Biography

Dr. Edward Lee Nelson

Division of Hematology/Oncology, Medical Center

University of California, USA

Associate Professor

Email: [email protected]

Qualifications

1986 Ph.D., Medicine, Oregon Health Sciences University


Publications (Selected)

  1. Li, E. Y., Butkovich, N., Tucker, J. A., et al. (2026). Nanoparticle-mediated dual delivery of MHC class I and II antigens enhances T cell immunity and anti-tumor potency. Biomaterials, 333, Article 124128.
  2. Lee, B. J., Griffin, S. P., Doh, J., et al. (2025). R-DA-EPOCH versus DA-EPOCH-R: Impact of chemoimmunotherapy sequencing on treatment outcomes in patients with diffuse large B-cell lymphoma. Clinical Lymphoma Myeloma & Leukemia, 25(12), e1014-e1021.
  3. Saito, H., Nourollahi, S., Alsharif, M. N., et al. (2025). Improving central line-associated bloodstream infection prevention practices in oncology clinic patients: Mobile-app based surveillance & response. Infection Control & Hospital Epidemiology, 46(5), 465-471.
  4. Loukinov, D., Anderson, A. L., Mkrtichyan, M., et al. (2023). A therapeutic vaccine targeting rat BORIS (CTCFL) for the treatment of rat breast cancer tumors. International Journal of Molecular Sciences, 24(6), Article 5976.
  5. Butkovich, N., Tucker, J. A., Ramirez, A., et al. (2023). Nanoparticle vaccines can be designed to induce pDC support of mDCs for increased antigen display. Biomaterials Science, 11(2), 596-610.
  6. Li, E. Y., Brennan, C. K., Ramirez, A., et al. (2022). Macromolecular assembly of bioluminescent protein nanoparticles for enhanced imaging. Materials Today Bio, 17, Article 100455.
  7. Juat, D. J., Hachey, S. J., Billimek, J., et al. (2022). Adoptive T-cell therapy in advanced colorectal cancer: A systematic review. The Oncologist, 27(3), 210-219.
  8. Agbayani, C.-J., Tucker, J. A., Nelson, E. L., et al. (2022). Immunological and psychosocial functioning in parents of children with cancer. Supportive Care in Cancer, 30(4), 3379-3388.
  9. Denney, J. M., Nelson, E., Wadhwa, P., et al. (2021). Cytokine profiling: Variation in immune modulation with preterm birth vs. uncomplicated term birth identifies pivotal signals in pathogenesis of preterm birth. Journal of Perinatal Medicine, 49(3), 299-309.
  10. Neek, M., Tucker, J. A., Butkovich, N., et al. (2020). An antigen-delivery protein nanoparticle combined with anti-PD-1 checkpoint inhibitor has curative efficacy in an aggressive melanoma model. Advanced Therapeutics, 3(12), Article 2000122.
  11. Tucker, J. A., Neek, M., Wang, S.-W., et al. (2020). A novel protein nanoparticle antigen delivery platform combined with checkpoint inhibition has curative efficacy in the aggressive B16-F10 melanoma model. Cancer Research, 80(16, Suppl. S), Abstract 2223.
  12. Osann, K., Wilford, J., Wenzel, L., et al. (2019). Relationship between social support, quality of life, and Th2 cytokines in a biobehavioral cancer survivorship trial. Supportive Care in Cancer, 27(9), 3301-3310.
  13. Fruehauf, K. R., Kim, T. I., Nelson, E. L., et al. (2019). Metabolite responsive nanoparticle-protein complex. Biomacromolecules, 20(7), 2703-2712.
  14. Qiu, X., Lombardo, J. A., Westerhof, T. M., et al. (2018). Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab on a Chip, 18(18), 2776-2786.
  15. Nelson, E. L., Westerhof, T., Giammo, G., et al. (2018). A window into human tumor progenitor cell subsets: Functionalizing a novel platform, the micropallet array, for molecular evaluation of single adherent cells with defined cell surface phenotype. Cancer Research, 78(13, Suppl. S), Abstract 3700.
  16. Bagaev, A., Pichugin, A., Nelson, E. L., et al. (2018). Anticancer mechanisms in two murine bone marrow-derived dendritic cell subsets activated with TLR4 agonists. The Journal of Immunology, 200(8), 2656-2669.
  17. Garg, N., Westerhof, T. M., Liu, V., et al. (2018). Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming. Microsystems & Nanoengineering, 4, Article 17085.
  18. Qiu, X., Huang, J.-H., Westerhof, T. M., et al. (2018). Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Scientific Reports, 8, Article 2774.
  19. Siwy, Z. S., Hinkle, P., Westerhof, T. M., et al. (2018). Deformability of individual cells probed by electrical and optical signals. Biophysical Journal, 114(3, Suppl. 1), 192A.
  20. Neek, M., Tucker, J. A., Kim, T. I., et al. (2018). Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. Biomaterials, 156, 194-203.


Profile Details
https://faculty.uci.edu/profile/?facultyId=4910
https://medschool.uci.edu/about/leadership-faculty/faculty/enelson

WOS ReaearchID: GAX-1530-2022

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