, P. A., & Tambuwala, M. M. (2018). Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function. Inflammopharmacology, 26, 561-569.
  9. McAleer, M. A., Jakasa, I., Raj, N., O'Donnell, C. P., Lane, M. E., Rawlings, A. V., ... & Irvine, A. D. (2018). Early‐life regional and temporal variation in filaggrin‐derived natural moisturizing factor, filaggrin‐processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis. British journal of dermatology, 179(2), 431-441.
  10. Khan, M. N., Haggag, Y. A., Lane, M. E., McCarron, P. A., & Tambuwala, M. M. (2018). Polymeric nano-encapsulation of curcumin enhances its anti-cancer activity in breast (MDA-MB231) and lung (A549) cancer cells through reduction in expression of HIF-1α and nuclear p65 (REL A). Current drug delivery, 15(2), 286-295.
  11. Hadgraft, J., & Lane, M. E. (2016). Drug crystallization–implications for topical and transdermal delivery. Expert opinion on drug delivery, 13(6), 817-830.
  12. Luo, L., Patel, A., Sinko, B., Bell, M., Wibawa, J., Hadgraft, J., & Lane, M. E. (2016). A comparative study of the in vitro permeation of ibuprofen in mammalian skin, the PAMPA model and silicone membrane. International Journal of Pharmaceutics, 505(1-2), 14-19.
  13. Hadgraft, J., & Lane, M. E. (2016). Advanced topical formulations (ATF). International Journal of Pharmaceutics, 514(1), 52-57.
  14. Lane M. E. (2013), The transdermal delivery of fentanyl, European Journal of Pharmaceutics and Biopharmaceutics, 84, 3, 449-455.
  15. Watkinson A.C., Bunge A. L., Hadgraft J. and Lane M. E. (2013), Nanoparticles do not penetrate human skin–a theoretical perspective, Pharmaceutical Research, 30, 8, 1943-1946.
  16. Oliveira G., Hadgraft J., and Lane M.E. (2012), The role of vehicle interactions on permeation of an active through model membranes and human skin, International Journal of Cosmetic Science, 34, 6, 496-501.
  17. Oliveira G., Hadgraft J., and Lane M.E. (2012), The influence of volatile solvents on transport across model membranes and human skin, International Journal of Pharmaceutics, 431, 1, 38-49.
  18. Oliveira G., Hadgraft J., and Lane M.E. (2004), Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning,International Journal of Pharmaceutics, 420, 2, 216- 222.


Profile Details

https://iris.ucl.ac.uk/iris/browse/profile?upi=MLANE
https://orcid.org/0000-0002-7904-3614
https://www.researchgate.net/scientific-contributions/Majella-E-Lane-10535043
https://www.scilit.com/scholars/1557101

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