Biography

Dr. Xuanyong Lu

Institute of Hepatitis and Virus Research, USA
Associate Professor


Email: [email protected]


Qualifications

1994  Post-Doctor, Institute for Medical Virology of University Giessen

1989  Ph.D., Gottingen University, Virology

1982 bachelor of Science, Nanjing University, Biochemistry


Publications(Selected)

  1. Lamontagne, J., Mills, C., Mao, R.-C. and Lu, X. Screening and identification of compounds with antiviral activity against hepatitis B virus using a safe compound library and novel real-time immune-absorbance PCR-based high throughput system. 2013.
  2. Lu, F., Lamontagne, J., Sun, A. and Lu, X. Role of the inflammatory protein serine protease inhibitor Kazal in preventing cytolytic granule granzyme A-mediated apoptosis. 2011.
  3. Guo, H., Pan, X., Mao, R.-C. and Block, T. Alkylated Porphyrins Have Broad Antiviral Activity against Hepadnaviruses, Flaviviruses, Filoviruses, and Arenaviruses. 2011.
  4. Lu, X. Pathogenesis of Hepatitis B Virus (HBV)-Mediated Liver Injury. 2011.
  5. Lamontagne, J., Pinkerton, M., Block, T. and Lu, X. Hepatitis B and Hepatitis C Virus Replication Upregulates Serine Protease Inhibitor Kazal, Resulting in Cellular Resistance to Serine Protease-Dependent Apoptosis. 2010.
  6. Lu, X., Lamontagne, J., Lu, F. and Block, T. Tumor-associated protein SPIK/TATI suppresses serine protease dependent cell apoptosis. 2008.
  7. Şimşek, E., Lu, X., Ouzounov, S. and Mehta, A.S. α-Glucosidase Inhibitors Have a Prolonged Antiviral Effect against Hepatitis B Virus through the Sustained Inhibition of the Large and Middle Envelope Glycoproteins. 2006.
  8. Huang, T.-J., Lu, C.-C., Tsai, J.-C. and Shiau, A.-L. Novel Autoregulatory Function of Hepatitis B Virus M Protein on Surface Gene Expression. 2005.
  9. Lu, X. and Hu, K.-Q. Advances in Hepatitis B Research: From Virology to Clinical Management (A Special Issue). 2005.
  10. Lu, X., Lee, M., Tran, T. and Block, T. High level expression of apoptosis inhibitor in hepatoma cell line expressing Hepatitis B virus. 2005.
  11. Lu, X., Weiss, P. and Block, T. A phage with high affinity for hepatitis B surface antigen for the detection of HBsAg. 2004.
  12. Lu, X. and Block, T. Study of the early steps of the Hepatitis B Virus life cycle. 2004.
  13. Lu, X. and Block, T. Enhancement of Infection of HepG2 Cells in Culture by Predigestion of Hepadnavirus with V8 Protease. 2004.
  14. Lu, X., Tran, T., Şimşek, E. and Block, T. The Alkylated Imino Sugar, n-(n-Nonyl)-Deoxygalactonojirimycin, Reduces the Amount of Hepatitis B Virus Nucleocapsid in Tissue Culture. 2003.
  15. Norton, P.A., Gong, Q., Mehta, A.S. and Block, T. Hepatitis B Virus-Mediated Changes of Apolipoprotein mRNA Abundance in Cultured Hepatoma Cells. 2003.
  16. Mehta, A., Ouzounov, S., Jordan, R. and Block, T. Imino Sugars That are Less Toxic but More Potent as Antivirals, In Vitro, Compared with N-n-Nonyl DNJ. 2002.
  17. Lu, X., Tran, T., Simsek, E. and Block, T. Secretion of human hepatitis B virus is inhibited by the imino sugar N -butyldeoxynojirimycin (antivirals/glycosylation). 2000.


Personal Details

https://www.researchgate.net/profile/Xuanyong-Lu

WoS Researcher ID: KJH-8148-2024

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