Dr. Georges Nemer
American University of Beirut, Lebanon
Email: [email protected]
Qualifications
2008 Associate Professor, American University of Beirut,
Biochemistry and Molecular Genetics
2002 Ph.D.,
Universite de Montreal
Publications (Selected)
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Fahed A,Nemer G.Familial Hypercholesterolemia:The Lipids or
the Genes?Nutrition and Metabolism (Accepted March 2011)
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El-Hachem N,Nemer G. Identification of New GATA4-Small
Molecule Inhibitors by Structure-Based Virtual Screening.Bioorganic and
Medicinal Chemistry19(5):1734-42 (2011)
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Fahed AC, Safa RM, Haddad FF, Bitar FF, Andary RR, Arabi MT,
Azar ST,Nemer G.Homozygous familial hypercholesterolemia in Lebanon: A
genotype/phenotype correlation. Mol Genet Metab.102(2):181-8 (2011)
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Shaib H., Cochet N., Ribeiro T., Abdel Nour A.,Nemer G.,
Barbour E. Pathogenicity and amino acid sequence variability in the HA1 protein
of differently passaged H9N2 Avian Influenza virus.Medical Science
Monitor16(10):BR333-7(2010)
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Nemer Gand Nemer M. Tbx5 et l’adaptation du cœur à la vie
sur terre.Médecine-Sciences26(8-9):699-700(2010)
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HantoucheC.,Nemer G., Obeid M., Kadi L., Der-Boghossian H.,
Bikhazi A. Role of Glucagon-Like Peptide -1 (GLP-1) analogues on insulin
receptor regulation in diabetic rat heart.Can. J. Physiol. Pharmacol. 88(1):
54–63(2010)
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Posch M., Gramlich M., Sunde M., Schmitt K., Panek A.,
Perrot A., Dietz R., Al-Khatib I,Nemer G. , Mégarbané A., Berger F., Harvey
R.,ÖzcelikC.A gain-of-functionTbx20mutation causes human congenital cardiac
atrial septal and valve defects.J Med Genet47(4):230-5(2010)
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Abou-Jawdah Y., Atamian H., Nemer G., Kfoury L.,Choukrallah
N., Hanna L., Nemer N. Efficacy and molecular studies of a Lebanese isolate
ofBeauveriafor the biocontrol ofThaumetopoea wilkinsoni (Lepidoptera :
Thaumetopoeidae).Biocontrol Science & Technology.18 (6):581-89(2008)
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GeorgesR *,Nemer G.*, Lefebvre C, Nemer M. Distinct
Expression and Function of Alternatevily Spliced Tbx5 Isoforms in Cell Growth
and Differentiation.Mol Cell Biol.28(12):4052-67(2008)(* Co-first author)
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Hammud H., Nemer G., Sawma W., Touma J., Barnabe P.,
Bou-Mouglabey Y., Ghannoum A., El-Hajjar J., Usta J. Copper Adenine Complex, a
compound, with multi-biochemical targets and potential anti-cancer effect.Chem
Biol Interact.28;173(2):84-96(2008)
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Nourredine L., Azzam R., Nemer G., Bielawski J., Nasser M.,
Bitar F., Dbaibo G. Modulation of total ceramide and constituent ceramide
species in the acutely and chronically hypoxic mouse heart at different
ages.Prostaglandins & Other Lipid Mediators86(1-4):49-55(2008).
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Abdo, C., Nemer, N.,Nemer G., Abou Jawdah, Y, and Kawar,
N.S. Molecular identification ofBeauveriaspp. in Lebanon and evaluating its
efficacy against the cedar web-spinning
sawfly,Cephalciatannourinensis.BioControl53:341-352(2008)
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El-Rassi I., Bou-Abdallah J., Al-Ghadban S, Bitar F., Nemer
G. Absence of NOTCH2 and Hey2 Mutations in a Familial Alagille Syndrome Case
with a Novel FrameShift Mutation in JAG1.AmericanJournal of Medical Genetics
(A)146(7):937-9(2008)
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Barada K.,Nemer G., ElHajj I., Touma J.,Cortas N., Boustany RM,and
Usta J.Early and severe liver disease associated with homozygosity for an exon
7 mutation, G691R, in Wilson's disease .Clinical Genetics72(3):264-7 (2007)
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Arabi M, Majdalani M, Nemer G, and Bitar F. Molecular
markers of congenital heart disease.Congenital Cardiology Today5(3):1-8 (2007)
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Habib A., Shamseddeen I., Nasrallah M., Abi Antoun T.,Nemer
G., Bertoglio J., Badreddine R., and Badr K. Modulation of Cox-2 expression by
statins in human monocytic cells.FASEB21:1665-1674(2007)
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Yamak A, Karam P, Bitar F,Nemer G.Exclusive cardiac
dysfunction in familial primary carnitine deficiency cases: a
genotype-phenotype correlation.Clinical Genetics72:59-62 (2007)
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Lavallée G, Andelfinger G,Nadeau M, Lefebvre C,Nemer G, Horb
M,Nemer M.KLF13, a novel GATA-4 cofactor and regulator of
cardiogenesis.EMBO25:5201-5213 (2006)
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Yehya A, Souki R, Bitar F, andNemer G. Differential
Duplication of an Intronic Region in the NFATc1 Gene in Patients with
Congenital Heart Disease.Genome49(9):1092-1098 (2006)
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Nemer G, Fadlalah F, Usta J, Nemer M,Dbaibo G, Obeid M, and
Bitar F. A novel mutation in the GATA4 gene in patients with Tetralogy of
Fallot.Human Mutation27(3):293-4 (2006)
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Alwani M, Usta J,Nemer G, El-Sabban M, Bitar H, Nasser M,
Souki R, Dbaibo G, Bitar F. Regulation of the Sphingolipid Signaling Pathways
in the Growing and Hypoxic Rat Heart.Prostaglandins & Other Lipid
Mediators78(1-4):249-63 (2005)
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Abou-Jawdah Y, Sobh H, Cordahi N, Kawtharani H,Nemer G,
Maxwell D, and Nakhla M : Immunodiagnosis of Prune dwarf virus using antiserum
produced to its recombinant coat protein.J Virol Methods.121(1):31-8 (2004)
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Nemer G, Nemer M : Transcriptional activation of BMP-4 and
regulation of mammalian organogenesis GATA-4 and GATA-6.Developmental
Biology254, 131-148 (2003)
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Alison Brewer,Georges Nemer, Chris Gove, Francesca Rawlins,
Mona Nemer, Roger Patient, John Pizzey :Widespread expression of an extended
peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of
RNA and protein expression domains.Gene Expr Patterns. 2(1-2):123-3 (2002)
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Nemer G and Nemer M : Cooperative interaction between GATA-5
and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic
cells.Development129, 4045-4055 (2002)
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Nemer G and Nemer M : Regulation of heart development and
function through combinatorial interactions of transcription factors.Annals of
Medicine33, pp 604-610 (2001)
Profile Details
https://www.aub.edu.lb/fm/DBMG/Pages/GeorgesNemerLab.aspx
https://orcid.org/0000-0003-2157-5279
https://sciprofiles.com/profile/GeorgesNemer