Biography

Prof. Beate Koksch

Free University of Berlin, Germany
Professor


Email: [email protected]


Qualifications


1995  PhD, Leipzig University, Biochemistry
1991
Chemistry, Leipzig University


Publications (Selected)

  1. Treiber-Kleinke, C., Göller, J. M., Liba, J., et al. (2026). Genomic signatures highlight stress-response evasion and translational tuning as key drivers of Escherichia coli adaptation to fluorinated tryptophans. Chemical Science, 17(36).
  2. Iannuzzi, M., Fiedler, H., Haoues, K., et al. (2026). Fluorination as a Molecular Design Parameter for Programming Peptide Nanocarriers. Small.
  3. Rathessan, A. P., Ghazisaeedi, F., Unmesh, K., et al. (2026). Structure-Activity Relationship Study of Antimicrobial Peptide with Cross-Kingdom Activity. Biochemistry, 65(12), 1944-1956.
  4. Ge, L., Zaiser, M., & Koksch, B. (2026). Practical Synthesis of Fluorinated Amino Acids: Process Optimization toward Improved Sustainability. Organic Process Research & Development, 30(6), 1602-1614.
  5. Reiter, D., Türk, S., Schubert, M., & Koksch, B. (2026). 1H, 13C, 15N, and 19F random coil NMR shifts of trifluoromethyl-bearing amino acids. Journal of Fluorine Chemistry, 291, Article 110567.
  6. Khan, M. F., Karamanis, P., Koksch, B., & Murphy, C. D. (2026). A hydrolase from Serratia liquefaciens IMD717 with esterase, dehalogenase and N-deformylase activities. Applied Microbiology and Biotechnology, 110(1), Article 167.
  7. Prefontaine, A., Liba, J., Spicer, V., et al. (2026). Reversed-phase chromatography of peptides carrying non-canonical proline analogues, with special focus on 4R/4S-fluoroproline. Journal of Chromatography A, 1769, Article 466704.
  8. Puhlmann, A., Baydaroglu, C., Schade, B., et al. (2025). Metal Ion-Induced Cross-Linking in Mucin-Inspired Peptide Hydrogels. Journal of Peptide Science, 31(11), Article e70059.
  9. Kagelmacher, M., Pigaleva, M., Zarate, R., et al. (2025). HMGB1 B-Box Domain Associates Promote Protein-Polyelectrolyte Interactions. Journal of Physical Chemistry B, 129(37), 9293-9303.
  10. Reiter, D., Mutlu, F., Ebert, D., et al. (2025). Investigating the Site-Specific Impact of Fluorine Substitution on Aromatic Interactions in a Tryptophan Zipper Peptide. Chemistry-A European Journal, 31(40), Article e202501263.
  11. Malicka, W., Kagelmacher, M., Jaworek, M. W., et al. (2025). Redox-dependent structural and thermal stability of HMGB1: A thermodynamic analysis. Biophysical Chemistry, 325, Article 107472.
  12. Iannuzzi, M., Hohmann, T., Dyrks, M., et al. (2025). Asymmetric synthesis of fluorinated derivatives of aromatic and γ-branched amino acids via a chiral Ni(II) complex. Beilstein Journal of Organic Chemistry, 21, 659-669.
  13. Mendes, M., Nunes, S., Cova, T., et al. (2024). Charge-switchable cell-penetrating peptides for rerouting nanoparticles to glioblastoma treatment. Colloids and Surfaces B-Biointerfaces, 241, Article 113983.
  14. Almalla, A., Elomaa, L., Fribiczer, N., et al. (2024). Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization. Biomaterials Advances, 160, Article 213850.
  15. Proksch, J., Dal Colle, M. C. S., Heinz, F., et al. (2024). Impact of glycan nature on structure and viscoelastic properties of glycopeptide hydrogels. Journal of Peptide Science, 30(8).
  16. Langhans, A., Krummhaar, M., Roth, C., & Koksch, B. (2024). Catalytically Competent Fluorinated Barnase Variants. Synlett, 35(9), 1042-1046.
  17. Heinz, F., Proksch, J., Schmidt, R. F., et al. (2024). How Chromophore Labels Shape the Structure and Dynamics of a Peptide Hydrogel. Biomacromolecules, 25(2), 1262-1273.
  18. Vale, N., Ribeiro, E., Cruz, I., et al. (2023). New Perspective for Using Antimicrobial and Cell-Penetrating Peptides to Increase Efficacy of Antineoplastic 5-FU in Cancer Cells. Journal of Functional Biomaterials, 14(12), Article 565.
  19. Almalla, A., Elomaa, L., Bechtella, L., et al. (2023). Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels. Biomacromolecules, 24(12), 5620-5637.
  20. Giesecke, Y., Asimi, V., Stulberg, V., et al. (2023). Is the Neuropeptide PEN a Ligand of GPR83? International Journal of Molecular Sciences, 24(20), Article 15117.
  21. Balke, J., Gutiérrez, P. D., Rafaluk-Mohr, T., et al. (2023). Osmolytes Modulate Photoactivation of Phytochrome: Probing Protein Hydration. Molecules, 28(16), Article 6121.
  22. Hohmann, T., Dubatouka, P., Pfeifer, K., & Koksch, B. (2023). Establishing Fluorine-Containing Amino Acids as an Orthogonal Tool in Coiled Coil Assembly. Biomacromolecules, 24(7), 3357-3369.
  23. Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science & Technology, 57(26), 9762-9772.
  24. Hohmann, T., Chowdhary, S., Ataka, K., et al. (2023). Introducing Aliphatic Fluoropeptides: Perspectives on Folding Properties, Membrane Partition and Proteolytic Stability. Chemistry-A European Journal, 29(23), Article e202203860.
  25. Chowdhary, S., Pelzer, T., Saathoff, M., et al. (2023). Fine-tuning the antimicrobial activity of β-hairpin peptides with fluorinated amino acids. Peptide Science, 115(3).


Profile Details

https://www.bcp.fu-berlin.de/en/chemie/chemie/forschung/OrgChem/koksch/Members/Group_Head/index.html
https://scholar.google.com/citations?user=av8ktmMAAAAJ&hl=en


WOS ResearcherID: FEQ-0158-2022


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