Prof. Zheng Dong

Medical college of Georgia

Augusta University, USA

Professor

Medical Research/Nephrology

Charlie Norwood VA Medical Center, USA

Scientist

Email: [email protected]

Publications (Selected)

1. Wei, Q., Xiao, X., Huo, E., Guo, C., Zhou, X., Hu, X., ... & Dong, Z. (2025). Hypermethylation and suppression of microRNA219a-2 activates the ALDH1L2/GSH/PAI-1 pathway for fibronectin degradation in renal fibrosis. Molecular Therapy, 33(1), 249-262.
2. Tang, C., & Dong, Z. (2025). Ubiquitin-independent mitophagy: mechanisms and pathophysiological functions. In Mitophagy in Health and Disease (pp. 25-41). Academic Press.
3. Chen, H., Song, J., Zeng, L., Zha, J., Zhu, J., Chen, A., ... & Chen, G. (2024). Dietary sodium modulates mTORC1-dependent trained immunity in macrophages to accelerate CKD development. Biochemical Pharmacology, 229, 116505.
4. Wei, Q., Huang, J., Livingston, M. J., Wang, S., Dong, G., Xu, H., ... & Dong, Z. (2024). Pseudogene GSTM3P1 derived long non-coding RNA promotes ischemic acute kidney injury by target directed microRNA degradation of kidney-protective mir-668. Kidney International, 106(4), 640-657.
5. Robichaud, J. H., Zhang, Y., Chen, C., He, K., Huang, Y., Zhang, X., ... & Hu, J. (2024). Transiently formed nucleus-to-cilium microtubule arrays mediate senescence initiation in a KIFC3-dependent manner. Nature communications, 15(1), 7977.
6. Xiao, X., Wang, W., Guo, C., Wu, J., Zhang, S., Shi, H., ... & Dong, Z. (2024). Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis. Kidney International, 106(1), 98-114.
7. Xu, X., Huang, W., Bryant, C. N., Dong, Z., Li, H., & Wu, G. (2024). The ufmylation cascade controls COPII recruitment, anterograde transport, and sorting of nascent GPCRs at ER. Science Advances, 10(25), eadm9216.
8. Livingston, M. J., Zhang, M., Kwon, S. H., Chen, J. K., Li, H., Manicassamy, S., & Dong, Z. (2024). Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair. Autophagy, 20(5), 1032-1053.
9. Fu, Y., Xiang, Y., Wei, Q., Ilatovskaya, D., & Dong, Z. (2024). Rodent models of AKI and AKI-CKD transition: an update in 2024. American Journal of Physiology-Renal Physiology, 326(4), F563-F583.
10. Fu, Y., Xiang, Y., Wei, Q., Ilatovskaya, D., & Dong, Z. (2024). Rodent models of AKI and AKI-CKD transition: an update in 2024. American Journal of Physiology-Renal Physiology, 326(4), F563-F583.
11. Deng, Z., Wang, Y., Liu, J., Zhang, H., Zhou, L., Zhao, H., ... & Deng, F. (2023). WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury. Redox Biology, 65, 102826.
12. Zhu, J., Xiang, X., Hu, X., Li, C., Song, Z., & Dong, Z. (2023). miR-147 represses NDUFA4, inducing mitochondrial dysfunction and tubular damage in cold storage kidney transplantation. Journal of the American Society of Nephrology, 34(8), 1381-1397.
13. Tran, G. B., Ding, J., Ye, B., Liu, M., Yu, Y., Zha, Y., ... & Ding, H. F. (2023). Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma. Cancer Research, 83(13), 2248-2261.
14. Fu, Y., Xiang, Y., Wang, Y., Liu, Z., Yang, D., Zha, J., ... & Dong, Z. (2023). The STAT1/HMGB1/NF-κB pathway in chronic inflammation and kidney injury after cisplatin exposure. Theranostics, 13(9), 2757.
15. Liu, J. L., Zhang, L., Huang, Y., Li, X. H., Liu, Y. F., Zhang, S. M., ... & Xiao, L. (2023). Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy. Molecular Therapy, 31(5), 1451-1467.
16. Li, S., Livingston, M. J., Ma, Z., Hu, X., Wen, L., Ding, H. F., ... & Dong, Z. (2023). Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity. JCI insight, 8(8), e166643.
17. Ma, Q., Yang, Q., Xu, J., Sellers, H. G., Brown, Z. L., Liu, Z., ... & Huo, Y. (2023). Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models. European heart journal, 44(14), 1265-1279.

Profile Details

https://www.augusta.edu/mcg/cba/faculty/dong.php

https://scholar.google.com/citations?user=MF9zZOsAAAAJ&hl=en