Dr. Darren Michael Riehl Brenner

Cumming School of Medicine
University of Calgary, Canada

Email: [email protected]

Qualifications

2008 Ph.D., University of Toronto, Epidemiology

2006 M.Sc., Brock University, Applied Health Science

2002 B.Sc., Brock University, Health Science

Publications (selected)

1. Bales, C., Kang, A. J., Moy, B. M., et al. (2026). LIMITED ASSOCIATION BETWEEN PATIENT-REPORTED OUTCOME MEASURES AND PHYSIOLOGIC MEASUREMENTS DURING ANORECTAL MANOMETRY AND BALLOON EXPULSION TESTING. Gastroenterology, 170(6, Suppl. S), S1808–S1809.
2. Brenner, D. R., Feng, X. H., Maxwell, C., et al. (2026). The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) - Cohort Description. Cancer Control, 33, Article 10732748251413334.
3. Georgeson, P., Prisc, A., Joo, J. E., et al. (2025). Mutational signature profiling identifies a distinct subgroup of early-onset colorectal cancer associated with younger age at diagnosis, recent birth year and specific genomic features. Clinical Cancer Research, 31(23, Suppl. S), PR4.
4. Georgeson, P., Prisc, A., Joo, J., et al. (2025). Novel insights from the investigation of experimental mutational signatures in early-onset colorectal cancer and colonic polyps. Clinical Cancer Research, 31(23, Suppl. S).
5. Prisc, A., Georgeson, P., Joo, J. E., et al. (2025). Unexplained familial early-onset colorectal cancer: Determining a shared etiology by tumor mutational signature profiling. Clinical Cancer Research, 31(23, Suppl. S).
6. Lemelin, A., Maj, D., Takemura, K., et al. (2025). CABOSEQ 3-Comparison of Cabozantinib versus Sunitinib Following First-Line Nivolumab-Ipilimumab for Metastatic Renal Cell Carcinoma: A Target Trial Emulation Using Real-World Data from the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC). Clinical Genitourinary Cancer, 23(6), Article 102431.
7. Griffin, D., MacDonald, I. E., Danforth, J. M., et al. (2025). Economic Burden of Radon Attributable Non-Small Cell Lung Cancer: A Cost Analysis. Journal of Thoracic Oncology, 20(10, Suppl. 1), P3.01.24.
8. Brenner, D. R., Ruan, Y. B., & Carbonell, C. (2025). Potential Impact of Next-Generation Weight Loss Drugs on Cancer Incidence. JAMA Network Open, 8(9), Article e2530904.
9. Brenner, D. M., Raju, K., Kozuka, K., et al. (2025). NEITHER TENAPANOR NOR ITS MAJOR METABOLITE WERE DETECTED IN THE BREAST MILK OF HEALTHY LACTATING FEMALES AFTER 4 DAYS OF DOSING: A PHASE 1, OPEN-LABEL, PHARMACOKINETIC STUDY. Gastroenterology, 169(1, Suppl. S), Sa1673.
10. Brenner, D. M., Rao, S. S., Curtin, B. F., et al. (2025). LONG-TERM, REAL-WORLD EXPERIENCE OF VIBRATING CAPSULE TREATMENT FOR PATIENTS WITH CHRONIC IDIOPATHIC CONSTIPATION. Gastroenterology, 169(1, Suppl. S), Sa1677.
11. Brenner, D. R., Feng, X. H., Maxwell, C., et al. (2025). THE COLORECTAL CANCER CHEMOPREVENTION ACCELERATION AND IMPROVEMENT PLATFORM (CRC-CHAMP)-COHORT DESCRIPTION. Gastroenterology, 169(1, Suppl. S), Tu1760.
12. Leite, G., Rezaie, A., Mathur, R., et al. (2025). LACTULOSE BREATH TESTING IS MORE OFTEN POSITIVE AND ASSOCIATED WITH SYMPTOMS COMPARED TO GLUCOSE IN A NATIONWIDE STUDY OF KIT-BASED THREE-GAS BREATHING. Gastroenterology, 169(1, Suppl. S), Tu2015.
13. Lembo, A., Quigley, E. M., Rao, S. S., et al. (2025). DIURINAL DISTRIBUTION OF CSBMS (COMPLETE SPONTANEOUS BOWEL MOVEMENT) IN CHRONIC IDIOPATHIC CONSTIPATION (CIC) PATIENTS TREATED WITH A VIBRATING CAPSULE. Gastroenterology, 169(1, Suppl. S), Sa1686.
14. Ma, C., Ford, A. C., Hashash, J. G., et al. (2025). JOINT IOIBD-ROME CONSENSUS RECOMMENDATIONS FOR THE EVALUATION AND MANAGEMENT OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE WITH IRRITABLE BOWEL SYNDROME-LIKE SYMPTOMS. Gastroenterology, 169(1, Suppl. S), Mo1248.
15. Rezaie, A., Leite, G., Mathur, R., et al. (2025). REAL WORLD STUDY OF THREE-GAS BREATH TESTING NATIONWIDE AND THE ASSOCIATION WITH SYMPTOMS. Gastroenterology, 169(1, Suppl. S), Mo1405.
16. Wang, C., Patel, R. H., Yarlagadda, S., et al. (2025). DYSSYNERGIA NORMALIZATION IN THE SEATED POSITION PREDICTS NORMAL BALLOON EXPULSION TESTING ON HIGH-RESOLUTION ANORECTAL MANOMETRY. Gastroenterology, 169(1, Suppl. S), Sa1744.
17. Chang, L., Brenner, D. M., Chen, W., et al. (2024). EFFICACY, SAFETY, AND TIME TO RESPONSE OF LINACLOTIDE IN PATIENTS ≥ 65 WITH IRRITABLE BOWEL SYNDROME WITH CONSTIPATION. Gastroenterology, 166(5, Suppl. S), S1366.
18. Rezaie, A., Leite, G., Mathur, R., et al. (2024). MAIL-IN BREATH TESTING REVEALS THE RELATIONSHIP BETWEEN EXHALED METHANE AND GASTROINTESTINAL SYMPTOMS: A LARGESCALE NATIONWIDE STUDY OF COMMUNITY PRACTICES. Gastroenterology, 166(5, Suppl. S), S785–S786.
19. Shah, E. D., de Courcy, Joanna., Jiang, J., et al. (2024). DIAGNOSTIC JOURNEY OF PATIENTS WITH CHRONIC IDIOPATHIC CONSTIPATION IN THE USA: ANALYSIS FROM A CROSS-SECTIONAL OBSERVATIONAL STUDY. Gastroenterology, 166(5, Suppl. S), S1220–S1221.
20. Brenner, D. M., Poppers, D., Laitman, A. P., et al. (2023). PLECANATIDE IMPROVES ABDOMINAL PAIN, BLOATING, AND STRAINING SYMPTOMS IN ADULTS WITH IRRITABLE BOWEL SYNDROME WITH CONSTIPATION (IBS-C): A NEW COMPOSITE ENDPOINT ANALYSIS OF TWO RANDOMIZED, PHASE 3 TRIALS. Gastroenterology, 164(6, Suppl. S), S1058–S1059.

Profile Details
https://profiles.ucalgary.ca/darren-brenner
https://www.researchgate.net/scientific-contributions/Darren-M-Brenner-2007257858
https://scholar.google.com/citations?user=AmoC5LUAAAAJ&hl=en

WOS ResearcherID：A-9725-2012