Dr. Mary J. Kelley

Casey EyeInstitute

Oregon Health & Science University, USA

Associate Professor

Email: [email protected]

Qualifications

Publications (Selected)

1. Karimi, A., Aga, M., Stanik, A., Franca, C., Siadat, S. M., White, E., ... & Acott, T. (2025). Matrix stiffness regulates traction forces, cytoskeletal dynamics, and collagen reorganization in trabecular meshwork cells in glaucoma. Matter.
2. Karimi, A., Razaghi, R., Stanik, A., D'costa, S. D., Mirafzal, I., Kelley, M. J., ... & Gong, H. (2025). High-resolution modeling of aqueous humor dynamics in the conventional outflow pathway of a normal human donor eye. Computer Methods and Programs in Biomedicine, 260, 108538.
3. Karimi, A., Aga, M., Khan, T., D'costa, S. D., Thaware, O., White, E., ... & Acott, T. S. (2024). Comparative analysis of traction forces in normal and glaucomatous trabecular meshwork cells within a 3D, active fluid-structure interaction culture environment. Acta Biomaterialia, 180, 206-229.
4. Karimi, A., Aga, M., Khan, T., D'costa, S. D., Cardenas-Riumallo, S., Zelenitz, M., ... & Acott, T. S. (2024). Dynamic traction force in trabecular meshwork cells: A 2D culture model for normal and glaucomatous states. Acta biomaterialia, 175, 138-156.
5. Karimi, A., Khan, S., Razaghi, R., Aga, M., Rahmati, S. M., White, E., ... & Acott, T. S. (2024). Segmental biomechanics of the normal and glaucomatous human aqueous outflow pathway. Acta biomaterialia, 173, 148-166.
6. Karimi, A., Razaghi, R., D'costa, S. D., Torbati, S., Ebrahimi, S., Rahmati, S. M., ... & Gong, H. (2024). Implementing new computational methods for the study of JCT and SC inner wall basement membrane biomechanics and hydrodynamics. Computer methods and programs in biomedicine, 243, 107909.
7. Karimi, A., Razaghi, R., Kelley, M. J., Acott, T. S., & Gong, H. (2023). Biomechanics of the JCT and SC inner wall endothelial cells with their basement membrane using 3D serial block-face scanning electron microscopy. Bioengineering, 10(9), 1038.
8. Karimi, A., Khan, S., Razaghi, R., Rahmati, S. M., Gathara, M., Tudisco, E., ... & Acott, T. S. (2023). Developing an experimental-computational workflow to study the biomechanics of the human conventional aqueous outflow pathway. Acta biomaterialia, 164, 346-362.
9. Karimi, A., Crouch, D. J., Razaghi, R., Downs, J. C., Acott, T. S., Kelley, M. J., ... & Sheridan, C. M. (2023). Morphological and biomechanical analyses of the human healthy and glaucomatous aqueous outflow pathway: imaging-to-modeling. Computer methods and programs in biomedicine, 236, 107485.
10. Karimi, A., Razaghi, R., Rahmati, S. M., Downs, J. C., Acott, T. S., Kelley, M. J., ... & Johnstone, M. (2022). The effect of intraocular pressure load boundary on the biomechanics of the human conventional aqueous outflow pathway. Bioengineering, 9(11), 672.
11. Acott, T. S., Vranka, J. A., Keller, K. E., Raghunathan, V., & Kelley, M. J. (2021). Normal and glaucomatous outflow regulation. Progress in retinal and eye research, 82, 100897.
12. Li, X., Acott, T. S., Nagy, J. I., & Kelley, M. J. (2020). ZO-1 associates with α3 integrin and connexin43 in trabecular meshwork and Schlemm’s canal cells. International Journal of Physiology, Pathophysiology and Pharmacology, 12(1), 1.
13. Keller, K. E., Bhattacharya, S. K., Borrás, T., Brunner, T. M., Chansangpetch, S., Clark, A. F., ... & Stamer, W. D. (2018). Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Experimental eye research, 171, 164-173.
14. Acott, T. S., Kelley, M. J., Keller, K. E., Vranka, J. A., Abu-Hassan, D. W., Li, X., ... & Bradley, J. M. (2016). IOP Homeostasis-Why most people do not ever develop glaucoma. Glaucoma research and clinical advances, 2018, 87-98.

Profile Details

https://orcid.org/0000-0002-0372-5096

https://www.ohsu.edu/people/mary-j-kelley

https://scholar.google.com/citations?user=jZKC74UAAAAJ&hl=en

https://www.researchgate.net/profile/Mary-Kelley-14