Biomedical Sciences

University of California, USA

Email:[email protected]

Qualifications

1991  Ph.D., Biochemistry, Dnipropetrovsk National University, Ukraine
1988  B.Sc., Biochemistry, Dnipropetrovsk National University, Ukraine

Publications (Selected)

1. Koury, J., Singh, H., Sutley-Koury, S. N., Fok, D., Qiu, X., Maung, R., ... & Kaul, M. (2025). EphB2-mediated ephrin-B reverse signaling on microglia drives an anti-viral, but inflammatory and neurotoxic response associated with HIV. Journal of Neuroinflammation, 22(1), 1-18.
2. Sutley-Koury, S. N., Taitano-Johnson, C., Kulinich, A. O., Farooq, N., Wagner, V. A., Robles, M., ... & Ethell, I. M. (2024). EphB2 signaling is implicated in astrocyte-mediated parvalbumin inhibitory synapse development. Journal of Neuroscience, 44(45).
3. Sutley-Koury, S. N., Anderson, A., Taitano-Johnson, C., Ajayi, M., Kulinich, A. O., Contreras, K., ... & Ethell, I. M. (2024). Astrocytic Ephrin-B1 Regulates Oligodendrocyte Development and Myelination. ASN neuro, 16(1), 2401753.
4. Talvio, K., Wagner, V. A., Minkeviciene, R., Kirkwood, J. S., Kulinich, A. O., Umemori, J., ... & Castrén, M. L. (2023). An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. Communications Biology, 6(1), 789.
5. Villa, P. A., Lainez, N. M., Jonak, C. R., Berlin, S. C., Ethell, I. M., & Coss, D. (2023). Altered GnRH neuron and ovarian innervation characterize reproductive dysfunction linked to the fragile X messenger ribonucleoprotein (Fmr1) gene mutation. Frontiers in Endocrinology, 14, 1129534.
6. Dennys, C., Baggio, C., Rodrigo, R., Roussel, F., Kulinich, A., Heintzman, S., ... & Meyer, K. C. (2022). EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis-astrocytes. Iscience, 25(9).
7. Rais, M., Lovelace, J. W., Shuai, X. S., Woodard, W., Bishay, S., Estrada, L., ... & Ethell, I. M. (2022). Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome. Neurobiology of disease, 162, 105577.
8. Contractor, A., Ethell, I. M., & Portera-Cailliau, C. (2021). Cortical interneurons in autism. Nature neuroscience, 24(12), 1648-1659.
9. Pirbhoy, P. S., Jonak, C. R., Syed, R., Argueta, D. A., Perez, P. A., Wiley, M. B., ... & Binder, D. K. (2021). Increased 2-arachidonoyl-sn-glycerol levels normalize cortical responses to sound and improve behaviors in Fmr1 KO mice. Journal of Neurodevelopmental Disorders, 13(1), 47.
10. Peteri, U. K., Pitkonen, J., de Toma, I., Nieminen, O., Utami, K. H., Strandin, T. M., ... & Castrén, M. L. (2021). Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome. Glia, 69(12), 2947-2962.
11. Razak, K. A., Binder, D. K., & Ethell, I. M. (2021). Neural correlates of auditory hypersensitivity in fragile X syndrome. Frontiers in Psychiatry, 12, 720752.
12. Baggio, C., Kulinich, A., Dennys, C. N., Rodrigo, R., Meyer, K., Ethell, I., & Pellecchia, M. (2021). NMR-guided design of potent and selective EphA4 agonistic ligands. Journal of medicinal chemistry, 64(15), 11229-11246.
13. Pirbhoy, P. S., Rais, M., Lovelace, J. W., Woodard, W., Razak, K. A., Binder, D. K., & Ethell, I. M. (2020). Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice. Journal of neurochemistry, 155(5), 538-558.
14. Nguyen, A. Q., Sutley, S., Koeppen, J., Mina, K., Woodruff, S., Hanna, S., ... & Ethell, I. M. (2020). Astrocytic ephrin-B1 controls excitatory-inhibitory balance in developing hippocampus. Journal of Neuroscience, 40(36), 6854-6871.
15. Lovelace, J. W., Ethell, I. M., Binder, D. K., & Razak, K. A. (2020). Minocycline treatment reverses sound evoked EEG abnormalities in a mouse model of fragile X syndrome. Frontiers in neuroscience, 14, 771.

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