Prof. Keertan Dheda

University of Cape Town, South Africa

Email: keertan.dheda@uct.ac.za

Qualifications

2005 Ph.D., Royal Free and University College Medical School, London, UK

Publications (selected)

1. Scott, Alex & Perumal, Tahlia & Pooran, Anil & Oelofse, Suzette & Jaumdally, Shameem & Swanepoel, Jeremi & Gina, Phindile & Mthiyane, Thuli & Qin, Zhi Zhen & Fehr, Jana & Grant, Alison & Wong, Emily & Walt, Martie & Esmail, Ali & Dheda, Keertan. (2025). Clinical evaluation of computer-aided digital x-ray detection of pulmonary tuberculosis during community-based screening or active case-finding: a case–control study. The Lancet Global Health. 13. e517-e527. 10.1016/S2214-109X(24)00516-3.

2. Dheda, Keertan & Perumal, Tahlia & Fox, Greg. (2025). Asymptomatic tuberculosis: undetected and underestimated, but not unimportant. The Lancet. 10.1016/S0140-6736(25)00555-0.

3. Londt, Rolanda & Semple, Lynn & Esmail, Ali & Pooran, Anil & Meldau, Richard & Davids, Malika & Dheda, Keertan & Tomasicchio, Michele. (2025). Autologous Human Dendritic Cells from XDR-TB Patients Polarize a Th1 Response Which Is Bactericidal to Mycobacterium tuberculosis. Microorganisms. 13. 345. 10.3390/microorganisms13020345.

4. Kim, Sun & Can, Melike & Agizew, Tefera & Auld, Andrew & Balcells, Maria & Bjerrum, Stephanie & Dheda, Keertan & Dorman, Susan & Esmail, Ali & Fielding, Katherine & Garcia-Basteiro, Alberto & Hanrahan, Colleen & Kebede, Wakjira & Kohli, Mikashmi & Luetkemeyer, Anne & Mita, Carol & Reeve, Byron & Silva, Denise & Sweeney, Sedona & Menzies, Nicolas. (2025). Factors associated with tuberculosis treatment initiation among bacteriologically negative individuals evaluated for tuberculosis: An individual patient data meta-analysis. PLOS Medicine. 22. 10.1371/journal.pmed.1004502.

5. Sivarasu, Sudesh & Sander, Grant & Mbanefo, Chibuike & Dheda, Keertan. (2025). Finite Element Analysis and Time Integration for Simulating Time-Dependent Mechanical Loading in a Head Positioning Device. 10.2139/ssrn.5167353.                                                          

6. Shinde, Vivek & Koen, Anthonet & Hoosain, Zaheer & Archary, Moherndran & Bhorat, Qasim & Fairlie, Lee & Lalloo, Umesh & Masilela, Mduduzi & Moodley, Dhayendre & Hanley, Sherika & Fouche, Leon & Louw, Cheryl & Tameris, Michele & Singh, Nishanta & Goga, Ameena & Dheda, Keertan & Grobbelaar, Coert & Joseph, Natasha & Lombaard, Johan & Madhi, Shabir. (2024). Immunogenicity and safety following a homologous booster dose of a SARS-CoV-2 recombinant spike protein vaccine with Matrix-M adjuvant (NVX-CoV2373) versus a primary series in people living with and without HIV-1 infection in South Africa: A randomized crossover phase 2a/2b trial. Human Vaccines & Immunotherapeutics. 20. 2425147. 10.1080/21645515.2024.2425147.

7. Lange, Christoph & Mandalakas, Anna & Lillebaek, Troels & Chesov, Dumitru & Dheda, Keertan & Saluzzo, Francesca. (2024). Revisiting diagnostics: High priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we don’t. Clinical Microbiology and Infection. 31. 10.1016/j.cmi.2024.12.020.

8. Dheda, Keertan & Lange, Christoph. (2024). Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis. The Lancet Respiratory Medicine. 12. 10.1016/S2213-2600(24)00300-X.

9. Voysey, Merryn & Ann, Sue & Clemens, Costa & Madhi, Shabir & Weckx, Lily & Folegatti, Pedro & Aley, Parvinder & Angus, Brian & Baillie, Vicky & Barnabas, Shaun & Bhorat, Qasim & Bibi, Sagida & Briner, Carmen & Cicconi, Paola & Collins, Andrea & Colin-Jones, Rachel & Cutland, Clare & Darton, Thomas & Dheda, Keertan & Perumal, Rubeshan. (2024). Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

10. Christopher, Devasahayam & Esmail, Ali & Scott, Alex & Wilson, Lindsay & Randall, Philippa & Balamugesh, Thangakunam & Shankar, Deepa & Rajasekar, Sekar & Christudass, Christhunesa & Kuhn, Louie & Swanepoel, Jeremi & Perumal, Tahlia & Pooran, Anil & Oelofse, Suzette & Dheda, Keertan. (2024). Diagnostic Performance of Unstimulated IFN-γ (IRISA-TB) for Pleural Tuberculosis: A Prospective Study in South Africa and India. Open Forum Infectious Diseases. 11. 10.1093/ofid/ofae533.

11. Geric, Coralie & Tavaziva, Gamuchirai & Breuninger, Marianne & Dheda, Keertan & Esmail, Ali & Scott, Alex & Kagujje, Mary & Muyoyeta, Monde & Reither, Klaus & Khan, Aamir & Benedetti, Andrea & Ahmad Khan, Faiz. (2024). Breaking the threshold: Developing multivariable models using computer-aided chest X-ray analysis for tuberculosis triage. International Journal of Infectious Diseases. 147. 107221. 10.1016/j.ijid.2024.107221.

12. Randall, Philippa & Mutsvangwa, Junior & Nliwasa, Marriott & Wilson, Lindsay & Makamure, Beauty & Makambwa, Edson & Meldau, Richard & Dheda, Keertan & Munyati, Shungu & Siddiqi, Omar & Corbett, Liz & Esmail, Ali. (2024). Utility of Cerebrospinal Fluid Unstimulated Interferon Gamma (IRISA-TB) as a Same-Day Test for TB Meningitis in a TB-Endemic Resource-Poor Setting. Open Forum Infectious Diseases. 11. 10.1093/ofid/ofae496.

13. Bradshaw, Catherine & Dheda, Keertan & Esmail, Aliasgar & Sivarasu, Sudesh. (2024). Design of a Newpleural Biopsy Device for Improved Procedural Efficacy. 10.1115/DMD2024-1046.

14. Goletti, Delia & Banaei, Niaz & Batra, Rahul & Berger, Anne & Blazevic, Azra & Botelho-Nevers, Elisabeth & Breen, Ronan & Bruiners, Natalie & Cambau, Emmanuelle & Carbonnelle, Etienne & Daley, Charles & Descotes-Genon, Cécile & Di Gennaro, Francesco & Doucet-Populaire, Florence & Esmail, Ali & Guzman, Julia & Fontana, Luc & Gennaro, Maria & Handler, Deborah & Dheda, Keertan. (2024). VIDAS ® TB-IGRA accuracy in tuberculosis patients and persons at varying risk of exposure. 10.1101/2024.07.03.24309158.

15. Lienhardt, Christian & Nahid, Payam & Wells, Charles & Ryckman, Theresa & Kendall, Emily & Davies, Gerry & Brigden, Grania & Churchyard, Gavin & Cirillo, Daniela & Meco, Eugenia & Gopinath, Ramya & Mitnick, Carole & Scott, Cherise & Amanullah, Farhana & Bansbach, Cathy & Boeree, Martin & Campbell, Michael & Conradie, Francesca & Schumacher, Samuel. (2024). Target regimen profiles for tuberculosis treatment. Bulletin of the World Health Organization. 102. 600-607. 10.2471/BLT.24.291881.

16. Scott, Alex & Limbada, Mohammed & Perumal, Tahlia & Jaumdally, Shameem & Kotzé, Andrea & Merwe, Charnay & Cheeba, Maina & Kaluba-Milimo, Deborah & Murphy, Keelin & Ginneken, Bram & Kock, Mariana & Warren, Robin & Gina, Phindile & Swanepoel, Jeremi & Kuhn, Louie & Oelofse, Suzette & Pooran, Anil & Esmail, Ali & Ayles, Helen & Dheda, Keertan. (2024). Integrating molecular and radiological screening tools during community-based active case-finding for tuberculosis and COVID-19 in southern Africa. International Journal of Infectious Diseases. 145. 107081. 10.1016/j.ijid.2024.107081.

17. Kim, Sun & Can, Melike & Agizew, Tefera & Auld, Andrew & Balcells, María Elvira & Bjerrum, Stephanie & Dheda, Keertan & Dorman, Susan & Esmail, Ali & Fielding, Katherine & Garcia-Basteiro, Alberto & Hanrahan, Colleen & Kebede, Wakjira & Kohli, Mikashmi & Luetkemeyer, Annie & Mita, Carol & Reeve, Byron & Silva, Denise & Sweeney, Sedona & Menzies, Nicolas. (2024). Factors associated with tuberculosis treatment initiation among bacteriologically negative individuals evaluated for tuberculosis: an individual patient data meta-analysis. medRxiv : the preprint server for health sciences. 10.1101/2024.04.07.24305445.

18. Dheda, Keertan & Mirzayev, Fuad & Cirillo, Daniela & Udwadia, Zarir & Chang, Kwok-Chiu & Omar, Shaheed & Reuter, Anja & Perumal, Tahlia & Horsburgh, Robert & Murray, Megan & Lange, Christoph. (2024). Multidrug-resistant tuberculosis. Nature Reviews Disease Primers. 10. 10.1038/s41572-024-00504-2.

19. Randall, Philippa & Esmail, Ali & Wilson, Lindsay & Makambwa, Edson & Pooran, Anil & Tomasicchio, Michele & Dheda, Keertan & Ntsekhe, Mpiko. (2024). GeneXpert MTB/RIF Ultra vs Unstimulated Interferon γ (IRISA-TB) for the Diagnosis of Tuberculous Pericarditis in a Tuberculosis-Endemic Setting. Open forum infectious diseases. 11. ofae021. 10.1093/ofid/ofae021.

20. Anand, Apoorva & Vialard, Fiorella & Esmail, Ali & Ahmad Khan, Faiz & O’Byrne, Patrick & Routy, Jean-Pierre & Dheda, Keertan & Pai, Nitika. (2024). Self-tests for COVID-19: What is the evidence? A living systematic review and meta-analysis (2020–2023). PLOS Global Public Health. 4. e0002336. 10.1371/journal.pgph.0002336.

Profile Details

https://health.uct.ac.za/cidri-africa/contacts/keertan-dheda