Dr. Jian-Xin Gao

Department of Laboratory of Tumor Development and Immunity
Renji Clinical Stem Cell Center
Shanghai Jiao Tong University School of Medicine, China

Email:  [email protected]

Qualifications

1989 Ph.D., Immunology and Microbiology, Shanghai Medical University, China

1986 M.S., Microbiology and Immunology, Suzhou Medical College, China

1982 M.D., Suzhou Medical College, China

Publications (Selected)

1. Liu, Y. W., Gao, J. X., Ye, J. Y., et al. (2025). Cupriavidus gilardii infection following heart failure: A case report and literature review. BMC Infectious Diseases, 25(1), Article 169.
2. Chen, Y. Z., Liu, B., Tao, S. S., et al. (2025). CITED2 binding to EP300 regulates human spermatogonial stem cell proliferation and survival through HSPA6. Stem Cells International, 2025(1), Article 2362489.
3. Sun, L., Hui, F., Tang, G. Y., et al. (2024). Selective degradation of PL2L60 by metabolic stresses-induced autophagy suppresses multi-cancer growth. Oncology Reports, 51(3), Article 41.
4. Lu, Y. P., Yu, M., Ye, J. S., et al. (2023). Sauchinone inhibits the proliferation and immune invasion capacity of colorectal cancer cells through the suppression of PD-L1 and MMP2/MM9. Anti-Cancer Agents in Medicinal Chemistry, 23(12), 1406–1414.
5. Lu, H. M., Fu, Y. J., Liu, N., et al. (2022). A novel tumor-specific broad-spectral monoclonal antibody to PL2L60 is highly effective for the treatment of various types of cancers from human and mouse. American Journal of Cancer Research, 12(1), 265–279.
6. Pang, S. X., Jia, M., Gao, J. X., et al. (2021). Effects of dietary patterns combined with dietary phytochemicals on breast cancer metastasis (vol 264, 118720, 2021). Life Sciences, 286, Article 120034.
7. Pang, S. X., Jia, M., Gao, J. X., et al. (2021). Effects of dietary patterns combined with dietary phytochemicals on breast cancer metastasis. Life Sciences, 264, Article 118720.
8. Liu, X. X., Chen, H. Y., Hou, Y. L., et al. (2019). Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway. International Journal of Oncology, 54(4), 1466–1480.
9. Chen, H. Y., Xie, H. Y., Liu, X. X., et al. (2019). Splenic irradiation combined with tumor irradiation promotes T cell infiltration in the tumor microenvironment and helps in tumor control. Biochemical and Biophysical Research Communications, 510(1), 156–162.
10. Chen, H. Y., Xu, L., Li, L. F., et al. (2018). Inhibiting the CD8+ T cell infiltration in the tumor microenvironment after radiotherapy is an important mechanism of radioresistance. Scientific Reports, 8, Article 11934.
11. Liu, S. S., Liu, N., Liu, M. Y., et al. (2017). An unusual intragenic promoter of PIWIL2 contributes to aberrant activation of oncogenic PL2L60. Oncotarget, 8(28), 46104–46120.
12. Cao, H. L., Xu, M. Q., Dong, W. X., et al. (2017). Secondary bile acid-induced dysbiosis promotes intestinal carcinogenesis. International Journal of Cancer, 140(11), 2545–2556.
13. Gao, J. X., Wang, X. J., Wang, Y. C., et al. (2016). Murine Sertoli cells promote the development of tolerogenic dendritic cells: A pivotal role of galectin-1. Immunology, 148(3), 253–265.
14. Sun, L., Xia, W. Y., Zhao, S. H., et al. (2016). An asymmetrically dimethylarginated nuclear 90 kDa protein (p90aDMA) induced by interleukin (IL)-2, IL-4 or IL-6 in the tumor microenvironment is selectively degraded by autophagy. International Journal of Oncology, 48(6), 2461–2471.
15. Gao, J. X., Lu, H. M., Fu, Y. J., et al. (2016). Targeting PIWIL2-like (PL2L) proteins by a monoclonal antibody for immunotherapy of both solid and hematopoietic cancers. Journal of Clinical Oncology, 34(15_suppl), Article e14001.
16. Liu, N., Xia, W. Y., Liu, S. S., et al. (2016). MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition. Scientific Reports, 6, Article 20489.

Profile Details
https://bme.sjtu.edu.cn/En/Show/517
https://www.researchgate.net/scientific-contributions/Jian-Xin-Gao-2079327380
https://www.emedevents.com/speaker-profile/jian-xin-gao

WOS ResearcherID: JED-4101-2023