Prof. Yunfeng Zhao

Department of Pharmacology, Toxicology & Neuroscience

LSU Health Sciences Center, Shreveport, Louisiana, USA

Associate Professor

Email: [email protected]

Qualifications

2000 Postdoc, University of Kentucky, USA

1997 Ph.D., Jilin University, China

1994 M.S., Jilin University, China

1991 B.S., Jilin University, China

Publications (Selected)

1. Yu J, Shi L, Lin W, Lu B, Zhao Y. UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer. Biochem Pharmacol. 2020;172:113745.

2. Li J, Jia Y, An L, Niu C, Cong X, Zhao Y. Uncoupling protein 2 is upregulated in melanoma cells and contributes to the activation of Akt/mTOR and ERK signaling. Int J Oncol. 2020 Mar 12.
3. Li J, Jiang R, Cong X, Zhao Y. The role of UCP2 gene polymorphisms in obesity and diabetes and the role of UCP2 in cancer. FEBS Lett. 2019; 593:2525-2534.
4. Yu, J, Shi L, Shen X, Zhao, Y. UCP2 regulates cholangiocarcinoma cell plasticity via mitochondria-to-AMPK signals. Biochem Pharmacol. 166:174-184, 2019.
5. Sreedhar A, Cassel T, Smith P, Lu D, Hyung NW, Lane AN, Zhao Y. UCP2 overexpression redirects glucose into anabolic metabolic pathways. Proteomics, 2018; 19:e1800353.
6. Sreedhar A, Li J, Zhao Y. Next-Gen therapeutics for Skin Cancer: Nutraceuticals. Nutrition & Cancer, 2018; 70:697-709.
7. Sreedhar A, Petruska P, Miriyala S, Panchatcharam M, Zhao Y. UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation. Oncotarget. 2017;8:95504-95515.
8. Sreedhar A, Lefort J, Petruska P, Gu X, Shi R, Miriyala S, Panchatcharam M, Zhao Y. UCP2 Upregulation Promotes PLCγ-1 Signaling During Skin Cell Transformation. Mol Carcinog. 2017;56:2290-2300.
9. Sreedhar A, Zhao Y. Uncoupling protein 2 and metabolic diseases. Mitochondrion. 2017;34:135-140. Review.
10. Li W, Zhang C, Du H, Huang V, Sun B, Harris JP, Richardson Q, Shen X, Jin R, Li G, Kevil CG, Gu X, Shi R, Zhao Y. Withaferin A suppresses the up-regulation of acetyl-coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model. Mol Carcinog. 2016;55:1739-1746.
11. Li W, Zhang C, Ren A, Li T, Jin R, Li G, Gu X, Shi R, Zhao Y. Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation. PLoS One. 2015;10:e0126459.
12. Li W, Zhang C, Jackson K, Shen X, Jin R, Li G, Kevil CG, Gu X, Shi R, Zhao Y. UCP2 knockout suppresses mouse skin carcinogenesis. Cancer Prev Res 2015 Jun;8(6):487-91.

Personal Details

https://schoolofgradstudies.lsuhs.edu/academics/pharmacology-toxicology-and-neuroscience/research/zhao-lab

https://www.researchgate.net/profile/Yunfeng-Zhao-2