Prof. Rupert Leong

University of Sydney, Australia

E-mail: [email protected]

Qualifications

2004 Fellow of the Royal Australasian College of Physicians Doctor of Medicine, Chinese University of Hong Kong, China

1994 Bachelor of Medicine. Bachelor of Surgery (UWA)

Publications (Selected)

1. Porcari, S., Mullish, B. H., Asnicar, F., Ng, S. C., Zhao, L., Hansen, R., ... & Ianiro, G. (2025). International consensus statement on microbiome testing in clinical practice. The Lancet Gastroenterology & Hepatology, 10(2), 154-167.
2. Leong, R. W., Sakiris, A., Arzivian, A., Chetwood, J. D., Chaemsupaphan, T., Sparrow, M. P., ... & Australian IBD Consensus Working Group. (2025). Consensus Statements on Assessments and Vaccinations Prior to Commencement of Advanced Therapies for the Treatment of Inflammatory Bowel Diseases. Alimentary Pharmacology & Therapeutics, 61(1), 132-144.
3. Gilmore, R., Fernandes, R., Hartley, I., Arzivian, A., Leong, R., Andrew, B., ... & Begun, J. (2024). Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study. Intestinal Research.
4. Gilmore, R., Fernandes, R., Hartley, I., Arzivian, A., Leong, R., Andrew, B., ... & Begun, J. (2024). Upadacitinib induction is effective and safe in ulcerative colitis patients including those with prior exposure to tofacitinib: a multicenter real-world cohort study. Intestinal Research.
5. Chaemsupaphan, T., Leong, R. W., Vande Casteele, N., & Seow, C. H. (2024). Optimisation of biologic (monoclonal antibody) therapeutic response in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 60(9), 1234-1243.
6. Swaminathan, A., Fulforth, J. M., Frampton, C. M., Borichevsky, G. M., Mules, T. C., Kilpatrick, K., ... & Gearry, R. B. (2024). The disease severity index for inflammatory bowel disease is a valid instrument that predicts complicated disease. Inflammatory bowel diseases, 30(11), 2064-2075.
7. Majzoub, M. E., Paramsothy, S., Haifer, C., Parthasarathy, R., Borody, T. J., Leong, R. W., ... & Kaakoush, N. O. (2024). The phageome of patients with ulcerative colitis treated with donor fecal microbiota reveals markers associated with disease remission. Nature Communications, 15(1), 8979.
8. Chetwood, J. D., Tran, Y., Subramanian, S., Smith, P. J., Iborra, M., Buisson, A., ... & Leong, R. W. (2024). Intravenous versus subcutaneous infliximab in inflammatory bowel disease: A systematic review and meta-analysis. Journal of Crohn's and Colitis, 18(9), 1440-1449.
9. Chetwood, J. D., Paramsothy, S., Haifer, C., Borody, T. J., Kamm, M. A., Leong, R. W., & Kaakoush, N. O. (2024). Key metabolomic alterations are associated with ulcerative colitis disease state and activity: a validation analysis. Gut, 73(8), 1392-1393.
10. Smith, P. J., Fumery, M., Leong, R. W., Novak, K., & Dignass, A. (2023). Real-world experience with subcutaneous infliximab: broadening treatment strategies for inflammatory bowel disease. Expert Review of Clinical Immunology, 19(9), 1143-1156.
11. Laube, R., Selinger, C. P., Seow, C. H., Christensen, B., Flanagan, E., Kennedy, D., ... & Leong, R. W. (2023). Australian inflammatory bowel disease consensus statements for preconception, pregnancy and breast feeding. Gut, 72(6), 1040-1053.
12. Feagan, B. G., Sands, B. E., Sandborn, W. J., Germinaro, M., Vetter, M., Shao, J., ... & Ritter, T. (2023). Guselkumab plus golimumab combination therapy versus guselkumab or golimumab monotherapy in patients with ulcerative colitis (VEGA): a randomised, double-blind, controlled, phase 2, proof-of-concept trial. The Lancet Gastroenterology & Hepatology, 8(4), 307-320.
13. Louis, E., Resche-Rigon, M., Laharie, D., Satsangi, J., Ding, N., Siegmund, B., ... & Roblin, X. (2023). Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial. The Lancet Gastroenterology & Hepatology, 8(3), 215-227.
14. Pudipeddi, A., Fung, C., Christensen, B., Bryant, R. V., Subramaniam, K., Chetwood, J., ... & Leong, R. W. (2023). Knowledge and attitudes towards the use of histological assessments in ulcerative colitis by gastroenterologists vs pathologists. World Journal of Gastroenterology, 29(2), 378.
15. Haifer, C., Luu, L. D. W., Paramsothy, S., Borody, T. J., Leong, R. W., & Kaakoush, N. O. (2023). Microbial determinants of effective donors in faecal microbiota transplantation for UC. Gut, 72(1), 90-100.
16. Tamilarasan, A. G., Tran, Y., Paramsothy, S., & Leong, R. (2022). The diagnostic yield of pan‐enteric capsule endoscopy in inflammatory bowel disease: A systematic review and meta‐analysis. Journal of Gastroenterology and Hepatology, 37(12), 2207-2216.

Profile Details

https://orcid.org/0000-0001-5944-3488

https://www.sydney.edu.au/medicine-health/about/our-people/academic-staff/rupert-leong.html%C2%A0

https://scholar.google.com.hk/citations?user=zAS8uq4AAAAJ&hl=en