Prof. Guanghui Liu

Chinese Academy of Sciences, Institute of Biophysics, China

Email: [email protected]

Qualifications

2007 Ph.D., Graduate University of Chinese Academy of Sciences, China

2002 B.S., Peking University Health Science Center, China

Publications (Selected)

1. Jiang, M., Qu, J., Song, M., et al. (2026). Intervening in aging and related diseases with gene therapy techniques. Cell Reports Medicine, 7(7), Article 102870.
2. Chu, Q., Li, Y., Wu, Z., et al. (2026). Mechanisms and interventions of epigenetic aging. Cell Chemical Biology, 33(6), 748–766.
3. Li, J., Lu, X., Tong, T., et al. (2026). Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin. Nature Aging, 6(6).
4. Sun, S., Li, J., Wang, S., et al. (2026). CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord. Nature, 654(8119), E19.
5. Li, M., Jiang, X., Jing, Y., et al. (2026). CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells. Protein & Cell, 17(6).
6. Lu, J. Y., Tu, W. B., Ma, S., et al. (2026). Mesenchymal drift: A convergent framework for the hallmarks of aging. Cell, 189(11), 3184–3213.
7. Lu, H., Cai, L., Lv, D., et al. (2026). Restoring the FOXO1 geroprotective pathway via seno-resistant mesenchymal progenitor cells alleviates primate epididymal aging. Protein & Cell.
8. Jing, Y., Ma, S., & Liu, G. (2026). Multimorbidity defines glycaemic individuality in ageing. Nature Metabolism, 8(5), 1016–1018.
9. Ping, J., Qiao, Q., Gao, D., et al. (2026). Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence. Immunity, 59(4), 1039–1037.
10. Liu, L., Zheng, Z., You, W., et al. (2026). Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates. Cell Metabolism, 38(4), 673–693.
11. Sun, X., Che, S., Wang, H., et al. (2026). Vascular organoid model of Hutchinson-Gilford progeria syndrome uncovers repression of the SRF pathway in premature aging. Developmental Cell, 61(3), 505–517.
12. Sun, G., He, Z., Lv, D., et al. (2026). Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging. Nature Aging, 6(1).
13. Wang, Z., Ji, Q., Liu, Z., et al. (2025). Nuclear-lamin-guided plastic positioning and folding of the human genome. Cell Reports, 44(11), Article 116529.
14. Zheng, Y., Liu, C., Zhang, W., et al. (2025). scITDG: a tool for identifying time-dependent genes in single-cell transcriptome sequencing data. Marine Life Science & Technology, 7(4), 792–807.
15. Ding, Y., Zuo, Y., Zhang, B., et al. (2025). Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures. Cell, 188(20), 5763–5784.
16. Liu, G., & Wang, S. (2025). Molecular marker of cochlear aging and hearing loss in primates. Nature Aging, 5(10), 1944–1945.
17. Geng, L., Ping, J., Wu, R., et al. (2025). Systematic profiling reveals betaine as an exercise mimetic for geroprotection. Cell, 188(19), 5426–5428.
18. Geng, L., Ping, J., Wu, R., et al. (2025). Systematic profiling reveals betaine as an exercise mimetic for geroprotection. Cell, 188(19).
19. Wu, Z., Qu, J., Zhang, W., et al. (2025). Biomarkers of ageing of humans and non-human primates. Nature Reviews Molecular Cell Biology, 26(11), 826–847.
20. Lei, J., Xin, Z., Liu, N., et al. (2025). Senescence-resistant human mesenchymal progenitor cells counter aging in primates. Cell, 188(18), 5039–5061.

Profile Details
http://english.ioz.cas.cn/sourcedb/scs/202512/t20251225_1142399.html
https://people.ucas.ac.cn/~guanghuiliu?language=en
https://www.researchgate.net/profile/Guang-Hui-Liu

WOS ResearcherID: JSV-5748-2023