Prof. Saad Usmani

University of Arkansas, USA

Email: [email protected]

Qualifications

1997 M.B.B.S., Allama Iqbal Medical College

1997 B.Sc., University of Punjab

Publications (selected)

1. Usmani SZ, Shahid Z. An Overview of Postmenopausal Osteoporosis. Pak J Med Sci, July-Sept 2004; 20; 270-5
2. Merajver SD, Usmani SZ. Multifaceted role of Rho proteins in angiogenesis. J Mammary Gland Biol Neoplasia. 2005; 10:291-8.
3. Halaweh O, Usmani SZ, Bloom R. Chemotherapy Induced Thymus Hyperplasia Mimics Recurrence of Cancer. Breast J. 2006; 12:381-2.
4. Yunus SA, Usmani SZ, Ahmed S, Shahid Z. Renal Involvement in Non-Hodgkin‟s lymphoma-the Shaukat Khanum experience. Asian Pac J Cancer Prev. 2007; 8:249-52
5. Usmani SZ, Shahid Z, Nasser K. J Nephrol. Can Pneumococcus cause Post-Infectious Glomerulonephritis in Adults? 2007; 20:99-102.
6. Halaweh O, Usmani SZ, Abouasaleh R. Barrett‟s Esophagitis Related Tracheoesophageal Fistula-The Diagnostic Value of Persistent Air Leak in the Ventilated Setting. McGill J Med. 2007; 10:96-8
7. Usmani SZ, Shahid Z, Saleh H, Nasser KA. Myeloid sarcoma presenting as acute renal failure and bilateral ureteral obstruction- a very rare presentation. Am J Med Sci. 2007; 334:136-8
8. Usmani SZ, Sahay T, Eisenberg L. Angioimmunoblastic T-cell lymphoma in evolution- a case report. Adv Ther. 2007; 24: 814-8
9. Usmani SZ, Ding L, Abu-Rashed AH, Saleh HA. Duodenal MALT lymphoma presenting with obstructive jaundice: report of a case and review of the literature. J Gastrointest Cancer. 2007;38:28-31
10. Usmani SZ, Appel J, Shahid Z, Saleh H. Spontaneous Tumor Lysis Syndrome and Secondary Thrombotic Thrombocytopenic Purpura in Early Stage Colorectal Cancer. Chin J of Clin Oncol. 2008; 5:150-3
11. Sharma R, Usmani SZ, Siegel R. Primary Squamous Cell Carcinoma of breast in background of Phyllodes tumor- A Case Report. Conn Med. 2009; 73:341-3.
12. Usmani SZ, Bona RD, Li Z. 17-AAG: From bench to bedside. Curr Mol Med. 2009; 9:654-64.
13. Usmani SZ, Pazooki M, Bilgrami SF. Small Cell Carcinoma of the Gall Bladder: Role of Adjuvant Therapy. J Gastrointest Cancer 2010;41:84-7. 14. Jabbour N, DiGiuseppe JA, Usmani S, Tannenbaum S. Copper deficiency as a cause of reversible anemia and neutropenia. Conn Med. 2010;74(5):261-3 15. Usmani SZ, Tannenbaum S, Hegde P. Emperipolesis in Giant Cell Carcinoma of the Lung. Comm Oncol 2010; 7:233–235.
14. Usmani SZ, Yunus SA, Jamal Y. Overview of CML in Pakistan in the pre-Imatinib era. Asian Pac J Cancer Prev 2010: 10;1039-1040 17. Usmani SZ, Bona RD, Chiosis G, Li Z. The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1. J Hematol Oncol. 2010 ;3:40
15. Usmani SZ, Sexton R, Crowley J, Barlogie B. Autologous Stem Cell Transplantation as a Care Option for Waldenstrom‟s Macroglobulinemia. Clin Lymphoma Myeloma Leuk 2011; 11:139-42.
16. Shaugnessy J, Qu P, Usmani SZ, Tian E, VanRhee F, Anaissie E, Nair B, Waheed S, AlSayed Y, Crowley J, Barlogie B. High PSMD4 Expression Levels in Plasma Cells Identified via Bortezomib Test-Dosing are Linked to Poor Prognosis in Untreated Multiple Myeloma. Blood 2011;118:3512-24.
17. Usmani SZ, Chiosis G, Bona RD. HSP90 Inhibitors as Therapy for Multiple Myeloma. Clin Lymphoma Myeloma Leuk 2011;S1;77-81.
18. Papanikolaou X, Barlogie B, Usmani SZ. Therapy-related Myeloid Malignancies in Myeloma. Mediterr J Hematol Infect Dis 2011, 3: e2011047
19. Ahmed N, Usmani SZ, Jabbour N, Hegde U. Acute Psychosis After Paclitaxel Infusion. Conn Med. 2011;75:465-466.
20. Muzaffar J, Katragadda L, Javed A, Restrepo A, Grazzuitti M, Anaissie E, Usmani SZ. Rituximab and Intravenous immunoglobulin (IVIG) for the management of Acquired Factor VIII Inhibitor in Multiple Myeloma: case report and review of literature. Int J Hematol. 2012; 95(1):102-6.
21. Richardson PG, Delforge M, Beksac M, Wen P, Jongen JL, Sezer O, Terpos E, Munshi N, Palumbo A, Rajkumar SV, Harousseau JL, Moreau P, Avet-Loiseau H, Lee JH, Cavo M, Merlini G, Voorhees P, Chng WJ, Mazumder A, Usmani S, Einsele H, Comenzo R, Orlowski R, Vesole D, Lahuerta JJ, Niesvizky R, Siegel D, Mateos MV, Dimopoulos M, Lonial S, Jagannath S, Bladé J, Miguel JS, Morgan G, Anderson KC, Durie BG, Sonneveld P. Management of treatment-emergent peripheral neuropathy in multiple myeloma. IMWG Guidelines. Leukemia. 2012;26(4):595-608.
22. Usmani SZ, Nair B, Qu P, Hansen E, Petty N, Zhang Q, Waheed S, Shaughnessy JD, Alsayed Y, Heuck CJ, Van Rhee F, Milner T, Hoering A, Szymonifka J, Sexton R, Swayer J, Losbach R, Crowley J, Barlogie B. Primary Plasma Cell Leukemia: Clinical and Laboratory Presentation and Clinical Outcome with Total Therapy Protocols. Leukemia. 2012 . doi: 10.1038/leu.2012.107. [Epub ahead of print]
23. Usmani SZ, Sexton R, Hoering A, Heuck C, Nair B, Waheed S, AlSayed Y, Petty N, Crowley J, Barlogie B. Second Malignancies in Total Therapy Trials for Newly Diagnosed Multiple Myeloma: Influence of Lenalidomide Versus Thalidomide in Maintenance Phases. Blood 2012. doi:10.1182/blood-2012-04-421883. [Epub ahead of print]
24. Usmani SZ , Crowley J, Hoering A, Sexton R, Waheed S, Nair B, AlSayed Y, van Rhee F, Barlogie B. Improvement in Long Term Outcomes with Successive Total Therapy Trials for Multiple Myeloma: Are Patients Now Being Cured? Leukemia 2012 Jun 18. doi: 10.1038/leu.2012.160. [Epub ahead of print]
25. Usmani SZ, Mitchell A, Szymonifka J, Qu P, Weed M, Shaugnessy J, Nair B, Waheed S, AlSayed Y, Crowley J, Barlogie B. Extramedullary Disease Portends Poor Prognosis in Multiple Myeloma and Is Overrepresented In High Risk Disease in the Era of Novel Agents. Hematologica 2012 Jun 11. [Epub ahead of print]
26. Waheed S, Mitchell A, Usmani S, Epstein J, Yaccoby S, Nair B, van Hemert R, Angtuaco E, Brown T, Bartel T, McDonald J, Anaissie E, van Rhee F, Shaughnessy JD, Crowley J, Barlogie B. Standard and novel imaging methods for multiple myeloma: correlates with prognostic laboratory variables including gene expression profiling data. Haematologica. 2012 Jun 24. [Epub ahead of print]
27. Heuck C, Szymonifka J, Hansen E, Shaughnessy JD, Usmani S, Van Rhee F, Anaissie E, Nair B, Waheed S, Alsayed Y, Petty N, Bailey C, Epstein J, Hoering A, Crowley JJ, Barlogie B. Thalidomide in Total Therapy 2 Overcomes Inferior Prognosis of Myeloma with Low Expression of the Glucocorticoid Receptor Gene NR3C1. Clin Cancer Res. 2012 Aug 1. [Epub ahead of print]
28. Singh Z, Medlin S, Usmani SZ. Molecular monitoring and treatment of Chronic Myeloid Leukemia. Clin Exp Pathol 2012 (In press)
29. Chauhan N, Barlogie B, Usmani SZ. Impediments to Curing Multiple Myeloma in the Year 2012. Int J Hematol Malig 2012 (In press)
30. Latif T, Chauhan N, Khan R, Moran A, Usmani SZ. Thalidomide and its analogues in the treatment of Multiple Myeloma. Exp Hematol Oncol 2012 (In press)
31. Muzaffar J, Katragadda L, Haider S, Abdallah A, Anaissie E, Usmani S. Waldenstrom‟s Macroglobulinemia Associated with Serum Amyloid A protein (SAA) Amyloidosis: Pitfalls in Diagnosis and Successful Treatment with Melphalan-based Auto Stem Cell Transplant. Acta Haematologica 2012 (In press)