Dr. Xinbo Li

Casey Eye Institute

Oregon Health and Science University, USA
Assistant Professor

Email: [email protected]

Qualifications

1995-1998 Ph.D., Shanghai Medical University, Shanghai, China

1992-1995 M.Sc., Shanghai Medical University, Shanghai, China

Publications (Selected)

1. Chen, R., Chen, F., Tan, R., Shen, B., Yang, L., Wang, Y., ... & Zhao, X. (2025). CXCL14–CXCR4-mediated platelet migration across the blood–brain barrier and subsequent microglia and astrocyte activation in arterial baroreflex dysfunction. Journal of Neurorestoratology, 100255.
2. Xu, Y., Wang, Y., Qi, R., Li, K., Wang, X., Li, X., & Shi, B. (2024). Role of connexin 32 in the directional differentiation of induced pluripotent stem cells into hepatocytes. International Journal of Medical Sciences, 21(3), 508.
3. Qi, R., Bai, Y., Li, K., Liu, N., Xu, Y., Dal, E., ... & Shi, B. (2023). Cancer-associated fibroblasts suppress ferroptosis and induce gemcitabine resistance in pancreatic cancer cells by secreting exosome-derived ACSL4-targeting miRNAs. Drug Resist Updat, 68(100960), 10-1016.
4. Shi, Y., Li, X., & Yang, J. (2022). Cx43 upregulation in HUVECs under stretch via TGF-β1 and cytoskeletal network. Open Medicine, 17(1), 463-474.
5. Shi, Y., Li, X., & Yang, J. (2022). Mutations of CX46/CX50 and cataract development. Frontiers in molecular biosciences, 9, 842399.
6. Li, X. (2021). Seeing Is Believing: Gap Junctions in Motion. Biology, 10(6), 494.
7. Shi, Y., Li, R., Yang, J., & Li, X. (2020). No tight junctions in tight junction protein-1 expressing HeLa and fibroblast cells. International Journal of Physiology, Pathophysiology and Pharmacology, 12(2), 70.
8. Li, X., Nagy, J. I., Li, D., Acott, T. S., & Kelley, M. J. (2020). Gap junction connexin43 is a key element in mediating phagocytosis activity in human trabecular meshwork cells. International Journal of Physiology, Pathophysiology and Pharmacology, 12(1), 25.
9. Li, X., Acott, T. S., Nagy, J. I., & Kelley, M. J. (2020). ZO-1 associates with α3 integrin and connexin43 in trabecular meshwork and Schlemm’s canal cells. International Journal of Physiology, Pathophysiology and Pharmacology, 12(1), 1.
10. Zhou, R., Xie, X., Li, X., Qin, Z., Wei, C., Liu, J., & Luo, Y. (2020). The triggers of the cGAS-STING pathway and the connection with inflammatory and autoimmune diseases. Infection, Genetics and Evolution, 77, 104094.
11. Li, X. (2019). Gap junction protein connexin43 and tunneling nanotubes in human trabecular meshwork cells. International Journal of Physiology, Pathophysiology and Pharmacology, 11(5), 212.
12. Li, X., Wang, Y., & Zhao, X. (2019). Upregulation of retinal gap junction protein Cx36 expression in glaucoma is mediated by reducing LNX2 degradation of Cx36. Investigative Ophthalmology & Visual Science, 60(9), 616-616.
13. Lynn, B. D., Li, X., Hormuzdi, S. G., Griffiths, E. K., McGlade, C. J., & Nagy, J. I. (2018). E3 ubiquitin ligases LNX 1 and LNX 2 localize at neuronal gap junctions formed by connexin36 in rodent brain and molecularly interact with connexin36. European Journal of Neuroscience, 48(9), 3062-3081.
14. Li, X., Wang, Y., Li, D., Acott, T. S., & Kelley, M. J. (2018). Connexin43 is a key element for differentiation of iPSCs to trabecular meshwork like cells. Investigative Ophthalmology & Visual Science, 59(9), 3530-3530.
15. Shi, B., Xue, M., Wang, Y., Wang, Y., Li, D., Zhao, X., & Li, X. (2018). An improved method for increasing the efficiency of gene transfection and transduction. International journal of physiology, pathophysiology and pharmacology, 10(2), 95.
16. Li, X., Acott, T. S., & Kelley, M. J. (2016). Gap and tight intercellular junctions in trabecular meshwork and Schlemm’s canal cells. Investigative Ophthalmology & Visual Science, 57(12), 4678-4678.
17. Acott, T. S., Kelley, M. J., Keller, K. E., Vranka, J. A., Abu-Hassan, D. W., Li, X., ... & Bradley, J. M. (2016). IOP Homeostasis-Why most people do not ever develop glaucoma. Glaucoma research and clinical advances, 2018, 87-98.
18. Knepper, P. A., & Samples, J. R. (Eds.). (2016). Glaucoma research and clinical advances 2016 to 2018 (Vol. 1). Kugler Publications.
19. Abu-Hassan, D. W., Li, X., Ryan, E. P., Acott, T. S., & Kelley, M. J. (2016). Induced pluripotent stem cells restore function in a human cell loss model of open-angle glaucoma. J Clin Exp Ophthalmol, 7(531), 2.
20. Li, X., Phan, K., Acott, T. S., & Kelley, M. J. (2015). Involvement of ATP binding cassette transporter 1 (ABCA1) in the regulation of outflow facility. Investigative Ophthalmology & Visual Science, 56(7), 3282-3282.

Profile Details

https://www.ohsu.edu/people/xin-li

https://www.researchgate.net/profile/Xinbo-Li-3

https://scholar.google.com/citations?user=r2UJ9-AAAAAJ&hl=en

WoS ResearcherID: JDW-2877-2023