Prof. Basil
Rigas
Division of
Gastroenterology and Hepatology
Stony Brook
University, USA
E-mail: [email protected]
Qualifications
1977
Internship/Residency, Department of Medicine, Brown University
1975 DSc. (Biochemistry; with highest distinction), Athens University Medical School,
Greece
1972 M.D.
(summa cum laude), Athens University Medical School, Greece
Publications (Selected)
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Khwaja, I. A., Master, A., Honkanen, R., & Rigas, B. (2024). Ex Vivo Drug Evaluation Using Human Ocular Cells: A Contribution to Drug Discovery. Journal of Ophthalmology Research Reviews & Reports. SRC/JORRR-185. DOI: doi. org/10.47363/JORRR/2024 (5), 166, 2-2.
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Khwaja, F., Honkanen, R. A., & Rigas, B. (2024). Animal models of Dry Eye Disease: Application to Drug Discovery. Medical Research Archives, 12(3).
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Basu, A., Yang, J. Y., Tsirukis, V. E., Loiacono, A., Koch, G., Khwaja, I. A., ... & Rigas, B. (2024). Phosphosulindac (OXT-328) prevents and reverses chemotherapy induced peripheral neuropathy in mice. Frontiers in Neuroscience, 17, 1240372.
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Huang, W., Huang, L., Wen, Z., Honkanen, R. A., & Rigas, B. (2023). The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy. Journal of Ocular Pharmacology and Therapeutics, 39(4), 279-289.
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Huang, W., Huang, L., Li, W., Saglam, M. S., Tourmouzis, K., Goldstein, S. M., ... & Rigas, B. (2022). Once-Daily Topical Phosphosulindac Is Efficacious in the Treatment of Dry Eye Disease: Studies in Rabbit Models of Its Main Clinical Subtypes. Journal of Ocular Pharmacology and Therapeutics, 38(1), 102-113.
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Master, A., Huang, W., Huang, L., Honkanen, R., & Rigas, B. (2022). An improved ocular impression cytology method: Quantitative cell transfer to microscope slides using a novel polymer. Current eye research, 47(1), 41-50.
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Master, A., Huang, W., Huang, L., Li, W., Saglam, S., Honkanen, R., & Rigas, B. (2021). Simplified ex-vivo drug evaluation in ocular surface cells: Culture on cellulose filters of cells obtained by impression cytology. Experimental Eye Research, 213, 108827.
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Huang, W., Huang, L., Tsioulias, A., Wen, Z., Saglam, S., Goldstein, S. M., ... & Rigas, B. (2022). Hydrogel formulation of phosphosulindac allows once-a-day ocular dosing and limits its biodistribution to the anterior chamber: Application to dry eye disease treatment. Journal of Drug Delivery Science and Technology, 67, 102961.
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Huang, W., Tourmouzis, K., Perry, H., Honkanen, R. A., & Rigas, B. (2021). Animal models of dry eye disease: Useful, varied and evolving. Experimental and Therapeutic Medicine, 22(6), 1394.
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Master, A., Kontzias, A., Huang, L., Huang, W., Tsioulias, A., Zarabi, S., ... & Rigas, B. (2021). The transcriptome of rabbit conjunctiva in dry eye disease: Large-scale changes and similarity to the human dry eye. Plos one, 16(7), e0254036.
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Huang, W., Wen, Z., Saglam, M. S., Huang, L., Honkanen, R. A., & Rigas, B. (2021). Phospho-Sulindac (OXT-328) inhibits dry eye disease in rabbits: a dose-, formulation-and structure-dependent effect. Journal of Ocular Pharmacology and Therapeutics, 37(6), 321-330.
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Honkanen, R., Nemesure, B., Huang, L., & Rigas, B. (2021). Diagnosis of dry eye disease using principal component analysis: A study in animal models of the disease. Current Eye Research, 46(5), 622-629.
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Honkanen, R. A., Huang, L., & Rigas, B. (2020). A rabbit model of aqueous-deficient dry eye disease induced by concanavalin A injection into the lacrimal glands: Application to drug efficacy studies. Journal of Visualized Experiments (JoVE), (155), e59631.
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Luo, D., Fraga-Lauhirat, M., Millings, J., Ho, C., Villarreal, E. M., Fletchinger, T. C., ... & Mackenzie, G. G. (2019). Phospho-valproic acid (MDC-1112) suppresses glioblastoma growth in preclinical models through the inhibition of STAT3 phosphorylation. Carcinogenesis, 40(12), 1480-1491.
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Rigas, B., Huang, W., & Honkanen, R. A. (2019). Commentary: NSAID-Induced Corneal Melt: Clinical Importance, Pathogenesis and Risk Mitigation. Journal of Immunological Sciences, 3(4).
Profile Details
https://www.stonybrook.edu/experts/profile/basil-rigas
https://www.researchgate.net/profile/Basil-Rigas