Prof. Lei Xing

Department of Radiation Oncology

Stanford University, USA

Email: [email protected]

Qualifications

1997 Member of the Radiation Oncology faculty, Stanford University

1992 Ph.D., Johns Hopkins University

Publications (selected)

1. Wang Y, Zhao M, Xie H X, et al. Mitochondria-targeted gene delivery using fluorinated lipid nanoparticles to alleviate Leber’s hereditary optic neuropathy[J]. Nature Communications, 2025, 16(1): 10891.
2. Li X N, Lin Y P, Ma X X, et al. Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy[J]. Advanced Science, 2025: e12658.
3. Wang Y, Yu H Y, Yi Z J, et al. Super mitochondria-enriched extracellular vesicles enable enhanced mitochondria transfer[J]. Nature Communications, 2025, 16(1): 9448.
4. Wang Y, Zhang L F, Zhang J J, et al. Spontaneous Inflammation Resolution Inspired Nanoparticles Promote Neutrophil Apoptosis and Macrophage Efferocytosis for Acute Respiratory Distress Syndrome Treatment[J]. Advanced Healthcare Materials, 2025, 14(6): 2402421.
5. Li X N, Lin Y P, Han M M, et al. Modulating fibrotic mechanical microenvironment for idiopathic pulmonary fibrosis therapy[J]. Advanced Materials, 2024, 36(50): 2407661.
6. Zhang L F, Deng W Q, Wang X H, et al. Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk[J]. Advanced Science, 2025, 12(4): 2408898.
7. Wang Y, Liu N, Hu L, et al. Nanoengineered mitochondria enable ocular mitochondrial disease therapy via the replacement of dysfunctional mitochondria[J]. Acta Pharmaceutica Sinica B, 2024, 14(12): 5435-5450.
8. Wang H, Qi L, Han H, et al. Nanomedicine regulating PSC-mediated intercellular crosstalk: Mechanisms and therapeutic strategies[J]. Acta Pharmaceutica Sinica B, 2024, 14(11): 4756-4775.
9. Duan B W, Liu Y J, Li X N, et al. An autologous macrophage‐based phenotypic transformation‐collagen degradation system treating advanced liver fibrosis[J]. Advanced Science, 2024, 11(7): 2306899.
10. Sun Y, Xing L, Luo J, et al. A Pro‐Metastatic Derivatives Eliminator for In Vivo Dual‐Removal of Circulating Tumor Cells and Tumor‐Derived Exosomes Impedes their Biodistribution into Distant Organs[J]. Advanced Science, 2023, 10(34): 2304287.
11. Wang Y, Hu L F, Liu N H, et al. Suppression of mitochondrial heterogeneity via engineered mitochondria for reversion of mitochondrial disease-related phenotypes[J]. (No Title), 2022.
12. Zhang L F, Wang X H, Zhang C L, et al. Sequential nano-penetrators of capillarized liver sinusoids and extracellular matrix barriers for liver fibrosis therapy[J]. ACS nano, 2022, 16(9): 14029-14042.
13. Qi L Y, Wang Y, Hu L F, et al. Enhanced nuclear gene delivery via integrating and streamlining intracellular pathway[J]. Journal of Controlled Release, 2022, 341: 511-523.
14. Xing L, Liu X Y, Zhou T J, et al. Photothermal nanozyme-ignited Fenton reaction-independent ferroptosis for breast cancer therapy[J]. Journal of Controlled Release, 2021, 339: 14-26.
15. Lu Z, Liang D, Ping X, et al. 1D/2D heterostructures as ultrathin catalysts for hydrogen evolution reaction[J]. Small, 2020, 16(44): 2004296.
16. Fesmire C C, Petrella R A, Fogle C A, et al. Temperature dependence of high frequency irreversible electroporation evaluated in a 3D tumor model[J]. Annals of Biomedical Engineering, 2020, 48(8): 2233-2246.
17. Zhu Y, Xing L, Zheng X, et al. Amplification of tumor antigen presentation by NLGplatin to improve chemoimmunotherapy[J]. International Journal of Pharmaceutics, 2020, 573: 118736.
18. Liu L, Wu J, Wu L, et al. Phase-selective synthesis of 1T′ MoS2 monolayers and heterophase bilayers[J]. Nature materials, 2018, 17(12): 1108-1114.
19. Huang P, Yu G, Kapp D S, et al. Cumulative dose of radiation therapy of hepatocellular carcinoma patients and its deterministic relation to radiation-induced liver disease[J]. Medical Dosimetry, 2018, 43(3): 258-266.
20. Liu H, Dong P, Xing L. Using measurable dosimetric quantities to characterize the inter-structural tradeoff in inverse planning[J]. Physics in Medicine & Biology, 2017, 62(16): 6804.
21. Li D, Liu L, Chen J, et al. Augmenting atlas-based liver segmentation for radiotherapy treatment planning by incorporating image features proximal to the atlas contours[J]. Physics in Medicine & Biology, 2016, 62(1): 272.
22. Wang F Z, Xie Z S, Xing L, et al. Biocompatible polymeric nanocomplexes as an intracellular stimuli-sensitive prodrug for type-2 diabetes combination therapy[J]. Biomaterials, 2015, 73: 149-159.

Profile Details

https://med.stanford.edu/profiles/lei-xing

https://www.researchgate.net/profile/Lei-Xing-2

https://baike.baidu.com/item/%E9%82%A2%E7%A3%8A/65041182  

WoS ResearcherID: HJV-2705-2023