Prof. Joseph M. Wallace III

Weldon School of Biomedical Engineering
Purdue University, USA

Email: [email protected]

Qualifications

2007 Ph.D., University of Michigan, USA, Biomedical Engineering

2003 M.Sc., University of Michigan, USA, Biomedical Engineering

2002 B.Sc., Georgia Institute of Technology, USA, Aerospace Engineering

Publications (selected)

1. Miller, C., Segvich, D. M., Wanner, J., et al. (2026). Effects of spermine on osteoblasts during iron deficiency in vitro and in vivo during chronic kidney disease. Bone, 208, Article 117867.
2. Arnhart, M., Surowiec, R. K., Allen, M. R., et al. (2025). A measure of intrinsic strength, not nominal strength, reflects effects of ex-vivo cortical bone matrix modulation by raloxifene. Journal of the Mechanical Behavior of Biomedical Materials, 166, Article 106956.
3. Gallaway, G., Surowiec, R. K., Allen, M. R., et al. (2025). Quasi-brittle fracture mechanics to assess ex vivo Raloxifene treatment of human cortical bone. International Journal of Solids and Structures, 320, Article 113506.
4. Kohler, R., Segvich, D. M., Reul, O., et al. (2025). Combined Romosozumab and Raloxifene treatment targets impaired bone quality in a male murine model of diabetic kidney disease. Bone, 194, Article 117415.
5. Reul, O. N., Surowiec, R. K., Chowdhury, N. N., et al. (2025). Skeletal impacts of dual in vivo compressive axial tibial and ulnar loading in mice. Journal of the Mechanical Behavior of Biomedical Materials, 165, Article 106950.
6. Chowdhury, N. N., Surowiec, R. K., Kohler, R. K., et al. (2024). Metabolic and Skeletal Characterization of the KK/Ay Mouse Model-A Polygenic Mutation Model of Obese Type 2 Diabetes. Calcified Tissue International, 114(6), 638–649.
7. Creecy, A., Segvich, D., Metzger, C., et al. (2024). Combining anabolic loading and raloxifene improves bone quantity and some quality measures in a mouse model of osteogenesis imperfecta. Bone, 184, Article 117106.
8. Kohler, R., Creecy, A., Williams, D. R., et al. (2024). Effects of novel raloxifene analogs alone or in combination with mechanical loading in the Col1a2G610c/+ murine model of osteogenesis imperfecta. Bone, 179, Article 116970.
9. Kuah, A. H., Sattgast, L. H., Grant, K. A., et al. (2024). Six months of voluntary alcohol consumption in male cynomolgus macaques reduces intracortical bone porosity without altering mineralization or mechanical properties. Bone, 185, Article 117111.
10. LaCombe, J. M., Sloan, K., Thomas, J. R., et al. (2024). Sex-specific trisomic Dyrk1a-related skeletal phenotypes during development in a Down syndrome model. Disease Models & Mechanisms, 17(9), Article dmm050914.
11. Lamantia, J., Sloan, K., Wallace, J. M., et al. (2024). Compromised femoral and lumbovertebral bone in the Dp(16)1Yey Down syndrome mouse model. Bone, 181, Article 117046.
12. Ramirez, G., Okpara, C., Arnett, M., et al. (2024). Independent contribution of gonads and sex chromosomes to sex differences in bone mass and strength in the four-core genotypes mouse model. Journal of Bone and Mineral Research, 39(11), 1659–1672.
13. Surowiec, R. K., Reul, O. N., Chowdhury, N. N., et al. (2024). Combining raloxifene and mechanical loading improves bone composition and mechanical properties in a murine model of chronic kidney disease (CKD). Bone, 183, Article 117089.
14. Williams, D. R., Taylor, L., Miter, G. A., et al. (2024). Synthesis Studies and the Evaluation of C6 Raloxifene Derivatives. ACS Medicinal Chemistry Letters, 15(6), 879–884.
15. Balanta-Melo, J., Deosthale, P., Kohler, R., et al. (2023). Impact of sex hormone deficiency in mice expressing the Alzheimer′s disease-associated risk-factor TREM2 R47H variant in a sex and genotype dependent manner. Journal of Bone and Mineral Research, 38(Suppl. 2), 267.
16. Deosthale, P., Balanta-Melo, J., Creecy, A., et al. (2023). Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice. Bone Research, 11(1), Article 25.
17. Jacobson, A., Newman, C., Siegmund, T., et al. (2023). An MRI-based Approach for Characterizing Bone Mineral Density and Cortical Porosity: Comparing Ultrashort Echo Time MRI with HR-pQCT. Journal of Bone and Mineral Research, 38(Suppl. 2), 167.
18. Khairallah, P., Cherasard, J., Sung, J. S., et al. (2023). Changes in Bone Quality after Treatment with Etelcalcetide. Clinical Journal of the American Society of Nephrology, 18(11), 1456–1465.
19. Korff, C., Atkinson, E., Adaway, M., et al. (2023). NMP4, an Arbiter of Bone Cell Secretory Capacity and Regulator of Skeletal Response to PTH Therapy. Calcified Tissue International, 113(1), 110–125.
20. Newman, C. L., Surowiec, R. K., Swallow, E. A., et al. (2023). Assessing cortical bone porosity with MRI in an animal model of chronic kidney disease. Bone, 173, Article 116808.

Profile Details
https://engineering.purdue.edu/BBML/PI.html
https://scholar.google.com/citations?user=hJbuTMUAAAAJ&hl=en
https://www.researchgate.net/profile/Joseph-Wallace-2

WOS ResearcherID: G-7906-2012