Email: [email protected]

Qualifications

2004 Ph.D., Bulgarian Academy of Sciences, Bulgarian

Publications(Selected)

1. Naydenova, Z.G., K. Grancharov, D. Alargov, E. Golovinsky, I. Stanoeva, L. Shalamanova, I. Pajeva. Inhibition of UDP-glucuronosyltransferase by 5'-O-amino acid and oligopeptide derivatives of uridine: structure-activity relationships.Zeitshrift fur Naturforschung, 53c,1998, 173-181.
2. Tsakovska, I., I. Pajeva. Molecular modeling of triazine type MDR modulators using CoMFA and CoMSIA approaches.SAR QSAR Environ. Res., 13(3-4),2002, 487-498.
3. Tsakovska, I. QSAR and 3D QSAR of phenothiazine type multidrug resistance modulators in P388/ADR cells.Bioorg. Med. Chem., 11(13),2003, 2889-2899.
4. Tsakovska, I., M. Wiese, I. Pajeva. Molecular modeling of phenothiazines and structurally related multidrug resistance modulators. Comparative study in human and animal tumor cell lines.Biotechnol. & Biotechnol. Eq., 17(2),2003, 163 – 169.
5. Pajeva, I., C. Globisch, R. Fleischer, I. Tsakovska, M. Wiese. Molecular modeling of P-glycoprotein and related drugs.Med. Chem. Res., 14(2),2005, 106-117.
6. Bogdanova, S., I. Pajeva, P. Nikolova, I. Tsakovska, B. Muller. Interactions of poly(vinylpyrrolidone) with ibuprofen and naproxen: experimental and modeling studies.Pharm. Res., 22(5),2005, 806-815.
7. Tsakovska, I., M. Pinto-Bazurco, I. Pajeva. Structure-function relationships and rational design of receptor tyrosine kinase inhibitors,Pharmacia, 52(3),2005, 11-15.
8. Pinto-Bazurko, M., I. Tsakovska, I. Pajeva. QSAR and 3D QSAR of inhibitors of the epidermal growth factor receptor,Int. J. Quant. Chem., 106(6),2006, 1432-1444.
9. Tsakovska, I., I. Lessigiarska, T. Netzeva, I. Pajeva, A. Worth. Review of quantitative structure–activity relationships for acute mammalian toxicity.Bioautomation, 5,2006, 90-105.
10. Tsakovska, I., I. Pajeva. Phenothiazines and structurally related compounds as modulators of cancer multidrug resistance.Curr. Drug Targets, 7(9),2006, 1123-1134.
11. Vračko, M., V. Bandelj, P. Barbieri, E. Benfenati, Q. Chaudhry, M. Cronin, J. Devillers, A.G. Saliner, G. Gini, P. Gramatica, C. Helma, P. Mazzatorta, D. Neagu, T. Netzeva, M. Pavan, G. Patlewicz, M. Randić, I. Tsakovska, A. Worth. Validation of counter propagation neural network models for predictive toxicology according to the OECD principles: a case study.SAR QSAR Environ. Res., 17(3),2006, 265-284.
12. Worth, A.P., A. Bassan, J. de Bruijn, A.G. Saliner, T. Netzeva, G. Patlewicz, M. Pavan, I. Tsakovska, S. Eisenreich. The role of the European Chemicals Bureau in promoting the regulatory use of (Q)SAR methods.SAR QSAR Environ. Res., 18(1-2),2007, 111-125.
13. Tsakovska, I., A.G. Saliner, T. Netzeva, M. Pavan, A.P. Worth. Evaluation of SARs for the prediction of eye irritation/corrosion potential - structural inclusion rules in the BfR decision support system.SAR QSAR Environ. Res., 18(3-4),2007, 221-235.
14. Saliner, A.G., I. Tsakovska, M. Pavan, G. Patlewicz, A. Worth. Evaluation of SARs for the prediction of skin irritation/corrosion potential. Structural inclusion rules in the BfR decision support system.SAR QSAR Environ. Res., 18(3-4),2007, 331-342.
15. Benigni, R., C. Rossa, T. Netzeva, A. Rodomonte, I. Tsakovska. Mechanistic QSAR of Aromatic Amines: New Models for Discriminating between Mutagens and Nonmutagens, and Validation of Models for Carcinogens.Environ. Mol. Mutagen., 48(9),2007, 754-771.
16. Tsakovska, I., I. Lessigiarska, T. Netzeva, A.P. Worth. A Mini Review of Mammalian Toxicity (Q)SAR Models,QSAR Comb Sci., 27(1),2008, 41-48.
17. Tsakovska I., A. Worth. The Use of Computational Methods for the Assessment of Chemicals in REACH. Bioautomation, 13(4),2009, 151-162.
18. Tsakovska I., I. Pjeva, P Alov, A. Worth. Recent Advances in the Molecular Modelling of Estrogen Receptor-Mediated Toxicity, In: Christo Christov, editor: Advances in Protein Chemistry and Structural Biology, Vol. 85, Burlington: Academic Press,2011, pp. 217-251, ISBN: 978-0-12-386485-7

Profile Details

https://biomed.bas.bg/en/ivanka-tsakovska/

https://www.researchgate.net/profile/Ivanka-Tsakovska

https://scholar.google.bg/citations?user=-isqcL0AAAAJ&hl=en