Biography

Prof. Ming-Liang He

City University of Hong Kong, China


Email: [email protected]


Qualifications

2000 Post Doc., Roswell Park Cancer Institute; Washington University School of Medicine at St. Louis, USA

1995 Ph.D., The Shanghai Institute of Biochemistry, China

1988 B.Sc., Sichuan University, China


Publications (Selected)

  1. Feng, Y., Wang, X., Chen, C., et al. (2026). Carbon quantum dots assisted virus tracking: From skin to brain. Advanced Materials, 38(6), 2508464.
  2. Leung, S. H. Y., Wang, D., Wan, Q., et al. (2026). Challenges and beyond: Targeting hypoxia-inducible factors for anti-tumor immunity restoration. Hypoxia & Medicine, 1(1), 1.
  3. Han, Z., Duan, M., Wan, Q., et al. (2026). A binary catalytic system for enantioselective annulation of 3-amino oxetanes with isocyanates leading to antiviral chiral 2-iminothiazolidines. ACS Catalysis, 16(2), 1585–1593.
  4. Pei, X., Liu, Z., Tang, L., et al. (2025). Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116+ pericytes in cancer metastasis. Nature Genetics, 57(10), 2494–2508.
  5. Wan, Q., Zhu, L., Chen, C., et al. (2025). PIM1 attenuates innate immunity to foster coronavirus replication through ubiquitin ligase β-TrCP-mediated IFNAR1 degradation. Advanced Science, 12(37), e03487.
  6. Li, S. J., Liang, Z. R., Liu, Z. C., et al. (2025). LIMK1 as a novel kinase of β-catenin promotes esophageal cancer metastasis by cooperating with CDK5. Advanced Science, 12(29), e03223.
  7. Zhan, Y. J., Deng, C. M., Tang, L., et al. (2025). NAT10 increases lysosomal acidification to promote esophageal cancer metastasis via ac4C acetylation of ATP6V0E1 mRNA. Advanced Science, 12(31), e02931.
  8. Faleti, O. D., Alsaadawe, M., Long, J., et al. (2025). Dimethyl fumarate abrogates hepatocellular carcinoma growth by inhibiting Nrf2/Bcl-xL axis and enhances sorafenib’s efficacy. Scientific Reports, 15(1), 16724.
  9. Tang, L., Peng, S. C., Zhuang, X. W., et al. (2025). Tumor metastasis: mechanistic insights and therapeutic intervention. MedComm–Oncology, 4(1), e70012.
  10. Wu, M., Li, W., Leung, H., et al. (2025). Targeting WDPF domain of Hsp27 achieves a broad spectrum of antiviral. MedComm, 6(3), e70032.
  11. Wang, Y., Song, D., Li, Y., et al. (2024). Erp57 facilitates ZIKV-induced DNA damage via NS2B/NS3 complex formation. Emerging Microbes & Infections, 13(1), 2417864.
  12. Wu, M., Wan, Q., Dan, X., et al. (2024). Targeting Ser78 phosphorylation of Hsp27 achieves potent antiviral effects against enterovirus A71 infection. Emerging Microbes & Infections, 13(1), 2368221.
  13. Xie, Y. X., Wang, L., Zhou, Z. H., et al. (2024). m6A RNA methyltransferase METTL16 induces Cr (VI) carcinogenesis and lung cancer development through glutamine biosynthesis and GLUL expression. Journal of Hazardous Materials, 480, 136093.
  14. Cao, C., Hou, C., Wang, X., et al. (2024). Liquid metal-enhanced highly adhesive electrodes for multifunctional epidermal bioelectronics. Advanced Functional Materials, 34(40), 2403671.
  15. Wang, Y., Chen, P., & He, M. L. (2024). Targeting lipid metabolism for better management of coronavirus SARS-COV-2 infections: intervention, antiviral drug development, and challenges. Journal of Cellular Signaling, 5(2), 91–95.
  16. Li, H., Wang, X., Wang, Y., et al. (2024). Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity. Signal Transduction and Targeted Therapy, 8(1), 374.
  17. Lu, G., Chen, C., Wang, Z., et al. (2023). High-performance supramolecular organogel adhesives for antimicrobial applications in diverse conditions. ACS Applied Materials & Interfaces, 15(37), 44194–44204.
  18. Wang, L., Zhou, Z. H., Xie, Y. X., et al. (2023). Dysregulation of MiR-199a/IL8 pathway in chronic Cr (VI)-induced tumor growth and angiogenesis. Ecotoxicology and Environmental Safety, 262, 115155.
  19. Shao, X., Yao, C., Ding, Y., et al. (2023). The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections. Genes & Diseases, 10(5), 2049–2063.
  20. Deng, Z., Li, H., Chen, S., et al. (2023). Near-infrared-activated anticancer platinum (IV) complexes directly photooxidize biomolecules in an oxygen-independent manner. Nature Chemistry, 15(7), 930–939.
  21. Chen, P., Wu, M., He, Y., et al. (2023). Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection. Signal Transduction & Targeted Therapy, 8(1), 237.
  22. Hu, H., Feng, Y., & He, M. L. (2023). Targeting type I interferon induction and signaling: how Zika virus escapes from host innate immunity. International Journal of Biological Sciences, 19(10), 3015.
  23. Veremeyko, T., Rongcai Jiang, R., He, M., et al. (2023). Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of... Frontiers in Cellular Neuroscience, 17, 1170031.
  24. Xie, Y. X., Zhou, Z. H., Liu, S. W., et al. (2023). microRNA-497 slows esophageal cancer development and reverses chemotherapy resistance through its target QKI. Aging (Albany NY), 15(9), 3791.
  25. Xu, W. W., Liao, L., Dai, W., et al. (2023). Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis. EBioMedicine, 92, 104587.


Profile Details
https://scholars.cityu.edu.hk/en/persons/minglihe/
https://scholar.google.com/citations?user=BeBfIoAAAAAJ&hl=zh-CN
https://www.researchgate.net/profile/Ming-Liang-He

WOS ResearcherID: GDQ-0418-2022

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