Dr. Edward Lee Nelson
Division of Hematology/Oncology, Medical Center
University of California, USA
Associate Professor
Email: [email protected]
Qualifications
1986 Ph.D., Medicine, Oregon Health Sciences University
Publications (Selected)
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Li, E. Y., Butkovich, N., Tucker, J. A., et al. (2026). Nanoparticle-mediated dual delivery of MHC class I and II antigens enhances T cell immunity and anti-tumor potency. Biomaterials, 333, Article 124128.
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Lee, B. J., Griffin, S. P., Doh, J., et al. (2025). R-DA-EPOCH versus DA-EPOCH-R: Impact of chemoimmunotherapy sequencing on treatment outcomes in patients with diffuse large B-cell lymphoma. Clinical Lymphoma Myeloma & Leukemia, 25(12), e1014-e1021.
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Saito, H., Nourollahi, S., Alsharif, M. N., et al. (2025). Improving central line-associated bloodstream infection prevention practices in oncology clinic patients: Mobile-app based surveillance & response. Infection Control & Hospital Epidemiology, 46(5), 465-471.
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Loukinov, D., Anderson, A. L., Mkrtichyan, M., et al. (2023). A therapeutic vaccine targeting rat BORIS (CTCFL) for the treatment of rat breast cancer tumors. International Journal of Molecular Sciences, 24(6), Article 5976.
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Butkovich, N., Tucker, J. A., Ramirez, A., et al. (2023). Nanoparticle vaccines can be designed to induce pDC support of mDCs for increased antigen display. Biomaterials Science, 11(2), 596-610.
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Li, E. Y., Brennan, C. K., Ramirez, A., et al. (2022). Macromolecular assembly of bioluminescent protein nanoparticles for enhanced imaging. Materials Today Bio, 17, Article 100455.
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Juat, D. J., Hachey, S. J., Billimek, J., et al. (2022). Adoptive T-cell therapy in advanced colorectal cancer: A systematic review. The Oncologist, 27(3), 210-219.
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Agbayani, C.-J., Tucker, J. A., Nelson, E. L., et al. (2022). Immunological and psychosocial functioning in parents of children with cancer. Supportive Care in Cancer, 30(4), 3379-3388.
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Denney, J. M., Nelson, E., Wadhwa, P., et al. (2021). Cytokine profiling: Variation in immune modulation with preterm birth vs. uncomplicated term birth identifies pivotal signals in pathogenesis of preterm birth. Journal of Perinatal Medicine, 49(3), 299-309.
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Neek, M., Tucker, J. A., Butkovich, N., et al. (2020). An antigen-delivery protein nanoparticle combined with anti-PD-1 checkpoint inhibitor has curative efficacy in an aggressive melanoma model. Advanced Therapeutics, 3(12), Article 2000122.
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Tucker, J. A., Neek, M., Wang, S.-W., et al. (2020). A novel protein nanoparticle antigen delivery platform combined with checkpoint inhibition has curative efficacy in the aggressive B16-F10 melanoma model. Cancer Research, 80(16, Suppl. S), Abstract 2223.
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Osann, K., Wilford, J., Wenzel, L., et al. (2019). Relationship between social support, quality of life, and Th2 cytokines in a biobehavioral cancer survivorship trial. Supportive Care in Cancer, 27(9), 3301-3310.
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Fruehauf, K. R., Kim, T. I., Nelson, E. L., et al. (2019). Metabolite responsive nanoparticle-protein complex. Biomacromolecules, 20(7), 2703-2712.
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Qiu, X., Lombardo, J. A., Westerhof, T. M., et al. (2018). Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells. Lab on a Chip, 18(18), 2776-2786.
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Nelson, E. L., Westerhof, T., Giammo, G., et al. (2018). A window into human tumor progenitor cell subsets: Functionalizing a novel platform, the micropallet array, for molecular evaluation of single adherent cells with defined cell surface phenotype. Cancer Research, 78(13, Suppl. S), Abstract 3700.
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Bagaev, A., Pichugin, A., Nelson, E. L., et al. (2018). Anticancer mechanisms in two murine bone marrow-derived dendritic cell subsets activated with TLR4 agonists. The Journal of Immunology, 200(8), 2656-2669.
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Garg, N., Westerhof, T. M., Liu, V., et al. (2018). Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming. Microsystems & Nanoengineering, 4, Article 17085.
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Qiu, X., Huang, J.-H., Westerhof, T. M., et al. (2018). Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue. Scientific Reports, 8, Article 2774.
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Siwy, Z. S., Hinkle, P., Westerhof, T. M., et al. (2018). Deformability of individual cells probed by electrical and optical signals. Biophysical Journal, 114(3, Suppl. 1), 192A.
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Neek, M., Tucker, J. A., Kim, T. I., et al. (2018). Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. Biomaterials, 156, 194-203.
Profile Details
https://faculty.uci.edu/profile/?facultyId=4910
https://medschool.uci.edu/about/leadership-faculty/faculty/enelson
WOS ReaearchID: GAX-1530-2022