Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education

School of Chemical Science and Technology, Yunnan University, China

Email: [email protected]

Qualifications

2007 – Present Professor, Yunnan University, China
2006 – 2007  Postdoctoral fellows, Hong Kong Polytechnic University, China
2004 – 2006  Postdoctoral associates, University of Montreal, Canada
2001 – 2004  Ph.D. Lanzhou University, China

1. He, D.; Xu, H.; Cao, P.; Li, L.; Luo, Y.; Mon, E. E.; Peng, F.; Li, L.; Dang, Y.; Shao, Z. Development of Chiral Bisphosphine Ligands with a Terminal Olefin Enables Asymmetric Orthogonal Auto‐Tandem Catalysis Angew. Chem. Int. Ed. 2025, 64, e202506881.
2. Luo, P.; Li, J.; Deng, Y.; Yu, P.; Wang, Y.; Peng, F.; Shao, Z. Angew. Switchable Chemo-, Regio- and Pseudo-Stereodivergence in Palladium-Catalyzed Cycloaddition of Allenes Chem. Int. Ed. 2024, 63, e202412179.
3. Ren, J.; Sun, Z.; Zhao, S.; Huang, J.; Wang, Y. Nat. Enantioselective synthesis of chiral α,α-dialkyl indoles and related azoles by cobalt-catalyzed hydroalkylation and regioselectivity switch Commun. 2024, 15, 3783.
4. Zha, T.; Rui, J.; Zhang, Z.; Zhang, D.; Yang, Z.; Yu, P.; Wang, Y.; Peng, F.; Shao, Z. Angew. Direct Catalytic Asymmetric and Regiodivergent N1- and C3-Allenylic Alkylation of Indoles. Chem. Int. Ed. 2023, 62, e202300844.
5. Dai, J.; Li, L.; Ye, R.; Wang, S.; Wang, Y.; Peng, F.; Shao, Z. Angew. Construction of Acyclic All-Carbon Quaternary Stereocenters and 1,3-Nonadjacent Stereoelements via Organo/Metal Dual Catalyzed Asymmetric Allenylic Substitution of Aldehydes. Chem. Int. Ed. 2023, 62, e202300756.
6. Li, L.; Wang, S.; Luo, P.; Wang, R.; Wang, Z.; Li, X.; Deng, Y.; Peng, F.; Shao, Z. Direct access to spirocycles by Pd/WingPhos-catalyzed enantioselective cycloaddition of 1,3-enynes Nat. Commun. 2021, 12, 5667.
7. Yang, B.; Dai, J.; Luo, Y.; Lau, K.; Lan, Y.; Shao, Z.; Zhao, Y. Desymmetrization of 1,3-Diones by Catalytic Enantioselective Condensation with Hydrazine. J. Am. Chem. Soc. 2021, 143, 4179.
8. Yang , L.; Wang , Y.; Liu, R.; Luo , Y.; Ng , X. Q.; Yang, B.; Rong, Z.; Lan , Y.; Shao , Z.; Zhao, Y. Stereoselective access to [5.5.0] and [4.4.1] bicyclic compounds through Pd-catalysed divergent higher-order cycloadditions. Nat. Chem. 2020, 12, 860.
9. Dai, J.; Wang, Z.; Deng, Y.; Zhu, L.; Peng, F.; Lan, Y.; Shao, Z. Nat. Commun. 2019, 10, 5182.
10. Li, L.; Luo, P.; Deng, Y.; Shao, Z. Angew. Regioselectivity Switch in Palladium-Catalyzed Allenylic Cycloadditions of Allenic Esters: [4+1] or [4+3] Cycloaddition/Cross-Coupling. Chem. Int. Ed. 2019, 58, 4710.
11. Shao, Z.-H.;* Zhang, H.-B. Combining of transition metal catalysis and organocatalysis: a broad new concept for catalysis  Chem. Soc. Rev. 2009, 38, 2745-2755
12. Shao, Z.-H.;* Zhang, H.-B. N-Tosylhydrazones: versatile reagents for metal-catalyzed and metal-free cross-coupling reactions  Chem. Soc. Rev. 2012, 41, 560-572
13. Shao, Z.-H.;* Peng, F.-Z. Metal-mediated oxidative cross-coupling of terminal alkynes: a promising strategy for alkyne synthesis Angew.  Chem. Int. Ed. 2010, 49, 9566-9568
14. Li, Y.-M.; Li, X.; Peng, F.-Z.; Li, Z.-Q.; Wu, S.-T.; Sun, Z.-W.; Zhang, H.-B.; Shao, Z.-H.* Catalytic asymmetric construction of spirocyclopentaneoxindoles by a combined Ru-catalyzed cross-metathesis/double Michael addition sequence Org. Lett. 2011, 13, 6200-6203
15. Li, X.; Li, Y.-M.; Peng, F.-Z.; Wu, S.-T.; Li, Z.-Q.; Sun, Z.-W.; Zhang, H.-B.; Shao, Z.-H.* Highly enantioselective one-pot synthesis of spirocyclopentaneoxindoles containing the oxime group by organocatalyzed Michael addition/ISOC/fragmentation sequence. Org. Lett. 2011, 13, 6160-6163
16. Fan, B.-M.; Li, X.-J.; Peng, F.-Z.; Zhang, H.-B.; Chan, A. S. C.; Shao, Z.-H.* Ligand-controlled enantioselective [2 + 2] cycloaddition of oxabicyclic alkenes with terminal alkynes using chiral iridium catalysts Org. Lett. 2010, 12, 304-306
17. Peng, F.-Z.; Shao, Z.-H.;* Pu, X.-W.; Zhang, H.-B. Highly diastereo- and enantioselective direct aldol reactions promoted by water-compatible organocatalysts bearing central and axial chiral elements Adv. Synth. Catal. 2008, 350, 2199-2204
18. Li, X.; Li, X.-J.; Peng, F.-Z.; Shao, Z.-H.* Mutually complementary metal- and organocatalysis with collective synthesis: asymmetric conjugate addition of 1,3-carbonyl compounds to nitroenynes and further reactions of the products Adv. Synth. Catal. 2012, 354, DOI: 10.1002/adsc.201200226
19. Li, X.-J.; Peng, F.-Z.; Li, X.; Wu, W.-T.; Sun, Z.-W.; Li, Y.-M.; Zhang, S.-X.; Shao, Z.-H.* Enantio- and regioselective organocatalytic conjugate addition of malonates to nitroenynes Chem. Asian J. 2011, 6, 220-225
20. Sun, Z.-W.; Peng F.-Z.; Li, Z.-Q.; Zou, L.-W.; Zhang, S.-X.; Li, X.; Shao, Z.-H.* Enantioselective conjugate addition of both aromatic ketones and acetone to nitroolefins catalyzed by chiral primary amines bearing multiple hydrogen-bonding donors. J. Org. Chem. 2012, 77, 4103