Dr. Paolo Governa

Email: [email protected]

Qualifications

2021 Ph.D., University of Siena, Italy

Publications (Selected)

1. Borgonetti V., Governa P., Morozzi M., Sasia C., Videtta G., Biagi M., Galeotti N. “A Standardized Extract of Zingiber officinale Roscoe Regulates Clinical and Biological Outcomes in Two Different EAE Mouse Models”. Biomedicines (2025), 13, 278.
2. Arvia R., Biagi M., Baini G., Cappellucci G., Governa P., Balatri S., Zakrzewska K. "Hylotelephium telephium (L) H. Ohba leaves juice improves herpetic lesions: new findings from in vitro investigations". Natural Product Research (2024), https://doi.org/10.1080/14786419.2024.2423378.
3. Di Maria S., Passannanti R., Poggialini F., Vagaggini C., Serafinelli A., Bianchi E., Governa P., Botta L., Maga G., Crespan E., Manetti F., Dreassi E., Musumeci F., Carbone A., Schenone S. "Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma". european Journal of Medicinal Chemistry (2024), 280, 116929.
4. Governa P., Biagi M., Manetti F., Forli S. "Consensus screening for a challenging target: the quest for P-glycoprotein inhibitors". RSC Medicinal Chemistry (2024), 15, 724-732.
5. Aslan H., Renzi G., Angeli A., D'Agostino I., Ronca R., Massardi M., Tavani C., Carradori S., Ferraroni M., Governa P., Manetti F., Carta F., Supuran C.T. "Benzenesulfonamide Decorated Dihydropyrimidin(thi)ones: Carbonic Anhydrase Profiling and Antiproliferative Activity". RSC Medicinal Chemistry (2024), 15, 1929-1941.
6. Wozniak J.M., Li W., Governa P., Chen, L., Jadhav A., Dongre A., Forli F., Parker C.G. "Enhanced mapping of small-molecule binding sites in cells". Nature Chemical Biology (2024), 20, 823-834.
7. Borgonetti V., Caroli C., Governa P., Brighenti V., Pollastro F., Franchini S., Manetti F., Les F., López V., Pellati F., Galeotti N. "Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol". Phytotherapy Research (2023), 37(10), 4304–4320.
8. Tamburello M., Salamone S., Anceschi L., Governa P., Brighenti V., Morellini A., Rossini G., Manetti F., Gallinella G., Pollastro F., Pellati F. "Antiviral Activity of Cannabidiolic Acid and Its Methyl Ester against SARS-CoV-2". Journal of Natural Products (2023), 86, 7, 1698–1707.
9. Governa P.°*, Romagnoli G.°*, Albanese P., Rossi F., Manetti F., Biagi M. "Effect of in vitro simulated digestion on the anti-Helicobacter Pylori activity of different Propolis extracts". Journal of Enzyme Inhibition and Medicinal Chemistry (2023), 38(1): 2183810.
10. Borgonetti V.°, Governa P.°., Manetti F., Galeotti N. "Zingiberene, a non-zinc-binding class I HDAC inhibitor: a novel strategy for the management of neuropathic pain". Phytomedicine (2023), 111:154670.
11. Pressi G., Rigillo G., Governa P., Borgonetti V., Baini G., Rizzi R., Guarnerio C., Bertaiola O., Frigo M., Merlin M., Paltrinieri S., Zambonin R., Pandolfo S., Biagi M., Basnet S. "A Novel Perilla frutescens (L.) Britton Cell-Derived Phytocomplex Regulates Keratinocytes Inflammatory Cascade and Barrier Function and Preserves Vaginal Mucosal Integrity In Vivo". Pharmaceutics (2023), 15(1), 240.
12. Borgonetti V., Anceschi L., Brighenti V., Corsi L., Governa P., Manetti F., Pellati F., Galeotti N. "Cannabidiol‐rich non‐psychotropic Cannabis sativa L. oils attenuate peripheral neuropathy symptoms by regulation of CB2‐mediated microglial neuroinflammation". Phytotherapy Research (2023), 37(5), 1924–1937.
13. Borgonetti V., Biagi M., Galeotti N., Manetti F., Governa P.* "Investigation on the neuroprotective effect of a cannabidiol-enriched non-psychotropic Cannabis sativa L. extract in an in vitro model of excitotoxicity". Fitoterapia (2022), 163, 105315.
14. Manetti F.*, Maresca L., Crivaro E., Pepe S., Cini E., Singh S., Governa P., Maramai S., Giannini G., Stecca B.*, Petricci E.* "Quinolines and Oxazino-quinoline Derivatives as Small Molecule GLI1 Inhibitors Identified by Virtual Screening". ACS Medicinal Chemistry Letters (2022), 13, 8: 1329–1336.
15. Governa P., Bernardini G., Braconi D., Manetti F., Santucci A., Petricci E. "Survey on the Recent Advances in 4-Hydroxyphenylpyruvate Dioxygenase (HPPD) Inhibition by Diketone and Triketone Derivatives and Congeneric Compounds: Structural Analysis of HPPD/Inhibitor Complexes and Structure–Activity Relationship Considerations". Journal of Agricultural and Food Chemistry (2022), 70(23), 6963–6981.
16. Borgonetti V., Benatti C., Governa P., Isoldi G., Pellati F., Alboni S., Tascedda F., Montopoli M., Galeotti N., Manetti F., Miraldi E., Biagi M., Rigillo G. "Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB‐mediated signaling". Phytotherapy Research (2022), 36(5), 2246– 2263.

Profile Details

https://sites.google.com/site/paologoverna

https://www.webofscience.com/wos/author/record/1392757