Prof. Dr. S. M. Abe Kawsar

Lab of Carbohydrate and Nucleoside Chemistry (LCNC)

Department of Chemistry, University of Chittagong

Full Professor

Email: [email protected]

Research fields:

Computational Chemistry, Synthetic Organic Chemistry, Medicinal Chemistry, Carbohydrates and Nucleosides Chemistry, Antimicrobial

Qualifications

1996 B.Sc., Chemistry, University of Chittagong, Chittagong, Bangladesh

1998 M.Sc., Organic Chemistry, University of Chittagong, Chittagong, Bangladesh

2003 M.Phil., Natural Products Chemistry, BUET, Dhaka, Bangladesh

2009 PhD., Glycobiology, Yokohama City University, Japan

2011 Postdoctoral Fellow, Glycobiology, Yokohama City University, Japan

Publications (Selected)

1. Kim, S. K. (Ed.). (2013). Marine proteins and peptides: biological activities and applications. John Wiley & Sons.
2. Fujii, Y., Dohmae, N., Takio, K., Kawsar, S. M., Matsumoto, R., Hasan, I., ... & Ozeki, Y. (2012). A lectin from the mussel Mytilus galloprovincialis has a highly novel primary structure and induces glycan-mediated cytotoxicity of globotriaosylceramide-expressing lymphoma cells. Journal of Biological Chemistry, 287(53), 44772-44783.
3. Hassan, S. A., Aziz, D. M., Abdullah, M. N., Bhat, A. R., Dongre, R. S., Hadda, T. B., ... & Jamalis, J. (2024). In vitro and in vivo evaluation of the antimicrobial, antioxidant, cytotoxic, hemolytic activities and in silico POM/DFT/DNA-binding and pharmacokinetic analyses of new sulfonamide bearing thiazolidin-4-ones. Journal of Biomolecular Structure and Dynamics, 42(7), 3747-3763.
4. Rana, K. M., Maowa, J., Alam, A., Dey, S., Hosen, A., Hasan, I., ... & Kawsar, S. M. (2021). In silico DFT study, molecular docking, and ADMET predictions of cytidine analogs with antimicrobial and anticancer properties. In silico pharmacology, 9(1), 42.
5. Hosen, M. A., Munia, N. S., Al-Ghorbani, M., Baashen, M., Almalki, F. A., Hadda, T. B., ... & Kawsar, S. M. (2022). Synthesis, antimicrobial, molecular docking and molecular dynamics studies of lauroyl thymidine analogs against SARS-CoV-2: POM study and identification of the pharmacophore sites. Bioorganic Chemistry, 125, 105850.
6. Islam, S., Hosen, M. A., Ahmad, S., ul Qamar, M. T., Dey, S., Hasan, I., ... & Kawsar, S. M. (2022). Synthesis, antimicrobial, anticancer activities, PASS prediction, molecular docking, molecular dynamics and pharmacokinetic studies of designed methyl α-D-glucopyranoside esters. Journal of Molecular Structure, 1260, 132761.
7. Kawsar, S. M., Kumer, A., Munia, N. S., Hosen, M. A., Chakma, U., & Akash, S. (2022). Chemical descriptors, PASS, molecular docking, molecular dynamics and ADMET predictions of glucopyranoside derivatives as inhibitors to bacteria and fungi growth. Organic Communications, 15(2), 203.
8. Amin, M. R., Yasmin, F., Hosen, M. A., Dey, S., Mahmud, S., Saleh, M. A., ... & Kawsar, S. M. A. (2021). Synthesis, antimicrobial, anticancer, PASS, molecular docking, molecular dynamic simulations & pharmacokinetic predictions of some methyl β-D-galactopyranoside analogs. Molecules, 26(22), 7016.
9. Kawsar, S. M., Fujii, Y., Matsumoto, R., Ichikawa, T., Tateno, H., Hirabayashi, J., ... & Ozeki, Y. (2008). Isolation, purification, characterization and glycan-binding profile of a D-galactoside specific lectin from the marine sponge, Halichondria okadai. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 150(4), 349-357.
10. Hasan, I., Sugawara, S., Fujii, Y., Koide, Y., Terada, D., Iimura, N., ... & Ozeki, Y. (2015). MytiLec, a mussel R-type lectin, interacts with surface glycan Gb3 on Burkitt’s lymphoma cells to trigger apoptosis through multiple pathways. Marine drugs, 13(12), 7377-7389.
11. Kawsar, S. M. A., Huq, E., Nahar, N., & Ozeki, Y. (2008). Identification and quantification of phenolic acids in Macrotyloma uniflorum by reversed phase-HPLC.
12. MA Kawsar, S., Hosen, M. A., Ahmad, S., El Bakri, Y., Laaroussi, H., Ben Hadda, T., ... & Goumri-Said, S. (2022). Potential SARS-CoV-2 RdRp inhibitors of cytidine derivatives: Molecular docking, molecular dynamic simulations, ADMET, and POM analyses for the identification of pharmacophore sites. PLoS One, 17(11), e0273256.
13. Amin, M. R., Yasmin, F., Dey, S., Mahmud, S., Saleh, M. A., Emran, T. B., ... & Kawsar, S. M. (2022). Methyl β-D-galactopyranoside esters as potential inhibitors for SARS-CoV-2 protease enzyme: synthesis, antimicrobial, PASS, molecular docking, molecular dynamics simulations and quantum computations. Glycoconjugate journal, 39(2), 261-290.
14. Kawsar, S. M., Munia, N. S., Saha, S., & Ozeki, Y. (2024). In silico pharmacokinetics, molecular docking and molecular dynamics simulation studies of nucleoside analogs for drug discovery-a mini review. Mini Reviews in Medicinal Chemistry, 24(11), 1070-1088.
15. Akter, N., Bourougaa, L., Ouassaf, M., Bhowmic, R. C., Uddin, K. M., Bhat, A. R., ... & Kawsar, S. M. (2024). Molecular docking, ADME-Tox, DFT and molecular dynamics simulation of butyroyl glucopyranoside derivatives against DNA gyrase inhibitors as antimicrobial agents. Journal of Molecular Structure, 1307, 137930.

Profile Details

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