Prof. Eva Corey
University of
Washington, USA
Email: [email protected]
Qualifications
1989 Ph.D.,
Czechoslovak Academy of Sciences, Czechoslovakia
1987 M.Sc., Charles
University, Czechoslovakia
1985 B.Sc., Charles
University, Czechoslovakia
Publications (selected)
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Sekar, A., Selvadurai, B.R., Chatterjee, R., Pal, L., Verma, A., Belugali Nataraj, N. and others. TMPRSS2-ERG confers resistance of prostate cancer to antiandrogens. EMBO Molecular Medicine, 1-36, 2026.
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Guersetti, F.E., Mojtahedzadeh, B., Xie, D., Koohbor, S., Corey, E., Haffner, M.E. and others. Abstract LB244: Osteosclerosis is associated to low anaplastic histological patterns in prostate cancer bone metastasis. Cancer Research, 86(8_Supplement), LB244, 2026.
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Jeon, H.Y., Khadka, S., Pornour, M., Ryu, H., Chen, H., Hussain, A., Lam, H.M. and others. BPTF regulates androgen receptor activity in prostate cancer. Cancer Research, 86(7_Supplement), 7247, 2026.
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Lin, K.M., Seidl, A., Waldman, T., Li, X., Corey, E., Sowalsky, A.G. and Kotula, L. Alternative splicing of ABI1 by enzalutamide treatment drives tumor plasticity in prostate cancer. Cancer Research, 86(7_Supplement), 4763, 2026.
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Hartono, A.B., Hwang, H.J., Paparaju, S., Liu, S., Brooks, J.D., Corey, E. and others. CDC7 is a targetable regulator of advanced prostate cancer. Scientific Reports, 2025.
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Tarun, M.T.I., Ebrahim, H.Y., Dawud, D., Elmageed, Z.Y.A., Corey, E. and El Sayed, K.A. The Olive Phenolic S–(–)–Oleocanthal as a Novel Intervention for Neuroendocrine Prostate Cancers: Therapeutic and Molecular Insights. Nutrients, 17(24), 3947, 2025.
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Jeon, H.Y., Khadka, S., Pornour, M., Ryu, H., Chen, H., Hussain, A., Lam, H.M. and others. BPTF regulates androgen receptor activity by enhancing chromatin accessibility and stabilizing the AR-FOXA1 interaction. Nature Communications, 2025.
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Ma, F., Chen, S., Cecchi, L., Ersoy-Fazlioglu, B., Russo, J.W., Arai, S., Awad, S. and others. Androgen deprivation–mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion. The Journal of Clinical Investigation, 135(23), 2025.
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Westaby, D., Jiménez-Vacas, J.M., Figueiredo, I., Rekowski, J., Pettinger, C. and others. BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity. The Journal of Clinical Investigation, 134(18), 2024.
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Xu, P., Yang, J.C., Chen, B., Ning, S., Zhang, X., Wang, L., Nip, C., Shen, Y. and others. Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer. Nature Communications, 15(1), 6626, 2024.
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Cheng, S., Li, L., Yeh, Y., Shi, Y., Franco, O., Corey, E. and Yu, X. Unveiling novel double-negative prostate cancer subtypes through single-cell RNA sequencing analysis. NPJ Precision Oncology, 8(1), 171, 2024.
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Yin, J.J., Daryanani, A., Lu, F., Ku, A.T., Bright, J.R., Alilin, A.N.S., Bowman, J. and others. Reproducible preclinical models of androgen receptor driven human prostate cancer bone metastasis. The Prostate, 84(11):1033-1046, 2024.
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Sugawara, T., Nevedomskaya, E., Heller, S., Böhme, A., Lesche, R. and others. Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis. Molecular Oncology, 18(3):726-742, 2024.
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Franceschini, G.M., Quaini, O., Mizuno, K., Orlando, F., Ciani, Y., Ku, S.Y. and others. Noninvasive detection of neuroendocrine prostate cancer through targeted cell-free DNA methylation. Cancer Discovery, 14(3):424-445, 2024.
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Chen, C.C., Tran, W., Song, K., Sugimoto, T., Obusan, M.B., Wang, L., Sheu, K.M. and others. Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation. Cancer Cell, 41(12):2066-2082.e9, 2023.
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Corey, E. Therapeutic Targeting of Neuroendocrine Prostate Cancer. 2023.
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Sandoval, G.J., Centore, R.C., Topal, S., Lahr, D., Elliott, G.N., Gandevia, H. and others. Treatment with dual BRG1/BRM (SMARCA4/2) inhibitor FHD-286 ablates tumor-associated androgen response elements (AREs) in prostate cancer. Proceedings of the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics, 2023.
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Giafaglione, J.M., Crowell, P.D., Delcourt, A.M.L., Hashimoto, T., Ha, S.M. and others. Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment. Nature Cell Biology, 25(12):1821-1832, 2023.
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Zivanovic, A., Miller, J.T., Munro, S.A., Knutson, T.P., Li, Y., Passow, C.N. and others. Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer. NAR Cancer, 5(3), zcad045, 2023.
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Nyquist, M.D., Coleman, I.M., Lucas, J.M., Li, D., Hanratty, B., Meade, H. and others. Supraphysiological androgens promote the tumor suppressive activity of the androgen receptor through cMYC repression and recruitment of the DREAM complex. Cancer Research, 83(17):2938-2951, 2023.
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Schuster, S.L., Arora, S., Wladyka, C.L., Itagi, P., Corey, L., Young, D. and others. Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations. Cell Reports, 42(8), 2023.
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Gritsina, G., Fong, K., Lu, X., Lin, Z., Xie, W., Agarwal, S., Lin, D., Schiltz, G.E. and others. Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth. The Journal of Clinical Investigation, 133(15), 2023.
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Zaalberg, A., Minnee, E., Mayayo-Peralta, I., Schuurman, K., Gregoricchio, S. and others. A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator. bioRxiv, 2023.
Personal Details
WoS Researcher
ID: GBM-5995-2022
https://urology.uw.edu/people/faculty/eva-corey
https://scholar.google.com/citations?user=OTbMBJl7SyEC&hl=en
https://www.researchgate.net/profile/Eva-Corey