Dr. Kalin Yanbo Zhang

School of Chinese Medicine

The University of Hong Kong, China

Pharmacologist and Associate Professor

Email: [email protected]

Qualifications:

2001-2003 Ph.D., Depart. of Biochemistry, The Chinese University of Hong Kong, China

1998-2000 M.Sc., Depart. of Biology, Hong Kong Baptist University, China

1978-1982 B.Sc., Chinese Pharmacy, Liaoning University of Chinese Medicine, China

Publications(Selected)

1. Chen, Xiao-Xin & Khyeam, Sheamin & Zhang, Zhang-Jin & Zhang, Kalin. (2022). Granatin B and punicalagin from Chinese herbal medicine pomegranate peels elicit reactive oxygen species-mediated apoptosis and cell cycle arrest in colorectal cancer cells. Phytomedicine. 97. 153923. 10.1016/j.phymed.2022.153923. 
2. Wan, Jack & Lam, Kar-Ho & Song, Michael Tianhe & Lin, Xiang & Leung, Leanne Lee & Fong, Tung-Leong & Lau, Ngai & Wong, Chi-Ho & Huang, Ying-Yi & Leung, George & Shi, Yi-Gang & Lee, Kai-Fai & Wan, Hung & Ng, Tzi & Wang, Jian-Feng & Zhang, Zhang-Jin & Zhang, Kalin & Tang, Sydney. (2021). Review of the therapeutic effects of the traditional Chinese medicine yuye decoction on diabetes mellitus and its complications. Journal of Translational Science. 7. 10.15761/JTS.1000395. 
3. Zhang, Kalin & Lee, Kai-Fai & Leung, George & Chen, Haiyong & Wan, Hei & Su, Jing & Lam, Kar-Ho & Tian, Ling-Min & Tian, Min-Yi & Tse, Sonny & Tang, Sydney & Meng, Wei & Lin, Xiang & Chen, Xiao-Xin & Feng, Yi-Bin & Zhang, Zhang-Jin. (2020). Evidence for Edible Chinese Herbal Medicine as an Alternative Approach for the Treatment of Colorectal Cancer. Clinical Oncology and Research. 1-9. 10.31487/j.COR.2020.06.08. 
4. Cheng, Issac & Li, Ren‐Kai & Leung, George & Li, Song-Lin & Kong, Ming & Lao, Li‐Xing & Zhang, Zhang-Jin & Lin, Wai‐Ling & Ng, Ernest & Rong, Jianhui & Chen, Jian‐Ping & Su, Jing & Zhang, Kalin & Meng, Wei. (2019). Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment. Phytochemical Analysis. 30. 10.1002/pca.2827. 
5. Chen, Xiao-Xin & Lam, Kar & Chen, Qing-Xi & Leung, George & Tang, Sydney & Sze, Stephen Cho Wing & Xiao, Jianbo & Feng, Feng & Wang, Ying & Zhang, Kalin & Zhang, Zhang-Jin. (2017). Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats. Food and Chemical Toxicology. 110. 10.1016/j.fct.2017.10.017. 
6. Chen, Xiao-Xin & Leung, George & Zhang, Zhang-Jin & Xiao, Jianbo & Lao, Li-Xing & Feng, Feng & Mak, Judith & Wang, Ying & Sze, Stephen Cho Wing & Zhang, Kalin. (2017). Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil. Food and Chemical Toxicology. 107. 10.1016/j.fct.2017.07.012. 
7. Liu, Jing-Yi & Chen, Xiao-Xin & Tang, Sydney & Sze, Stephen Cho Wing & Feng, Yibin & Lee, Kai-Fai & Zhang, Kalin. (2016). Chinese medicines in the treatment of experimental diabetic nephropathy. Chinese Medicine. 11. 10.1186/s13020-016-0075-z. 
8. Lin X, Liu JY, Chung WY, Stephen Sze CW, Li HY, Lao LX, Zhang YB. Polysaccharides of Dendrobium officinale Induce AQP-5 Translocation by Activating M3 Muscarinic Receptor. Planta Med 2 (81): 130-137 2015.
9. Lam Y, Ng TB, Yao RM, Shi J, Xu K, Sze SCW, Zhang YB. Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants. EVID-BASED COMPL ALT Volume 2015, Article ID 841752, 25 pages.
10. Song TH, Yang H, James Man Ho CM, Tang SCW, Sze SCW, Lao LX, Wang Y,Zhang KYB. Expression of aquaporin 5 (AQP5) in primary carcinoma and lymph node metastatic carcinoma of non-small cell lung cancer. ONCOL LETT 9: 2799-804 2015.
11. Song TH, Zhang KYB. Enhanced antitumor effect of dendrobine combined with cisplatin for treating non-small cell lung cancer. ONCOL LETT. 9: 2799, 2015; and Proceedings of the Conference in Translation of the Cancer Genome. American Organization by American Association for Cancer Research, San Francisco, California. Paper and poster presentation.
12. Liu JY. Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB. Experiment study on the intestinal absorption of lignans from Fructus Schisandra Chinensis. ELECTROPHORESIS 35: 2907, 2014; and Proceedings of The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research, Hong Kong, China. Paper and poster presentation.
13. Song TH, Zhang KYB, Lao LX, Lee KF, Sydney Tang CW, Ng TB, Stephen Sze CW. Simultaneous determination of berberine and palmatine in human plasma and urine by capillary electrophoresis combined with polypropylene hollow fiber liquid-liquid-liquid microextraction.Anal Methods 6: 7928-7934 2014.
14. Jingyi LIU, Sydney Chi Wai Tang, Stephen Cho Wing Sze, Lixing Lao, James Chung Man Ho, Calvin Kai Fai Lee, Yanbo ZHANG. Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15-16/11/2014, Hong Kong.
15. Chan YS,Zhang YB,SzeCW,Ng TB. A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans.J Enzyme Inhib Med ChemAug; 29(4): 485-490 2014.
16. Li P, Zhang ZM, Li T, Zhang YB, Sze SC, Wang GC, Li YL, Ye WC. Monoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity. Fitoterapia 98C:124-129 2014.
17. Fan J, Guan L, Kou Z, Feng F, Zhang YB, Liu WY. Determination of chrysotoxine in rat plasma by liquid chromatography-tandem mass spectrometry and its application to a rat pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 967: 57-62 2014.
18. Liu JY, Nickolaj Jacob Petersen, Lee KF, Lao LX, Steen Honoré Hansen, Sze CW, Zhang YB. Application of Temperature-Correlated Mobility Theory for Optimizing the MEKC Separation of the Main Lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction. ELECTROPHORESIS 35: 2907-2914. 2014.
19. Chan YS, Zhang YB, Ng TB. Brown kidney bean Bowman-Birk trypsin inhibitor is highly thermostable and pH-stable and exhibits antiproliferative activity on breast cancer cells. J SCI FOOD AGR 169(4): 1306-1314 2013.
20. X Lin,Stephen Sze CW,Ng TB,Tong Y,Shaw PC,Tang SCW,Kalin Zhang KYB. Polysaccharides of Dendrobium officinale inhibit TNF-α-induced apoptosis in A-253 cell line.Inflamm Res2013 Mar; 62(3): 313-24.

Profile Details

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