Prof. Mirko Diksic

Department of Neurology and Neurosurgery

McGill University, Canada

Email: [email protected]

Qualifications

1970  Ph.D., University of Zagreb, Zagreb, Croatia

1968  M.Sc., University of Zagreb, Zagreb, Croatia

1966  B.Sc., University of Zagreb, Croatia

Publications (selected)

1. Diksic, Mirko & Reba, Richard. (2021). Radiopharmaceuticals and Brain Pathology Studied with PET and SPECT. 10.4324/9780429278983. 
2. Lissemore, Jennifer & Sookman, Debbie & Gravel, Paul & Berney, Alexandre & Barsoum, Amir & Diksic, Mirko & Nordahl, Thomas & Pinard, Gilbert & Sibon, Igor & Cottraux, Jean & Leyton, Marco & Benkelfat, Chawki. (2018). Brain serotonin synthesis capacity in obsessive-compulsive disorder: Effects of cognitive behavioral therapy and sertraline. Translational Psychiatry. 8. 82. 10.1038/s41398-018-0128-4. 
3. Booij, Linda & Welfeld, Krzysztof & Leyton, Marco & Dagher, Alain & Boileau, Isabelle & Sibon, Igor & Baker, Glen & Diksic, Mirko & Soucy, J-P & Pruessner, J & Cawley-Fiset, E & Casey, K & Benkelfat, Chawki. (2016). Dopamine cross-sensitization between psychostimulant drugs and stress in healthy male volunteers. Translational Psychiatry. 6. e740. 10.1038/tp.2016.6. 
4. Diksic, Mirko & Swoboda, Victor. (2015). In memoriam: William Feindel, O.C., G.O.Q., MDCM, D. Phil; July 12, 1918—January 12, 2014. Journal of Cerebral Blood Flow & Metabolism. 35. 10.1038/jcbfm.2014.234. 
5. Booij, Linda & Soucy, Jean‐Paul & Young, Simon & Regoli, Martine & Gravel, Paul & Diksic, Mirko & Leyton, Marco & Pihl, Robert & Benkelfat, Chawki. (2014). Brain Serotonin Synthesis in MDMA (Ecstasy) Polydrug Users: An alpha-[11C]Methyl-L-tryptophan Study. Journal of Neurochemistry. 131. 10.1111/jnc.12826. 
6. Sakai, Yojiro & Nishikawa, M & Diksic, Mirko & Aubé, Michel. (2013). -[11C] methyl-L tryptophan-PET as a surrogate for interictal cerebral serotonin synthesis in migraine without aura. Cephalalgia : an international journal of headache. 34. 10.1177/0333102413506126. 
7. Skelin, Ivan & Fikre-Merid, Maraki & Diksic, Mirko. (2012). Both acute and subchronic treatments with pindolol, a 5-HT1A and β1 and β2 adrenoceptor antagonist, elevate regional serotonin synthesis in the rat brain: An autoradiographic study. Neurochemistry international. 61. 10.1016/j.neuint.2012.10.006. 
8. Muck-Šeler, Dorotea & Pivac, Nela & Diksic, Mirko. (2012). Acute treatment with fluvoxamine elevates rat brain serotonin synthesis in some terminal regions: An autoradiographic study. Nuclear medicine and biology. 39. 1053-7. 10.1016/j.nucmedbio.2012.04.001. 
9. Skelin, Ivan & Kovacevic, Tomislav & Sato, Hiroki & Diksic, Mirko. (2012). The opposite effect of a 5-HT1B receptor agonist on 5-HT synthesis, as well as its resistant counterpart, in an animal model of depression. Brain research bulletin. 88. 477-86. 10.1016/j.brainresbull.2012.04.009. 
10. Kovacevic, Tomislav & Skelin, Ivan & Minuzzi, Luciano & Rosa, Pedro & Diksic, Mirko. (2012). Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: An autoradiographic study. Brain research bulletin. 87. 406-12. 10.1016/j.brainresbull.2012.01.010. 
11. Booij, Linda & Benkelfat, Chawki & Leyton, Marco & Vitaro, Frank & Gravel, Paul & Levesque, Melissa & Arseneault, Louise & Diksic, Mirko & Tremblay, Richard. (2012). Perinatal effects on in vivo measures of human brain serotonin synthesis in adulthood: A 27-year longitudinal study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 22. 419-23. 10.1016/j.euroneuro.2011.11.002. 
12. Hasegawa, Shu & Fikre-Merid, Maraki & Diksic, Mirko. (2011). 5-HT2A receptor antagonist M100907 reduces serotonin synthesis: An autoradiographic study. Brain research bulletin. 87. 44-9. 10.1016/j.brainresbull.2011.10.009. 
13. Diksic, Mirko. (2011). Generation of Functional Images of The Brain Trapping Constant for α-[11C]Methyl-L-Tryptophan Using Constrained Linear Regression. The Open Medical Imaging Journal. 5. 14-25. 10.2174/1874347101105010014. 
14. Skelin, Ivan & Kovacevic, Tomislav & Diksic, Mirko. (2011). Neurochemical and Behavioural Changes in Rat Models of Depression. Croatica Chemica Acta. 84. 287-299. 10.5562/cca1817). 
15. Kovacevic, Tomislav & Skelin, Ivan & Diksic, Mirko. (2011). Fluoxetine Treatment has a Larger Effect on the Density of a Serotonin Transporter in the FSL Rat Model of Depression than in Normal Rats (vol 64, pg 231, 2010). Synapse. 65. 10.1002/syn.20940. 
16. Booij, Linda & Turecki, G & Leyton, Marco & Gravel, P & lara, C. & Diksic, Mirko & Benkelfat, Chawki. (2011). Tryptophan hydroxylase(2) gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans. Molecular psychiatry. 17. 809-17. 10.1038/mp.2011.79. 
17. Nishi, Kyoko & Takahashi, Sho & Diksic, Mirko. (2011). Densities of Serotonergic Projections as Revealed by In Situ Synthesised Labelled α-Methyl-Serotonin: an Autoradiographic Evaluation. Neurochemical research. 36. 1353-9. 10.1007/s11064-011-0454-x. 
18. Skelin, Ivan & Kovacevic, Tomislav & Sato, Hiroki & Diksic, Mirko. (2011). Upregulated arachidonic acid signalling in the olfactory bulbectomized rat model of depression. Neurochemistry international. 58. 483-8. 10.1016/j.neuint.2010.12.022. 
19. Sato, Hiroki & Skelin, Ivan & Diksic, Mirko. (2011). Acute desipramine treatment reduces regional serotonin synthesis rates, while chronic treatment elevates rates, in a rat model of depression: An autoradiographic study. Neurochemistry international. 58. 10.1016/j.neuint.2011.02.024. 
20. Berney, Alexandre & Leyton, Marco & Gravel, Paul & Sibon, Igor & Sookman, Debbie & Rosa, Pedro & Diksic, Mirko & Nakai, Akio & Pinard, Gilbert & Todorov, Christo & Okazawa, Hidehiko & Blier, Pierre & Nordahl, Thomas & Benkelfat, Chawki. (2011). Brain Regional α-[C]Methyl-L-Tryptophan Trapping in Medication-Free Patients With Obsessive-Compulsive Disorder. Archives of general psychiatry. 68. 732-41. 10.1001/archgenpsychiatry.2011.16. 

Profile Details

http://www.bic.mni.mcgill.ca/PeopleFaculty/DiksicMirko