Department of Biochemistry and Molecular Biology
Louisiana State University Health Sciences Center, USA

Email: [email protected]

Qualifications

1994- 1997 Ph.D., Institute of Zoology, University of Salzburg, Austria

1984- 1987 M.S., Nanjing Agricultural, University, Nanjing, China

1980- 1984 B.S., Anhui Agricultural University, China

Publications (Selected)

1. Luo, Y., Liu, L., Wu, Y., Singh, K., Su, B., Zhang, N., ... & Huang, S. (2025). Correction: Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2. Oncotarget, 16, 425.
2. Omolekan, T. O., Chamcheu, J. C., Buerger, C., & Huang, S. (2024). PI3K/AKT/mTOR signaling network in human health and diseases. Cells, 13(17), 1500.
3. Mao, Z., Mu, J., Gao, Z., Huang, S., & Chen, L. (2024). Biological functions and potential therapeutic significance of O-GlcNAcylation in hepatic cellular stress and liver diseases. Cells, 13(10), 805.
4. He, H., Cai, T., Chen, Q., Chen, Z., Zhang, B., Chen, C., ... & Guo, X. (2024). TRIM44 promotes rabies virus replication by autophagy-dependent mechanism. International Journal of Molecular Sciences, 25(9), 4616.
5. Li, X., Wu, Y., Yan, Z., Li, G., Luo, J., Huang, S., & Guo, X. (2024). A comprehensive view on the protein functions of porcine epidemic diarrhea virus. Genes, 15(2), 165.
6. Li, S., Xu, B., Luo, Y., Luo, J., Huang, S., & Guo, X. (2024). Autophagy and apoptosis in rabies virus replication. Cells, 13(2), 183.
7. Chen, B., Guo, G., Wang, G., Zhu, Q., Wang, L., Shi, W., ... & Chen, J. L. (2024). ATG7/GAPLINC/IRF3 axis plays a critical role in regulating pathogenesis of influenza A virus. Plos Pathogens, 20(1), e1011958.
8. Zhang, B., Cai, T., He, H., Huang, X., Luo, Y., Huang, S., ... & Guo, X. (2023). TRIM25 suppresses rabies virus fixed HEP-flury strain production by activating RIG-1-mediated type I interferons. Genes, 14(8), 1555.
9. Liu, S., Liu, S., Yu, Z., Zhou, W., Zheng, M., Gu, R., ... & Chen, J. L. (2023). STAT3 regulates antiviral immunity by suppressing excessive interferon signaling. Cell Reports, 42(7).
10. Zhang, B., Cai, T., He, H., Huang, X., Chen, G., Lai, Y., ... & Guo, X. (2023). TRIM21 Promotes Rabies Virus Production by Degrading IRF7 through Ubiquitination. International Journal of Molecular Sciences, 24(13), 10892.
11. Roy, T., Boateng, S. T., Uddin, M. B., Banang-Mbeumi, S., Yadav, R. K., Bock, C. R., ... & Chamcheu, J. C. (2023). The PI3K-Akt-mTOR and associated signaling pathways as molecular drivers of immune-mediated inflammatory skin diseases: update on therapeutic strategy using natural and synthetic compounds. Cells, 12(12), 1671.
12. Yu, Q., Zhang, R., Li, T., Yang, L., Zhou, Z., Hou, L., ... & Chen, L. (2023). Mitochondrial hydrogen peroxide activates PTEN and inactivates Akt leading to autophagy inhibition-dependent cell death in neuronal models of Parkinson’s disease. Molecular neurobiology, 60(6), 3345-3364.
13. Lairmore, T. C., Abdulsattar, J., De Benedetti, A., Shi, R., Huang, S., Khalil, M. I., & Witt, S. N. (2023). Loss of tumor suppressor menin expression in high grade cholangiocarcinomas. BMC Research Notes, 16(1), 15.
14. Roy, T., Banang-Mbeumi, S., Boateng, S. T., Ruiz, E. M., Chamcheu, R. C. N., Kang, L., ... & Chamcheu, J. C. (2023). Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation. Frontiers in immunology, 13, 1075804.
15. Rai, K. R., Liao, Y., Cai, M., Qiu, H., Wen, F., Peng, M., ... & Chen, J. L. (2022). MIR155HG plays a bivalent role in regulating innate antiviral immunity by encoding long noncoding RNA-155 and microRNA-155-5p. Mbio, 13(6), e02510-22.
16. Liu, C., Zhang, R., Yang, L., Ji, T., Zhu, C., Liu, B., ... & Chen, L. (2022). Neuroprotection of resveratrol against cadmium-poisoning acts through dual inhibition of mTORC1/2 signaling. Neuropharmacology, 219, 109236.
17. Yao, Y., Zhu, J., Qin, S., Zhou, Z., Zeng, Q., Long, R., ... & Chen, L. (2022). Resveratrol induces autophagy impeding BAFF-stimulated B-cell proliferation and survival by inhibiting the Akt/mTOR pathway. Biochemical pharmacology, 202, 115139.

Profile Details

WoS ResearcherID: I-1632-2019

https://orcid.org/0000-0002-3239-1072

https://www.louisianacancercenter.org/people/shile-huang-phd

https://scholar.google.com/citations?user=SdEK0_QAAAAJ&hl=en

https://www.researchgate.net/profile/Shile-Huang