Dr. Hui Jin

The Feinstein Institute for Medical Research, Northwell Health, United States

Reasearch Fellow

Email: [email protected]

Qualifications

2017 Postdoc, Neutrophils Heterogeneity, The Feinstein Institute for Medical Research, United States

2013 Ph.D., Stroke Microcirculatory Disorders, Southern Medical University, China

2003 B.S. and M.S., Clinical ,Medicine, Sun Yat-sen University, China

Publications (Selected)

1. Jin H, Aziz M, Atsushi M, et al. Antigen-presenting aged neutrophils induce CD4+ T cells to exacerbate inflammation in sepsis. J Clin Invest. 2023, 133(14):e164585.
2. Qiuping Zhou, Lanfen Lin, Haiyan Li, Yichen Li, Nan Liu 1, Huifang Wang, Shuqi Jiang, Qian Li, Zhuo Chen, Yiyan Lin , Hui Jin, Yiyu Deng. Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat. J Neurosci Res. 2023,101(6):930-951(co-corresponding author).
3. Royster W, Jin H, Wang P, Aziz M. Extracellular CIRP decreases Siglec-G expression on B-1a cells skewing them towards a pro-inflammatory phenotype in sepsis. Mol Med. 2021, 27(1):55.
4. Gurien SD, Aziz M, Jin H, et al. Extracellular microRNA 130b-3p Inhibits eCIRP-induced Inflammation. EMBO Rep.2020,21(1): e48075.
5. Jin H, Aziz M, Ode Y, Wang P. CIRP Induces Neutrophil Reverse Transendothelial Migration in Sepsis. SHOCK. 2019. 51(5):548-556.
6. Jin H, Zhao X, Li R, et al. Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways. PLoS One. 2018, 13(1):e0192083.
7. Jin H, Chen Y, Ding C, et al. Microcirculatory Disorders and Protective Role of Xuebijing in Severe Heat Stroke. Sci Rep. 2018, 8(1):4553.
8. Hui Jin, Zhipeng Li, Xiaohua Guo, et al. Microcirculatory Disorders and Protective Role of Anti-oxidant in Severe Heat Stroke: A Rat Study. Shock. 2016, 46(6):688-695.
9. Murao A, Arif A, Brenner M, Denning NL, Jin H, Takizawa S, Nicastro B, Wang P*, Aziz M*. Extracellular CIRP and TREM-1 axis promotes ICAM-1-Rho-mediated NETosis in sepsis. FASEB J. 2020, 34(7):9771-9786.
10. Chen K, Murao A, Takiawa S, Arif A, Jin H, Jiang J, Aziz M*, Wang P*. Inhibition of efferocytosis by eCIRP-inducedneutrophil extracellular traps. J Immunol. 2021,206(4):797-906.
11. Honghe Luo, Hui Jin, et al，Cyclooxygenase-2 Up-regulates Vascular Endothelial Growth Factor via a Protein Kinase C Pathway in Non-small Cell Lung Cancer. J Exp Clin Cancer Res.2011，30（1）：6.
12. Gurien SD, Aziz M, Jin H, Wang H, He M, Al-Abed Y, Nicastro JM, Coppa GF, Wang P. Extracellular microRNA 130b-3p inhibits eCIRP-induced inflammation. EMBO Rep. 2020 Jan 7;21(1):e48075. doi: 10.15252/embr.201948075. Epub 2019 Nov 14. PMID: 31724825; PMCID: PMC10563445.
13. Ode Y, Aziz M, Jin H, Arif A, Nicastro JG, Wang P. Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis. Sci Rep. 2019 Apr 18;9(1):6252. doi: 10.1038/s41598-019-42762-1. PMID: 31000768; PMCID: PMC6472421.
14. Jin H, Tang LQ, Pan ZG, Peng N, Wen Q, Tang YQ, Su L. Ten-year retrospective analysis of multiple trauma complicated by pulmonary contusion. Mil Med Res. 2014 May 1;1:7. doi: 10.1186/2054-9369-1-7. PMID: 25722865; PMCID: PMC4336115.
15. Chen K, Murao A, Arif A, Takizawa S, Jin H, Jiang J, Aziz M, Wang P. Inhibition of Efferocytosis by Extracellular CIRP-Induced Neutrophil Extracellular Traps. J Immunol. 2021 Feb 15;206(4):797-806. doi: 10.4049/jimmunol.2000091. Epub 2020 Dec 30. PMID: 33380498; PMCID: PMC7854515.
16. Zhao X, Li R, Jin H, Jin H, Wang Y, Zhang W, Wang H, Chen W. Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways. PLoS One. 2018 Jan 26;13(1):e0192083. doi: 10.1371/journal.pone.0192083. PMID: 29373584; PMCID: PMC5786317.
17. Pan Z, Shao Y, Dong W, Liu C, Chen Y, Jin H, Tang L, Qiu J, Su L. Xuebijing attenuates hypotension through the upregulation of angiotensin II type 1 receptor-associated protein 1 in rats suffering from heat stroke. Int J Mol Med. 2014 Dec;34(6):1699-705. doi: 10.3892/ijmm.2014.1950. Epub 2014 Sep 29. PMID: 25270312.
18. Jin H, Li Z, Guo X, Tong H, Liu Z, Chen Y, Su L, Huang Q. Microcirculatory Disorders and Protective Role of Antioxidant in Severe Heat Stroke: A Rat Study. Shock. 2016 Dec;46(6):688-695. doi: 10.1097/SHK.0000000000000623. PMID: 27058049.
19. Zhou Q, Lin L, Li H, Li Y, Liu N, Wang H, Jiang S, Li Q, Chen Z, Lin Y, Jin H, Deng Y. Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat. J Neurosci Res. 2023 Jun;101(6):930-951. doi: 10.1002/jnr.25170. Epub 2023 Jan 31. PMID: 36720002.
20. Chen K, Murao A, Arif A, Takizawa S, Jin H, Jiang J, Aziz M, Wang P. Inhibition of Efferocytosis by Extracellular CIRP-Induced Neutrophil Extracellular Traps. J Immunol. 2021 Feb 15;206(4):797-806. doi: 10.4049/jimmunol.2000091. Epub 2020 Dec 30. PMID: 33380498; PMCID: PMC7854515.

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