Prof. Paul Ducheyne

Department of Bioengineering

University of Pennsylvania, USA
Professor

Email: [email protected]

Qualifications

1976 Doctor's degree, Katholieke Universiteit Leuven, Materials Science

1972 Master of Science, Katholieke Universiteit Leuven, Materials Science and Engineering

1. Jennings, J. A., Arts, J. J., Abuhussein, E., et al. (2024). 2023 International Consensus Meeting on musculoskeletal infection: Summary from the treatment workgroup and consensus on treatment in preclinical models. Journal of Orthopaedic Research, 42(3), 500–511.
2. Woelfle, U. C., Briggs, T., Bhattacharyya, S., et al. (2020). Dual local drug delivery of vancomycin and farnesol for mitigation of MRSA infection in vivo - A pilot study. European Cells & Materials, 40, 38–57.
3. Aboltins, C. A., Antoci, V., Bhattacharyya, S., et al. (2019). Hip and Knee Section, Prevention, Prosthesis Factors: Proceedings of International Consensus on Orthopedic Infections. The Journal of Arthroplasty, 34(2), S309–S320.
4. Pelletier, M. H., Cohen, C. S., Ducheyne, P., et al. (2016). Restoring segmental biomechanics through nucleus augmentation an in vitro study. Clinical Spine Surgery, 29(10), 461–467.
5. Qu, H., Costache, M. C., Inan, S., et al. (2016). Local, controlled delivery of local anesthetics in vivo from polymer - xerogel composites. Pharmaceutical Research, 33(3), 729–738.
6. Qu, H., Bhattacharyya, S., & Ducheyne, P. (2015). Silicon oxide based materials for controlled release in orthopedic procedures. Advanced Drug Delivery Reviews, 94, 96–115.
7. Qu, H., Knabe, C., Radin, S., et al. (2015). Percutaneous external fixator pins with bactericidal micron-thin sol-gel films for the prevention of pin tract infection. Biomaterials, 62, 95–105.
8. Hackett, D. J., Rothenberg, A. C., Chen, A. F., et al. (2015). The economic significance of orthopaedic infections. Journal of the American Academy of Orthopaedic Surgeons, 23(1), S1–S7.
9. Chen, R., Qu, H., Guo, S., et al. (2015). The design and synthesis of a soluble composite silica xerogel and the short-time release of proteins. Journal of Materials Chemistry B, 3(16), 3141–3149.
10. Qu, H., Knabe, C., Burke, M., et al. (2014). Bactericidal micron-thin sol-gel films prevent pin tract and periprosthetic infection. Military Medicine, 179(8), 29–33.
11. Bhattacharyya, S., Agrawal, A., Knabe, C., et al. (2014). Sol-gel silica controlled release thin films for the inhibition of methicillin-resistant Staphylococcus aureus. Biomaterials, 35(1), 509–517.
12. Diaz-Ledezma, C., Parvizi, J., Zhou, Y., et al. (2014). Prosthesis selection. Journal of Orthopaedic Research, 32(S1), S90–S97.
13. Radin, S., Bhattacharyya, S., & Ducheyne, P. (2013). Nanostructural control of the release of macromolecules from silica sol-gels. Acta Biomaterialia, 9(8), 7987–7995.
14. Costache, M. C., Vaughan, A. D., Qu, H., et al. (2013). Tyrosine-derived polycarbonate-silica xerogel nanocomposites for controlled drug delivery. Acta Biomaterialia, 9(5), 6544–6552.
15. Chen, R., Qu, H., Agrawal, A., et al. (2013). Controlled release of small molecules from silica xerogel with limited nanoporosity. Journal of Materials Science: Materials in Medicine, 24(1), 137–146.
16. Bhattacharyya, S., Wang, H., & Ducheyne, P. (2012). Polymer-coated mesoporous silica nanoparticles for the controlled release of macromolecules. Acta Biomaterialia, 8(9), 3429–3435.
17. Ducheyne, P., Mauck, R. L., & Smith, D. H. (2012). Biomaterials in the repair of sports injuries. Nature Materials, 11(8), 652–654.
18. Makarov, C., Gotman, I., Radin, S., et al. (2010). Vancomycin release from bioresorbable calcium phosphate-polymer composites with high ceramic volume fractions. Journal of Materials Science, 45(23), 6320–6324.
19. Bernstein, M., Gotman, I., Makarov, C., et al. (2010). Low temperature fabrication of β-TCP-PCL nanocomposites for bone implants. Advanced Engineering Materials, 12(8), B341–B347.
20. Costache, M. C., Qu, H., Ducheyne, P., et al. (2010). Polymer-xerogel composites for controlled release wound dressings. Biomaterials, 31(24), 6336–6343.
21. Adams, C. S., Antoci, V., Harrison, G., et al. (2009). Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis. Journal of Orthopaedic Research, 27(6), 701–709.
22. Radin, S., Chen, T., & Ducheyne, P. (2009). The controlled release of drugs from emulsified, sol gel processed silica microspheres. Biomaterials, 30(5), 850–858.
23. Toworfe, G. K., Bhattacharyya, S., Composto, R. J., et al. (2009). Effect of functional end groups of silane self-assembled monolayer surfaces on apatite formation, fibronectin adsorption and osteoblast cell function. Journal of Tissue Engineering and Regenerative Medicine, 3(1), 26–36.
24. Antoci, V., Adams, C. S., Parvizi, J., et al. (2008). The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection. Biomaterials, 29(35), 4684–4690.
25. Liu, C., Chen, C., & Ducheyne, P. (2008). In vitro surface reaction layer formation and dissolution of calcium phosphate cement-bioactive glass composites. Biomedical Materials, 3(3), Article 034111.

Profile Details

https://www.engineering.upenn.edu/~bmtlab/ducheyne.html
https://www.researchgate.net/profile/Paul-Ducheyne

WOS ResearcherID: EQP-2125-2022