Biography

Dr. Rwik Sen

Active Motif, Incorporated, USA

Field Application Scientist


Email: [email protected]


Qualifications

2015 Ph.D., Southern Illinois University Carbondale, USA


Publications (Selected)

  1. Fiskus, W., Piel, J., Collins, M., Hentemann, M., Cuglievan, B., Mill, C. P., ... & Bhalla, K. N. (2024). BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor. Blood, 143(20), 2059-2072.
  2. Fiskus, W., Piel, J., Collins, M., Hentemann, M., Cuglievan, B., Mill, C. P., ... & Bhalla, K. N. (2024). BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or menin inhibitor. Blood, 143(20), 2059-2072.
  3. Naik, N., Patel, M., & Sen, R. (2024). Developmental impacts of epigenetics and metabolism in COVID-19. Journal of developmental biology, 12(1), 9.
  4. Evans-Holm, M., Lumbres, N., Sen, R., Montilla-Perez, P., Paradise, M. A., & Lentz, P. (2024). Improved high-throughput genomic analysis of urine samples using pixelated-ultrasound to enable personalized genomic profiling and therapeutic developments in cancer. Cancer Research, 84(6_Supplement), 332-332.
  5. Sen, R. (2024, January). Novel High-Throughput NGS-Based Epigenetics-Exploratory and Targeted-Methods and Their Selection in Project Design. In Plant and Animal Genome Conference/PAG 31 (January 12-17, 2024). PAG.
  6. Chapin, N., & Sen, R. (2023). COVID-19 phenomics. In Omics approaches and technologies in COVID-19 (pp. 191-218). Academic Press.
  7. Sen, R., Tran, N., Traynor, S., Maina, E., & Poole, J. (2023). Novel epigenetics technology for high-throughput processing of limited samples to study cancer using cavitation-based pixelated ultrasound and tagmentation-indexing ChIP-Seq. Cancer Research, 83(7_Supplement), 4731-4731.
  8. Sen, R., Sarkar, S., Chlamydas, S., Garbati, M., & Barnes, C. (2023). Epigenetic features, methods, and implementations associated with COVID-19. In Omics approaches and technologies in COVID-19 (pp. 161-175). Academic Press.
  9. Barman, P., Sen, R., Kaja, A., Ferdoush, J., Guha, S., Govind, C. K., & Bhaumik, S. R. (2022). Genome-wide regulations of the preinitiation complex formation and elongating RNA polymerase II by an E3 ubiquitin ligase, San1. Molecular and Cellular Biology, 42(1), e00368-21.
  10. Sarkar, S., & Sen, R. (2022). Insights into Cardiovascular Defects and Cardiac Epigenome in the Context of COVID-19. Epigenomes, 6(2), 13.
  11. Verlander, Z., Cummings, A., Brown, H. M., & Sen, R. (2022). Advances in understanding epigenetic impacts on dendritic cell regulation and function. Clinical and Translational Discovery, 2(2), e53.
  12. Sen, R. (2022). Neurodevelopmental Disorders: Epigenetic Implications and Potential Analysis Methods. In Proteins Associated with Neurodevelopmental Disorders (pp. 91-116). Singapore: Springer Singapore.
  13. Sen, R., Garbati, M., Bryant, K., & Lu, Y. (2021). Epigenetic mechanisms influencing COVID-19. Genome, 64(4), 372-385.
  14. Sen, R. (2021). High-throughput approaches of diagnosis and therapies for COVID-19: Antibody panels, proteomics and metabolomics. Future Drug Discovery, 3(1), FDD55.
  15. Francoeur, N., & Sen, R. (2021). Advances in cardiac development and regeneration using zebrafish as a model system for high-throughput research. Journal of Developmental Biology, 9(4), 40.
  16. Sen, R., & Barnes, C. (2021). Do transgenerational epigenetic inheritance and immune system development share common epigenetic processes?. Journal of Developmental Biology, 9(2), 20.
  17. Dogra, N., Ledesma-Feliciano, C., & Sen, R. (2021). Developmental aspects of SARS-CoV-2, potential role of exosomes and their impact on the human transcriptome. Journal of Developmental Biology, 9(4), 54.
  18. Appiasie, D., Guerra, D. J., Tanguay, K., Jelinek, S., Guerra, D. D., & Sen, R. (2021). “Multiomics” approaches to understand and treat COVID-19: Mass spectrometry and next-generation sequencing. BioChem, 1(3), 210-237.
  19. Shull, L. C., Sen, R., Menzel, J., Goyama, S., Kurokawa, M., & Artinger, K. B. (2020). The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development. Developmental biology, 461(2), 132-144.
  20. Ferdoush, J., Sen, R., Durairaj, G., Barman, P., Kaja, A., Guha, S., & Bhaumik, S. R. (2020). An F-box protein, Mdm30, interacts with TREX subunit Sub2 to regulate cellular abundance cotranscriptionally in orchestrating mRNA export independently of splicing and mitochondrial function. Molecular and Cellular Biology, 40(7), e00570-19.
  21. Sen, R., Lencer, E., Geiger, E. A., Jones, K. L., Shaikh, T. H., & Artinger, K. B. (2020). The role of KMT2D and KDM6A in cardiac development: A cross-species analysis in humans, mice, and zebrafish. bioRxiv, 2020, 2004.
  22. Hsu, J. Y., Major, J. L., Riching, A. S., Sen, R., Pires da Silva, J., & Bagchi, R. A. (2020). Beyond the genome: challenges and potential for epigenetics-driven therapeutic approaches in pulmonary arterial hypertension. Biochemistry and Cell Biology, 98(6), 631-646.
  23. Sen, R., Lencer, E., Geiger, E. A., Jones, K., Shaikh, T. H., & Artinger, K. B. (2020). The role of Kabuki Syndrome genes KMT2D and KDM6A in development: Analysis in Human sequencing data and compared to mice and zebrafish. bioRxiv, 2020-04.
  24. Sarkar, S., & Sen, R. (2020). COVID-19 and Cardiovascular Diseases: The Vicious Cycle. Biomed J Sci & Tech Res, 30, 22965-7.


Profile Details

https://orcid.org/0000-0003-2853-2378

https://www.activemotif.com/meet-our-experts

https://scholar.google.com/citations?user=PX2nIpoAAAAJ&hl=zh-CN&oi=ao

https://www.researchgate.net/profile/Rwik-Sen

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