Biography

Prof. Andrei P. Surguchov

Kansas University Medical Center, USA


Email: [email protected]


Qualifications

Ph.D., Molecular Biology, Cardiology Research Center, Russia

M.Sc., Molecular Biology, Moscow State University, Russia

B.Sc., Biochemistry, Moscow State University, Russia


Publications (selected)

  1. Surguchov, A., & Surguchev, A. A. (2024). Association between Parkinson’s disease and cancer: new findings and possible mediators. International Journal of Molecular Sciences, 25(7), 3899.
  2. Surguchov, A. (2023). α-Synuclein and mechanisms of epigenetic regulation. Brain Sciences, 13(1), 150.
  3. Surguchov, A., Emamzadeh, F. N., Titova, M., & Surguchev, A. A. (2023). Controversial properties of amyloidogenic proteins and peptides: New data in the COVID era. Biomedicines, 11(4), 1215.
  4. Surguchov, A., & Surguchev, A. (2022). Synucleins: new data on misfolding, aggregation and role in diseases. Biomedicines, 10(12), 3241.
  5. Surguchov, A. (2021). Biomarkers in Parkinson’s disease. In Neurodegenerative diseases biomarkers: Towards translating research to clinical practice (pp. 155-180). New York, NY: Springer US.
  6. Surguchov, A. (2021). Invertebrate models untangle the mechanism of neurodegeneration in Parkinson’s disease. Cells, 10(2), 407.
  7. Surguchov, A., Bernal, L., & Surguchev, A. A. (2021). Phytochemicals as regulators of genes involved in synucleinopathies. Biomolecules, 11(5), 624.
  8. Surguchov, A. (2020). Caveolin: a new link between diabetes and AD. Cellular and molecular neurobiology, 40(7), 1059-1066.
  9. Surguchev, A. A., Emamzadeh, F. N., & Surguchov, A. (2019). Cell responses to extracellular α-synuclein. Molecules, 24(2), 305.
  10. Emamzadeh, F. N., & Surguchov, A. (2018). Parkinson’s disease: biomarkers, treatment, and risk factors. Frontiers in neuroscience, 12, 612.
  11. Surguchev, A. A., & Surguchov, A. (2017). Synucleins and gene expression: ramblers in a crowd or cops regulating traffic?. Frontiers in molecular neuroscience, 10, 224.
  12. Surguchov, A., Surgucheva, I., Sharma, M., Sharma, R., & Singh, V. (2017). Pore-forming proteins as mediators of novel epigenetic mechanism of epilepsy. Frontiers in Neurology, 8, 3.
  13. Surgucheva I, Ninkina N, Buchman VL, Grasing K, A. Surguchov. 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular Molecular Neurobiology, 25, 6, 1051-1066.
  14. Surgucheva, B. Yue, BC Park, S Tomarev and A. Surguchov. 2005. Interaction of myocilin with gamma-synuclein and its role in neurodegeneration in glaucoma. Cellular Molecular Neurobiology, 25, 6, 1009-1033.
  15. Snyder HM, Mensah K, Surgucheva I, Festoff B, Surguchov A, Wolozin B. 2005. b-Synuclein prevents proteasomal inhibition by α-synuclein but not γ-synuclein. J Biol Chem, 280(9):7562-9.
  16. Maurage CA, Ruchoux MM, De Vos R, Surguchov A, Destee A. 2004. Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? Ann Neurol. 54(4):542-7.
  17. Surgucheva I, Sivak, JM, Fini ME, Palazzo RE and Surguchov AP. 2003. Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 410:167-176.
  18. Surgucheva I., McMahan B, F. Ahmed , Tomarev S, Wax MB, Surguchov A. 2002. Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve. J Neurosci Res, 68: 97-106.
  19. Pronin AN, Morris AJ, Surguchov A, Benovic JL. 2000. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem., 275, 26515-26522
  20. A Surguchov, RE. Palazzo, and I Surgucheva. 2001. Gamma synucleins: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228
  21. Surguchov, B. McMahon, E. Masliah, I. Surgucheva. 2001. Synucleins in ocular tissues. J Neurosci Res, 65, 68-77
  22. Surguchov, I.Surgucheva, K. Howes, W. Baehr. 1999. Synoretin - a new retina protein belonging to the synuclein family. Mol Cell Neurosci, 13, 95-103.
  23. I.G. Surgucheva, W. Baehr, A. Surguchov. 1997. Differential effect of expression of heterologous genes in baculovirus transfer vector on the level of baculovirus protein expression. Mol Biol of the Cell, 139, 806
  24. A.P. Surguchov, G.P. Page, L. Smith, W. Patsch, E. Boerwinkle. 1996. Polymorphic markers in apo-lipoprotein C-III gene flanking regions and hyper- lipoproteinemia. Arteriosclerosis, Thrombosis and Vascular Biology, v.16, 8, pp.941-948
  25. Y.Ch. Lin-Lee, S. Soyal, S. Sanders, A. Surguchov, W. Patsch, 1995 Thyroid hormone influences conditional transcript elongation of the apolipoprotein A-I gene in rat liver. J. Lipid Research , v. 36, pp. 1586-1595.
  26. A.P. Surguchov, S. Liu, W. Patsch. 1995. Simple non-radioactive methods of analysis of polymorphic markers flanking human apolipoprotein C-III gene. Disease Markers, v. 12, pp. 167 - 174
  27. A.P. Surguchov, E. Boerwinkle, R. Sharett, W. Patsch. 1994. Apolipoprotein E genotype and plasma lipid transport : insight into the role of the E4 allele from populational studies. Atherosclerosis, v.106, p.119
  28. A.P. Surguchov . 1991. Migration of promoter elements between genes : a role in transcriptional regulation and evolution. Biomedical Sciences (Turpin Transactions Ltd., Pion Ltd.) , v. 2, pp. 22 - 28
  29. A.P. Surguchov. 1990. Apolipoprotein gene family : organization of upstream elements and regulation of gene expression. Biomedical Sciences, Turpin Transactions Ltd., Pion Ltd., v. 1, No. 4, pp. 344 - 354
  30. A.B. Sudarikov and A.P. Surguchov. 1988. Probe for rabbit apolipoprotein B gene. Nucleic Acids Research, v.16, 16, p. 8187
  31. A.P. Surguchov. 1988. Omnipotent nonsense suppressors : new clues to an old puzzle. Trends in Biochemical Sciences (TIBS), v. 13, 4, pp. 120 - 123
  32. A.P. Surguchov. 1987. Common genes for mitochondrial and cytoplasmic proteins. Trends in Biochemical Sciences (TIBS). v. 12, 9, pp. 335 - 339
  33. V.A. Kosykh, E.A. Podrez, A.B. Novikov, A.P.Surguchov, V.N. Smirnov.1988. VLDL apoprotein secretion and apoB mRNA level in primary cultures of cholesterol loaded rabbit hepatocytes. FEBS Letters, v. 232, 1, pp. 103 - 106
  34. V.A. Kosykh, A.P. Surguchov, E.E. Podrez, V.N. Smirnov. 1988. 7-ketocholesterol inhibits VLDL secretion by cultured human and rabbit hepatocytes. Biochim Biophys Res Comm 153, 3, pp. 1116 - 1122
  35. Kushnirov V.V., Ter-Avanesyan, M.D.,Surguchov A.P., V.N. Smirnov, S.G. Inge-Vechtomov. 1988. Nucleotide sequence of the sup2 gene of yeast S. cerevisiae. Gene, 66, pp. 45 - 54
  36. Kushnirov, V.V., Ter-Avanesyan, M.D., Surguchov, A.P., Smirnov, V.N., Inge-Vechtomov, S.G. 1987. Localization of possible functional domains in sup2 gene product of the yeast S. cerevisiae. FEBS Letters, 215, 2, pp.257 - 260
  37. A.P. Surguchov, M.V. Telkov and V.N. Smirnov. 1986. Absence of structural homology between sup1 and sup2 genes of yeast S. cerevisiae and identification of their transcripts. FEBS Letters, 206,1, 147 - 150


Profile Details

https://www.kumc.edu/school-of-medicine/academics/departments/neurology/faculty.html
https://scholar.google.com/citations?user=BsT6G3cAAAAJ&hl=en
https://www.researchgate.net/profile/Andrei-Surguchov

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