Prof. Beate Koksch
Free University of Berlin, Germany
Professor
Email: [email protected]
Qualifications
1995 PhD, Leipzig University, Biochemistry
1991 Chemistry, Leipzig University
Publications (Selected)
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Treiber-Kleinke, C., Göller, J. M., Liba, J., et al. (2026). Genomic signatures highlight stress-response evasion and translational tuning as key drivers of Escherichia coli adaptation to fluorinated tryptophans. Chemical Science, 17(36).
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Iannuzzi, M., Fiedler, H., Haoues, K., et al. (2026). Fluorination as a Molecular Design Parameter for Programming Peptide Nanocarriers. Small.
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Rathessan, A. P., Ghazisaeedi, F., Unmesh, K., et al. (2026). Structure-Activity Relationship Study of Antimicrobial Peptide with Cross-Kingdom Activity. Biochemistry, 65(12), 1944-1956.
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Ge, L., Zaiser, M., & Koksch, B. (2026). Practical Synthesis of Fluorinated Amino Acids: Process Optimization toward Improved Sustainability. Organic Process Research & Development, 30(6), 1602-1614.
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Reiter, D., Türk, S., Schubert, M., & Koksch, B. (2026). 1H, 13C, 15N, and 19F random coil NMR shifts of trifluoromethyl-bearing amino acids. Journal of Fluorine Chemistry, 291, Article 110567.
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Khan, M. F., Karamanis, P., Koksch, B., & Murphy, C. D. (2026). A hydrolase from Serratia liquefaciens IMD717 with esterase, dehalogenase and N-deformylase activities. Applied Microbiology and Biotechnology, 110(1), Article 167.
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Prefontaine, A., Liba, J., Spicer, V., et al. (2026). Reversed-phase chromatography of peptides carrying non-canonical proline analogues, with special focus on 4R/4S-fluoroproline. Journal of Chromatography A, 1769, Article 466704.
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Puhlmann, A., Baydaroglu, C., Schade, B., et al. (2025). Metal Ion-Induced Cross-Linking in Mucin-Inspired Peptide Hydrogels. Journal of Peptide Science, 31(11), Article e70059.
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Kagelmacher, M., Pigaleva, M., Zarate, R., et al. (2025). HMGB1 B-Box Domain Associates Promote Protein-Polyelectrolyte Interactions. Journal of Physical Chemistry B, 129(37), 9293-9303.
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Reiter, D., Mutlu, F., Ebert, D., et al. (2025). Investigating the Site-Specific Impact of Fluorine Substitution on Aromatic Interactions in a Tryptophan Zipper Peptide. Chemistry-A European Journal, 31(40), Article e202501263.
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Malicka, W., Kagelmacher, M., Jaworek, M. W., et al. (2025). Redox-dependent structural and thermal stability of HMGB1: A thermodynamic analysis. Biophysical Chemistry, 325, Article 107472.
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Iannuzzi, M., Hohmann, T., Dyrks, M., et al. (2025). Asymmetric synthesis of fluorinated derivatives of aromatic and γ-branched amino acids via a chiral Ni(II) complex. Beilstein Journal of Organic Chemistry, 21, 659-669.
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Mendes, M., Nunes, S., Cova, T., et al. (2024). Charge-switchable cell-penetrating peptides for rerouting nanoparticles to glioblastoma treatment. Colloids and Surfaces B-Biointerfaces, 241, Article 113983.
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Almalla, A., Elomaa, L., Fribiczer, N., et al. (2024). Chemistry matters: A side-by-side comparison of two chemically distinct methacryloylated dECM bioresins for vat photopolymerization. Biomaterials Advances, 160, Article 213850.
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Proksch, J., Dal Colle, M. C. S., Heinz, F., et al. (2024). Impact of glycan nature on structure and viscoelastic properties of glycopeptide hydrogels. Journal of Peptide Science, 30(8).
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Langhans, A., Krummhaar, M., Roth, C., & Koksch, B. (2024). Catalytically Competent Fluorinated Barnase Variants. Synlett, 35(9), 1042-1046.
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Heinz, F., Proksch, J., Schmidt, R. F., et al. (2024). How Chromophore Labels Shape the Structure and Dynamics of a Peptide Hydrogel. Biomacromolecules, 25(2), 1262-1273.
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Vale, N., Ribeiro, E., Cruz, I., et al. (2023). New Perspective for Using Antimicrobial and Cell-Penetrating Peptides to Increase Efficacy of Antineoplastic 5-FU in Cancer Cells. Journal of Functional Biomaterials, 14(12), Article 565.
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Almalla, A., Elomaa, L., Bechtella, L., et al. (2023). Papain-Based Solubilization of Decellularized Extracellular Matrix for the Preparation of Bioactive, Thermosensitive Pregels. Biomacromolecules, 24(12), 5620-5637.
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Giesecke, Y., Asimi, V., Stulberg, V., et al. (2023). Is the Neuropeptide PEN a Ligand of GPR83? International Journal of Molecular Sciences, 24(20), Article 15117.
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Balke, J., Gutiérrez, P. D., Rafaluk-Mohr, T., et al. (2023). Osmolytes Modulate Photoactivation of Phytochrome: Probing Protein Hydration. Molecules, 28(16), Article 6121.
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Hohmann, T., Dubatouka, P., Pfeifer, K., & Koksch, B. (2023). Establishing Fluorine-Containing Amino Acids as an Orthogonal Tool in Coiled Coil Assembly. Biomacromolecules, 24(7), 3357-3369.
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Khan, M. F., Chowdhary, S., Koksch, B., & Murphy, C. D. (2023). Biodegradation of Amphipathic Fluorinated Peptides Reveals a New Bacterial Defluorinating Activity and a New Source of Natural Organofluorine Compounds. Environmental Science & Technology, 57(26), 9762-9772.
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Hohmann, T., Chowdhary, S., Ataka, K., et al. (2023). Introducing Aliphatic Fluoropeptides: Perspectives on Folding Properties, Membrane Partition and Proteolytic Stability. Chemistry-A European Journal, 29(23), Article e202203860.
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Chowdhary, S., Pelzer, T., Saathoff, M., et al. (2023). Fine-tuning the antimicrobial activity of β-hairpin peptides with fluorinated amino acids. Peptide Science, 115(3).
Profile Details
https://www.bcp.fu-berlin.de/en/chemie/chemie/forschung/OrgChem/koksch/Members/Group_Head/index.html
https://scholar.google.com/citations?user=av8ktmMAAAAJ&hl=en
WOS ResearcherID: FEQ-0158-2022