Dr. Umberto Galderisi

Second University of Napoli, Italy

Email: [email protected]

Qualifications

1992 Ph.D., Dept. of Genetics, University “Federico II”, Italy

1987 B.Sc., Biology, University “Federico II”, Italy

Publications (Selected)

1. Di Bernardo G, Alessio N, Dell'aversana C, Casale F, Teti D, Cipollaro M, Altucci L, Galderisi U. Impact of histone deacetylase inhibitors SAHA and MS-275  on DNA repair pathways in human mesenchymal stem cells. J Cell Physiol. 2010 May 10. [Epub ahead of print]
2. Symonds CE, Galderisi U, Giordano A. Aging of the inceptive cellular population: the relationship between stem cells and aging. Aging (Albany NY). 2009 Apr 2;1(4):372-81.
3. Squillaro T, Alessio N, Cipollaro M, Renieri A, Giordano A, Galderisi U. Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA. FASEB J. 2010 May;24(5):1593-603.
4. Siniscalco D, Giordano C, Galderisi U, Luongo L, Alessio N, Di Bernardo G, de  Novellis V, Rossi F, Maione S. Intra-brain microinjection of human mesenchymal stem cells decreases allodynia in neuropathic mice. Cell Mol Life Sci. 2010 Feb;67(4):655-69.
5. Di Bernardo G, Galderisi U, Fiorito C, Squillaro T, Cito L, Cipollaro M, Giordano A, Napoli C. Dual role of parathyroid hormone in endothelial progenitor  cells and marrow stromal mesenchymal stem cells. J Cell Physiol. 2010 Feb;222(2):474-80.
6. Melone MA, Giuliano M, Squillaro T, Alessio N, Casale F, Mattioli E, Cipollaro M, Giordano A, Galderisi U. Genes involved in regulation of stem cell properties: studies on their expression in a small cohort of neuroblastoma patients. Cancer Biol Ther. 2009 Jul;8(13):1300-6.
7. Galderisi U, Helmbold H, Squillaro T, Alessio N, Komm N, Khadang B, Cipollaro  M, Bohn W, Giordano A. In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes. Stem Cells Dev. 2009 Sep;18(7):1033-42.
8. Galderisi U, Helmbold H, Squillaro T, Alessio N, Komm N, Khadang B, Cipollaro M, Bohn W, Giordano A. In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes. Stem Cells Dev. 2008 Dec 19.
9. Tirino V, Desiderio V, d'Aquino R, De Francesco F, Pirozzi G, Graziano A, Galderisi U, Cavaliere C, De Rosa A, Papaccio G, Giordano A. Detection and characterization of CD133+ cancer stem cells in human solid tumours. PLoS ONE. 2008;3(10):e3469. Epub 2008 Oct 21. Erratum in: PLoS ONE. 2008;3(12).
10. Di Bernardo G, Squillaro T, Dell'aversana C, Miceli M, Cipollaro M, Cascino A, Altucci L, Galderisi U. Histone Deacetylase Inhibitors Promote Apoptosis and Senescence in Human Mesenchymal Stem Cells. Stem Cells Dev. 2008 Aug 11.
11. Forte A, Finicelli M, Mattia M, Berrino L, Rossi F, De Feo M, Cotrufo M, Cipollaro M, Cascino A, Galderisi U. Mesenchymal stem cells effectively reduce surgically induced stenosis in rat carotids. J Cell Physiol. 2008 Dec;217(3):789-99.
12. Squillaro T, Hayek G, Farina E, Cipollaro M, Renieri A, Galderisi U. A case report: bone marrow mesenchymal stem cells from a Rett syndrome patient are prone to senescence and show a lower degree of apoptosis. J Cell Biochem. 2008 Apr 15;103(6):1877-85.