Dr. Seema Agarwal

Georgetown University, USA

Email: [email protected]

Qualifications

1990  Ph.D., University of Allahabad, India

1984  M.Sc., University of Allahabad, India

1982  B.Sc., University of Allahabad, India

Publications (selected)

1. Simbulan-Rosenthal, C. M., Dougherty, R., & Vakili, S., et al. (2025). Simbulan-Rosenthal et al. CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis.(vol 11, 1490, 2019). Cancers, 17(21).
2. Simbulan-Rosenthal, C. M., Dougherty, R., & Vakili, S., et al. (2025). Correction: Simbulan-Rosenthal et al. CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and Metastasis. Cancers 2019, 11, 1490. Cancers, 17(21), Article 3436.
3. Lamichhane, A., Guragain, P., & Heiss, J., et al. (2025). Targeting CAFs-Mediated Stromal Signaling in a Patient-Derived Organotypic Colorectal Tumor Model. Molecular Cancer Therapeutics. Advance online publication.
4. Xiao, J., Mukherji, R., & Sidarous, G., et al. (2025). Longitudinal Circulating Tumor Cell Collection, Culture, and Characterization in Pancreatic Adenocarcinomas. Cancers, 17(3), Article 355.
5. Goyal, P., Ouf, M., & Agarwal, S., et al. (2024). Impact of next-generation sequencing in biliary tract cancer treatment. Journal of Clinical Oncology, 42(3_suppl), 560–560.
6. Xiao, J., Pohlmann, P. R., Schlegel, R., et al. (2023). State of the Art in the Propagation of Circulating Tumor Cells. In Circulating Tumor Cells: Advances in Liquid Biopsy Technologies (pp. 247–274). Springer.
7. O'Bryan, J., Yin, C., & Weinberg, B. A., et al. (2023). Phase II clinical trial of olaparib plus pembrolizumab in the treatment of patients with advanced biliary tract cancer. Journal of Clinical Oncology, 41(16_suppl), 4087–4087.
8. Pohlmann, P. R., Agarwal, S., & Schlegel, R. (2023). Methods for isolating and culturing tumor cells (U.S. Patent Application No. 17/921,606). U.S. Patent and Trademark Office.
9. Wakefield, L., Agarwal, S., & Tanner, K. (2023). Preclinical models for drug discovery for metastatic disease. Cell, 186(8), 1792–1813.
10. Xiao, J., Sharma, U., & Arab, A., et al. (2023). Propagated Circulating Tumor Cells Uncover the Potential Role of NFκB, EMT, and TGFβ Signaling Pathways and COP1 in Metastasis. Cancers, 15(6), Article 1831.
11. Mukherji, R., Suguru, S., & Xiao, J., et al. (2023). Success rates and clinicopathologic associations with experimental outcomes of a novel circulating tumor cell (CTC) technology in advanced colon cancer (CC) and pancreatic adenocarcinoma (PC). Journal of Clinical Oncology, 41(4_suppl), 805–805.
12. Lamichhane, A., Luker, G. D., & Agarwal, S., et al. (2023). Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells. Oncotarget, 14, Article 879.
13. Xiao, J., Sharma, U., & Arab, A., et al. (2022). Propagated circulating tumor cells uncovers the role of NFκB and COP1 in metastasis. bioRxiv. Advance online publication.
14. Xiao, J., McGill, J. R., & Nasir, A., et al. (2022). Identifying drivers of breast cancer metastasis in progressively invasive subpopulations of zebrafish-xenografted MDA-MB-231. Molecular Biomedicine, 3(1), 1–16.
15. Xiao, J., Schlegel, R., & Agarwal, S. (2022). Establishing circulating tumor cell-derived xenografts following a period of in vitro culture. Cancer Research, 82(12_Supplement), 5123–5123.
16. Yin, C., Armstrong, S. A., & Agarwal, S., et al. (2022). Phase II study of combination pembrolizumab and olaparib in patients with advanced cholangiocarcinoma: Interim results. Journal of Clinical Oncology, 40(4_suppl), 452–452.
17. Xiao, J., McGill, J. R., & Nasir, A., et al. (2021). Zebrafish xenografts to isolate unique human breast cancer metastatic cell populations. bioRxiv. Advance online publication.
18. Armstrong, S., Yin, C., & Agarwal, S., et al. (2021). PHASE II STUDY OF COMBINATION PEMBROLIZUMAB AND OLAPARIB IN PATIENTS WITH ADVANCED CHOLANGIOCARCINOMA: PRELIMINARY RESULTS. Hepatology, 74, 660A–661A.
19. Xiao, J., Pohlmann, P. R., & Isaacs, C., et al. (2021). Circulating Tumor Cells: Technologies and Their Clinical Potential in Cancer Metastasis. Biomedicines, 9(9), Article 1111.
20. Xiao, J., Kassner, J. D., & Stanton, K., et al. (2021). A robust method for expanding patient-derived circulating tumor cells ex vivo. Cancer Research, 81(13_Supplement), 585–585.

Profile Details

https://gufaculty360.georgetown.edu/s/contact/00336000014TMZ9AAO/seema-agarwal
https://cellmedicine.georgetown.edu/seemaagarwal/
https://scholar.google.com/citations?user=NdMH9lMAAAAJ&hl=en


WOS ResearcherID: GEH-3175-2022