Prof. Kenneth Richard Boheler

Johns Hopkins University, USA

Email: [email protected]

Qualifications

1988 Ph.D., Physiology and Pharmacology, University of California, USA

1982 B.Sc., Zoology, Duke University, USA

Publications(Selected)

1. Hall, F. D., III, Miller, C., & Gerecht, S., et al. (2026). Generation of an induced pluripotent stem cell line, JHUi006-A, from a Marfan Syndrome patient harboring a pathogenic c. 5225-2A> C intronic splicing variant. Stem Cell Research, Article 103915.
2. Kissling, M., Wu, S. C. M., & Swethakumar, M., et al. (2026). Dynamic mechanical response in a human stem cell-derived smooth muscle cell model. APS Global Physics Summit 2026.
3. Wu, B., Chen, J. C. H., & Ma, C. H. Y., et al. (2026). ICG-001 provides cardioprotection against doxorubicin-induced cardiotoxicity and enhances cancer cytotoxicity. Basic to Translational Science, 11(2), Article 101459.
4. Wu, S. C. M., Boheler, K. R. (2026). Generation of an induced pluripotent stem cell and isogenic control line from a vascular Ehlers-Danlos Syndrome (vEDS) patient harboring a pathogenic c. 755G> T in the COL3A1 gene. Stem Cell Research, Article 103945.
5. Wu, S. C. M., DiSilvestre, D., & Tomaselli, G. F., et al. (2026). Generation of induced pluripotent stem cell (JHUi009-A) and isogenic control (JHUi009-A-1) lines from a patient with vascular Ehlers-Danlos syndrome (vEDS) harboring a pathogenic c. 755G> T variant in the COL3A1 gene. Stem Cell Research, Article 104023.
6. Chua, C. J., DiSilvestre, D., & Joshi-Mukherjee, R., et al. (2025). Generation of an induced pluripotent stem cell line, JHUi008-A, from a healthy female donor. Stem Cell Research, Article 103819.
7. Huang, C. Y., Wu, S. C. M., & Kissling, M., et al. (2025). Phenotypes and cellular mechanics of primary human aorta- and pluripotent stem cell-derived vascular smooth muscle cells. bioRxiv, 2025.12.18.694995.
8. Wu, S. C. M., Kissling, M., & Reich, D., et al. (2025). Abstract Thu001: Dysregulated p38 MAPK signaling drives hypercontractility in vascular Ehlers-Danlos syndrome smooth muscle cells. Circulation Research, 137(Suppl_1).
9. Hall, F. D., III, Miller, C. N., & Gerecht, S., et al. (2024). Generation of an induced pluripotent stem cell line, JHUi005-A, from a Marfan Syndrome patient harboring a pathogenic c. 3338-2A> C intronic splicing variant. Stem Cell Research, 79, Article 103475.
10. Kissling, M., Huang, C. Y., & Chen, Y. W., et al. (2024). Control of cellular phenotype in a human stem cell-derived smooth muscle cell model. APS March Meeting Abstracts 2024, B38.004.
11. Morrissette-McAlmon, J., Chua, C. J., & Arking, A., et al. (2024). Adipocyte-mediated electrophysiological remodeling of PKP-2 mutant human pluripotent stem cell-derived cardiomyocytes. Biomedicines, 12(11), Article 2601.
12. Morrissette-McAlmon, J., Xu, W. R., & Teuben, R., et al. (2024). Adipocyte-mediated electrophysiological remodeling of human stem cell-derived cardiomyocytes. Journal of Molecular and Cellular Cardiology, 189, 52–65.
13. Berg Luecke, L., Waas, M., & Littrell, J., et al. (2023). Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts. Nature Cardiovascular Research, 2(1), 76–95.
14. Chua, C. J., Morrissette-McAlmon, J., & Tung, L., et al. (2023). Understanding arrhythmogenic cardiomyopathy: Advances through the use of human pluripotent stem cell models. Genes, 14(10), Article 1864.
15. Li, S., Yan, B., & Wu, B., et al. (2023). Integrated modeling framework reveals co-regulation of transcription factors, miRNAs and lncRNAs on cardiac developmental dynamics. Stem Cell Research & Therapy, 14(1), Article 247.
16. Wu, S. C. M., Zhu, M., & Chik, S. C. C., et al. (2023). Adipose tissue-derived human mesenchymal stromal cells can better suppress complement lysis, engraft and inhibit acute graft-versus-host disease in mice. Stem Cell Research & Therapy, 14(1), Article 167.
17. Mair, D. B., Williams, M. A. C., & Teuben, R., et al. (2022). A high-throughput functional screening platform for determining the effects of galactic cosmic radiation on human cardiac tissue. Tissue Engineering Part A, 28, S624–S624.
18. Stoddart, L., Mair, D. B., & Teuben, R., et al. (2022). Engineered heart tissue microphysiological system identified oxidative and mitochondrial stress due to exposure to galactic cosmic radiation. Tissue Engineering Part A, 28, 239–240.
19. Murphy, S. A., Chen, E. Z., & Tung, L., et al. (2021). Maturing heart muscle cells: Mechanisms and transcriptomic insights. Seminars in Cell & Developmental Biology, 119, 49–60.

Profile Details
https://www.bme.jhu.edu/people/faculty/kenneth-boheler/
https://scholar.google.com/citations?user=rt1VgzMAAAAJ&hl=en

WOS ResearcherID: EOL-8598-2022